Urine concentrating defect is a common dysfunction in ciliopathies, even though its underlying mechanism and its prognostic meaning are largely unknown. This study assesses renal function in a cohort of 54 Bardet-Biedl syndrome (BBS) individuals and analyses whether renal hyposthenuria is the result of specific tubule dysfunction and predicts renal disease progression.
Urine concentrating defect as presenting sign of progressive renal failure in Bardet-Biedl syndrome patients
Zacchia, Miriam;Torella, Annalaura;Onore, Maria Elena;Trepiccione, Francesco;Vitagliano, Caterina;Alessandra, Perna;Simonelli, Francesca;Nigro, Vincenzo;Capasso, Giovambattista;Viggiano, Davide
2021
Abstract
Urine concentrating defect is a common dysfunction in ciliopathies, even though its underlying mechanism and its prognostic meaning are largely unknown. This study assesses renal function in a cohort of 54 Bardet-Biedl syndrome (BBS) individuals and analyses whether renal hyposthenuria is the result of specific tubule dysfunction and predicts renal disease progression.File in questo prodotto:
Non ci sono file associati a questo prodotto.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
