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1 Contributo su Rivista 63584
- 1.1 Articolo in rivista 59680
- 1.2 Recensione in rivista 978
- 1.3 Scheda bibliografica 76
- 1.4 Nota a sentenza 581
- 1.5 Abstract in rivista 2248
- 1.6 Traduzione in rivista 21

2 Contributo in Volume 18999
- 2.1 Contributo in volume (Capitolo o Saggio) 16721
- 2.2 Prefazione/Postfazione 460
- 2.3 Breve introduzione 150
- 2.4 Voce (in dizionario o enciclopedia) 801
- 2.5 Traduzione in volume 121
- 2.6 Recensione in volume 64
- 2.7 Schede di catalogo 682

3 Libro 2793
- 3.1 Monografia o trattato scientifico 2607
- 3.2 Concordanza 4
- 3.3 Indice 3
- 3.4 Bibliografia 8
- 3.5 Edizione critica 40
- 3.6 Pubblicazione di fonti inedite 23
- 3.7 Commento scientifico 40
- 3.8 Traduzione di libro 68

4 Contributo in Atti di Convegno (Proceeding) 19846
- 4.1 Contributo in Atti di convegno 15199
- 4.2 Abstract in Atti di convegno 3702
- 4.3 Poster 945

5 Altro 1881
- 5.01 Composizione 15
- 5.02 Disegno 55
- 5.03 Design 144
- 5.04 Performance 33
- 5.05 Esposizione 164
- 5.06 Mostra 305
- 5.07 Manufatto 2
- 5.08 Prototipo d'arte e relativi progetti 35
- 5.09 Cartografia 32
- 5.10 Banca dati 26
- 5.11 Software 16
- 5.12 Altro 971
- 5.13 Progetto architettonico 83

6 Brevetti 294
- 6.1 Brevetto 294

7 Curatele 1450
- 7.1 Curatela 1450

8 Tesi di dottorato 2
- 8.1 Tesi di dottorato 2

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Hepatocellular carcinoma (HCC) tumor microenvironment is more suppressive than colorectal cancer liver metastasis (CRLM) tumor microenvironment

Background and purposeWhile HCC is an inflammation-associated cancer, CRLM develops on permissive healthy liver microenvironment. To evaluate the immune aspects of these two different environments, peripheral blood-(PB), peritumoral-(PT) and tumoral tissues-(TT) from HCC and CRLM patients were evaluated.Methods40 HCC and 34 CRLM were enrolled and freshly TT, PT and PB were collected at the surgery. PB-, PT- and TT-derived CD4(+)CD25(+) Tregs, M/PMN-MDSC and PB-derived CD4(+)CD25(-) T-effector...

Targeting CXCR4 impaired T regulatory function through PTEN in renal cancer patients

Background Tregs trafficking is controlled by CXCR4. In Renal Cell Carcinoma (RCC), the effect of the new CXCR4 antagonist, R54, was explored in peripheral blood (PB)-Tregs isolated from primary RCC patients.Methods PB-Tregs were isolated from 77 RCC patients and 38 healthy donors (HDs). CFSE-T effector-Tregs suppression assay, IL-35, IFN-gamma, IL-10, TGF-beta 1 secretion, and Nrp-1+Tregs frequency were evaluated. Tregs were characterised for CTLA-4, PD-1, CD40L, PTEN, CD25, TGF-beta 1, FOXP...

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