IRIS
PALAZZO, Enza
 Distribuzione geografica
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Continente #
NA - Nord America 2.871
EU - Europa 2.534
AS - Asia 734
SA - Sud America 7
OC - Oceania 2
Continente sconosciuto - Info sul continente non disponibili 1
Totale 6.149
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Nazione #
US - Stati Uniti d'America 2.869
IE - Irlanda 859
CN - Cina 572
UA - Ucraina 375
IT - Italia 334
GB - Regno Unito 311
DE - Germania 293
TR - Turchia 138
SE - Svezia 135
FI - Finlandia 100
GR - Grecia 68
BE - Belgio 21
FR - Francia 17
BR - Brasile 5
LB - Libano 5
PL - Polonia 5
IR - Iran 4
JP - Giappone 4
NL - Olanda 4
ES - Italia 3
IN - India 3
CL - Cile 2
NZ - Nuova Zelanda 2
RS - Serbia 2
VN - Vietnam 2
AE - Emirati Arabi Uniti 1
CA - Canada 1
CH - Svizzera 1
CZ - Repubblica Ceca 1
DK - Danimarca 1
EU - Europa 1
HK - Hong Kong 1
HU - Ungheria 1
IL - Israele 1
KH - Cambogia 1
KR - Corea 1
MC - Monaco 1
MX - Messico 1
RO - Romania 1
RU - Federazione Russa 1
SG - Singapore 1
Totale 6.149
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Città #
Dublin 857
Chandler 595
Jacksonville 567
Beijing 146
Ashburn 129
Bremen 114
Princeton 111
Boardman 107
Dearborn 102
Medford 96
Ann Arbor 88
Wilmington 73
San Mateo 70
Woodbridge 69
Hefei 63
Caserta 61
Roxbury 61
Nanjing 58
New York 55
Kunming 51
Jinan 33
Cambridge 31
Naples 31
Düsseldorf 24
Guangzhou 22
Brussels 21
Hebei 18
Houston 18
Cava 17
Des Moines 16
Nanchang 16
Zhengzhou 16
Mugnano di Napoli 15
Norwalk 15
Shenyang 14
Venice 14
Auburn Hills 13
Mountain View 13
Napoli 11
Redwood City 9
Baotou 8
Hangzhou 8
Lanzhou 8
Los Angeles 8
Ningbo 8
Helsinki 7
Taizhou 7
Xian 7
Changsha 6
Chongqing 6
Milan 6
Paris 6
Shanghai 6
Fairfield 5
Grafing 5
Haikou 5
Hanover 5
Pioltello 5
Rome 5
Santa Maria Capua Vetere 5
Tianjin 5
Aversa 4
Chengdu 4
Fuzhou 4
Monza 4
Shaoxing 4
Taiyuan 4
Cedar Knolls 3
Falls Church 3
Guiyang 3
L'aquila 3
Lappeenranta 3
Quzhou 3
Redmond 3
Teano 3
Altamura 2
Busto Arsizio 2
Casoria 2
Castellaneta 2
Cork 2
Dong Ket 2
Florence 2
Fremont 2
Jinhua 2
Krakow 2
Latina 2
Nanning 2
Omaha 2
Palermo 2
Rockville 2
Siena 2
Solferino 2
Tappahannock 2
Taranto 2
Verona 2
Villar Focchiardo 2
Wroclaw 2
Wuhan 2
Yakima 2
Aiello del Sabato 1
Totale 4.068
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Nome #
SOSTITUZIONE BIOISOSTERICA DEL GRUPPO AMMIDICO DI 4-CHINOLON-3-CARBOSSAMIDI6-SOSTITUITE:LIGANDI CB2 POTENTI E SELETTIVI PROVVISTI DI MIGLIOR PROFILO CHIMICO-FISICO . 126
"2-FENIL-IMIDAZO[1,2-B]PIRIDAZINE AD ATTIVITA' ANALGESICA ED ANTIEPILETTICA" 120
MMPIP, an mGluR7-selective negative allosteric modulator, alleviates pain and normalizes affective and cognitive behavior in neuropathic mice 97
USO DEI BISFOSFONATI PER LA PREPARAZIONE DI FORMULAZIONI FARMACEUTICHE PER IL TRATTAMENTO DEI SINTOMI ASSOCIATI A DOLORE NEUROPATICO 97
D-Aspartate drinking solution alleviates pain and cognitive impairment in neuropathic mice. 97
1-(2′,4′-dichlorophenyl)-6-methyl-N-cyclohexylamine-1,4-dihy droindeno[1,2-c]pyrazole-3-carboxamide, a novel CB2 agonist, alleviates neuropathic pain through functional microglial changes in mice 90
1-(2',4'-dichlorophenyl)-6-methyl-N-cyclohexylamine-1,4-dihydroindeno[1,2-c]pyrazole-3-carboxamide, a novel CB2 agonist, alleviates neuropathic pain through functional microglial changes in mice. Neurobiol Dis. 2010 Jan;37(1):177-85. Epub 2009 Oct 3. PubMed PMID: 19804829 85
Profarmaco galattosilato della n-omega-nitro-l-arginina (nagal) ad uso analgesico ed antinfiammatorio con migliori caratteristiche farmacocinetiche e di tollerabilità del farmaco di partenza 84
Dorsal striatum metabotropic glutamate receptor 8 affects nocifensive responses and rostral ventromedial medulla cell activity in neuropathic pain conditions. 79
The antinociceptive effect of 2-chloro-2'-C-methyl-N6-cyclopentyladenosine (2'-Me-CCPA), a highly selective adenosine A1 receptor agonist, in the rat 79
La patologia dolorosa cronica e il problema della ‘oppiofobia’ 78
Changes in cannabinoid receptor subtype 1 activity and interaction with metabotropic glutamate subtype 5 receptors in the periaqueductal gray-rostral ventromedial medulla pathway in a rodent neuropathic pain model. 73
Palmitoylethanolamide reduces neuropsychiatric behaviors by restoring cortical electrophysiological activity in a mouse model of mild traumatic brain injury 73
The blockade of the transient receptor potential vanilloid type 1 and fatty acid amide hydrolase decreases symptoms and central sequelae in the medial prefrontal cortex of neuropathic rats. 72
Interaction between vanilloid and glutamate receptors in the central modulation of nociception 72
Datura stramonium intake: a report on three cases. 72
EP1 receptor within the ventrolateral periaqueductal grey controls thermonociception and rostral ventromedial medulla cell activity in healthy and neuropathic rat 72
Exposure to allergen causes changes in nts neural activities after intratracheal capsaicin application, in endocannabinoid levels and in the glia morphology of nts 71
Selective melatonin MT2 receptor ligands relieve neuropathic pain through modulation of brainstem descending antinociceptive pathways 69
Effects of intra-ventrolateral periaqueductal grey palmitoylethanolamide on thermoceptive threshold and rostral ventromedial medulla cell activity 69
Differential roles of mGlu8 receptors in the regulation of glutamate and gamma-aminobutyric acid release at periaqueductal grey level. Neuropharmacology 69
Changes in spinal and supraspinal endocannabinoid levels in neuropathic rats 69
Metabotropic glutamate receptor subtype 7 in the dorsal striatum oppositely modulates pain in sham and neuropathic rats 69
Intraperiaqueductal gray glycine and D-serine exert dual effects on rostral ventromedial medulla ON- and OFF-cell activity and thermoceptive threshold in the rat 68
Uso di bifosfonati per la preparazione di formulazioni farmaceutiche per il trattamento dei sintomi associati a dolore neuropatico. 68
D-aspartate modulates nociceptive-specific neuron activity and pain threshold in inflammatory and neuropathic pain condition in mice 67
Characterisation of mGluRs which modulate nociception in the PAG of the mouse 67
Elevation of endocannabinoid levels in the ventrolateral periaqueductal grey through inhibition of fatty acid amide hydrolase affects descending nociceptive pathways via both CB1 and TRPV1 receptors. J Pharmacol Exp The 66
Effects of (S)-3,4-DCPG, an mGlu8 receptor agonist, on inflammatory and neuropathic pain in mice 66
Characterization of mGluRs which modulate nociception in the PAG of the mouse 66
Salvinorin A reduces mechanical allodynia and spinal neuronal hyperexcitability induced by peripheral formalin injection. 65
Metabotropic glutamate receptor 7: From synaptic function to therapeutic implications 65
Intra-periaqueductal grey microinjections of an imidazo[1,2-b]pyridazine derivative, DM2, affects rostral ventromedial medulla cell activity and shows antinociceptive effect 64
Differential roles of mGlu8 receptors in the regulation of glutamate and gamma-aminobutyric acid release at periaqueductal grey level 64
The analgesic effect of N-arachidonoyl-serotonin, a FAAH inhibitor and TRPV1 receptor antagonist, associated with changes in rostral ventromedial medulla and locus coeruleus cell activity in rats 63
Role of reactive oxygen species and spinal cord apoptotic genes in the development of neuropathic pain 63
Effects of persistent nociception on periaqueductal gray glycine release 63
Role of metabotropic glutamate receptor 1 in the basolateral amygdala-driven prefrontal cortical deactivation in inflammatory pain in the rat 61
Intra-Periaqueductal Gray glycine and D-serine exert dual effects on the Rostral Ventromedial Medulla ON and OFF cell activity and thermal threshold in the rat 61
In vitro and in vivo pharmacology of synthetic olivetol- or resorcinol-derived cannabinoid receptor ligands 61
Supraspinal metabotropic glutamate receptor subtype 8: a switch to turn off pain. 60
Group I metabotropic glutamate receptors modulate glutamate and gamma-aminobutyric acid release in the periaqueductal grey of rats. 59
Effects of a metabotropic glutamate receptor subtype 7 negative allosteric modulator in the periaqueductal grey on pain responses and rostral ventromedial medulla cell activity in rat 58
Effects of imipramine on raphe nuclei and prefrontal cortex extracellular serotonin levels in the rat 58
Effects of diethylenetriamine on NMDA-induced increase of blood pressure in rats 57
Transient receptor potential vanilloid type 1 and pain development. 57
N-methyl-D-aspartate Receptors in the Prelimbic Cortex are Critical for the Maintenance of Neuropathic Pain. 57
Moving towards supraspinal TRPV1 receptors for chronic pain relief 56
Differential effects of mGluR7 and mGluR8 activation on pain-related synaptic activity in the amygdala. 56
Metabotropic glutamate receptor 5 and dorsal raphe serotonin release in inflammatory pain in rat 55
Interaction between metabotropic and NMDA glutamate receptors participate in the periaqueductal grey pain modulatory system 55
The galactosylation of N()-nitro-L-arginine enhances its anti-nocifensive or anti-allodynic effects by targeting glia in healthy and neuropathic mice 55
Nociception modulation by supraspinal group III metabotropic glutamate receptors 55
Periaqueductal gray metabotropic glutamate receptor subtype 7 and 8 mediate opposite effects on amino acid release, rostral ventromedial medulla cell activities, and thermal nociception 54
Metabotropic and NMDA glutamate receptors participate in the cannabinoid-induced antinociception 54
Metabotropic glutamate receptors modulate serotonin release in the rat periaqueductal gray matter 54
Type I and II metabotropic glutamate receptors modulate periaqueductal grey glycine release: interaction between mGlu2/3 and A1 adenosine receptors 53
Periaqueductal gray metabotropic glutamate receptors in pain modulation 53
“Role of glutamate in periaqueductal grey induced analgesia.” 53
Metabotropic glutamate receptor subtype 8 in the amygdala modulates thermal threshold, neurotransmitter release, and rostral ventromedial medulla cell activity in inflammatory pain. 52
Role of endocannabinoids in neuron-glial crosstalk 52
Effects of URB597, an inhibitor of fatty acid amide hydrolase (FAAH), on analgesic activity of paracetamol. 52
Targeting Supraspinal TRP Channels for Pain Relief 52
Enhanced serotonin and mesolimbic dopamine transmissions in a rat model of neuropathic pain. 52
Behavioral, Biochemical and Electrophysiological Changes in Spared Nerve Injury Model of Neuropathic Pain 52
Effects of docosahexaenoic acid on [Ca2+]i increase induced by doxorubicin in ventricular rat cardiomyocytes 51
Development of a potent inhibitor of 2-arachidonoylglycerol hydrolysis with antinociceptive activity in vivo 51
Palmitoylethanolamide reduces granuloma-induced hyperalgesia by modulation of mast cell activation in rats. 51
Periaqueductal gray matter metabotropic glutamate receptors modulate formalin-induced nociception 50
In vitro and in vivo pharmacological characterization of two novel selective cannabinoid CB(2) receptor inverse agonists 50
Periaqueductal grey CB1 cannabinoid and metabotropic glutamate subtype 5 receptors modulate changes in rostral ventromedial medulla neuronal activities induced by subcutaneous formalin in the rat 50
The prokineticin receptor agonist Bv8 increases GABA release in the periaqueductal grey and modifies RVM cell activities and thermoceptive reflexes in the rat 49
The role of cannabinoid receptors in the descending modulation of pain 49
Tonic endovanilloid facilitation of glutamate release in brainstem descending antinociceptive pathways 49
Metabotropic glutamate receptors modulate periaqueductal grey descending analgesic system 49
Group I metabotropic glutamate receptors modulate glutamate and γ-aminobutyric acid release in the periaqueductal grey of rats 49
Elevation of endocannabinoid levels in the ventrolateral periaqueductal grey through inhibition of fatty acid amide hydrolase affects descending nociceptive pathways via both cannabinoid receptor type 48
Metabotropic glutamate receptors modulate serotonin release in the rat periaqueductal grey matter 48
L-Cysteinesulfinic acid modulates cardiovascular function in the periaqueductal gray area of rat 48
Non-psychoactive cannabinoids modulate the descending pathway of antinociception in anaesthetized rats through several mechanisms of action. 48
Effects of URB597, an inhibitor of fatty acid amide hydrolase (FAAH), on analgesic activity of paracetamol. Neuro Endocrinol Lett. 2010;31(4):507-11. PubMed PMID: 20802454 48
The Modulation of Pain by Metabotropic Glutamate Receptors 7 and 8 in the Dorsal Striatum. 48
Neuropathic pain and the endocannabinoid system in the dorsal raphe: pharmacological treatment and interactions with the serotonergic system 47
Group III mGluR7 and mGluR8 in the amygdala differentially modulate nocifensive and affective pain behaviors 47
TRPV1 in Neuropathic Pain and Neuropsychiatric Disorders 46
New Insights on Neuropathic Pain Mechanisms as a Source for Novel Therapeutical Strategies 46
TRPV1-Dependent and -Independent Alterations in the Limbic Cortex of Neuropathic Mice: Impact on Glial Caspases and Pain Perception 45
Supraspinal metabotropic glutamate receptors: a target for pain relief and beyond. 45
Characterization of the sensory, affective, cognitive, biochemical, and neuronal alterations in a modified chronic constriction injury model of neuropathic pain in mice 45
Role of periaqueductal grey prostaglandin receptors in formalin-induced hyperalgesia 44
Role of TRPV1 receptors in descending modulation of pain 42
Neurochemical and behavioral alterations in glucocorticoid receptor-impaired transgenic mice after chronic mild stress 42
Group II Metabotropic Glutamate Receptors: Role in Pain Mechanisms and Pain Modulation. 42
Metabotropic Glutamate Receptor 5 and 8 Modulate the Ameliorative Effect of Ultramicronized Palmitoylethanolamide on Cognitive Decline Associated with Neuropathic Pain 42
Pharmacological Considerations for the Use of General Anesthetics in the Elderly 42
Endogenous modulator of TRP channels 40
Editorial: Metabotropic Glutamate Receptors and Neurological/Psychiatric Disorders 40
The cold case of metabotropic glutamate receptor 6: Unjust detention in the retina? 40
PEA-OXA ameliorates allodynia, neuropsychiatric and adipose tissue remodeling induced by social isolation. 40
null 39
Totale 5.961
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Categoria #
all - tutte 20.290
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 20.290
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/201930 0 0 0 0 0 0 0 0 0 7 16 7
2019/20201.197 108 100 4 69 104 113 389 164 71 30 39 6
2020/2021896 87 9 110 55 159 13 126 88 10 117 93 29
2021/2022769 75 5 2 12 249 14 13 14 37 78 54 216
2022/20232.025 124 20 33 220 277 198 14 154 891 18 37 39
2023/2024599 68 26 29 56 202 75 14 121 4 4 0 0
Totale 6.382