IRIS
FILOSA, Rosanna
 Distribuzione geografica
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Continente #
EU - Europa 4.127
NA - Nord America 1.941
AS - Asia 1.456
SA - Sud America 295
Continente sconosciuto - Info sul continente non disponibili 206
AF - Africa 28
OC - Oceania 3
Totale 8.056
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Nazione #
RU - Federazione Russa 2.632
US - Stati Uniti d'America 1.908
SG - Singapore 537
IE - Irlanda 430
CN - Cina 332
IT - Italia 314
BR - Brasile 236
UA - Ucraina 218
HK - Hong Kong 207
GB - Regno Unito 172
VN - Vietnam 160
DE - Germania 120
KR - Corea 73
GR - Grecia 60
FI - Finlandia 59
FR - Francia 54
TR - Turchia 42
IN - India 24
AR - Argentina 23
CA - Canada 23
JP - Giappone 21
BE - Belgio 13
SE - Svezia 13
BD - Bangladesh 11
EC - Ecuador 10
PL - Polonia 9
ZA - Sudafrica 9
CO - Colombia 8
NL - Olanda 8
CL - Cile 7
ID - Indonesia 7
MX - Messico 6
AT - Austria 5
CZ - Repubblica Ceca 5
IQ - Iraq 5
PK - Pakistan 5
KE - Kenya 4
MA - Marocco 4
IR - Iran 3
KZ - Kazakistan 3
MY - Malesia 3
NP - Nepal 3
PE - Perù 3
PH - Filippine 3
SN - Senegal 3
TN - Tunisia 3
UZ - Uzbekistan 3
VE - Venezuela 3
AE - Emirati Arabi Uniti 2
AU - Australia 2
BG - Bulgaria 2
BO - Bolivia 2
BY - Bielorussia 2
CH - Svizzera 2
DZ - Algeria 2
EG - Egitto 2
ES - Italia 2
JO - Giordania 2
KW - Kuwait 2
PY - Paraguay 2
RO - Romania 2
AL - Albania 1
AM - Armenia 1
BN - Brunei Darussalam 1
GE - Georgia 1
GT - Guatemala 1
HN - Honduras 1
HR - Croazia 1
JM - Giamaica 1
LV - Lettonia 1
MD - Moldavia 1
MM - Myanmar 1
PW - Palau 1
QA - Qatar 1
RS - Serbia 1
SA - Arabia Saudita 1
SC - Seychelles 1
TJ - Tagikistan 1
TT - Trinidad e Tobago 1
TW - Taiwan 1
UY - Uruguay 1
Totale 7.850
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Città #
Moscow 900
Dublin 430
Jacksonville 325
Santa Clara 235
Singapore 227
San Jose 226
Hong Kong 203
Chandler 162
Ashburn 91
Beijing 79
Council Bluffs 72
Seoul 71
Ho Chi Minh City 62
Princeton 61
Medford 60
Ann Arbor 58
Roxbury 58
Caserta 47
Hanoi 40
Bremen 32
Woodbridge 31
Wilmington 25
Munich 24
Dallas 22
Mountain View 22
Naples 22
Hefei 21
Los Angeles 21
New York 19
Jinan 16
Napoli 16
Bengaluru 15
Des Moines 15
Düsseldorf 15
São Paulo 14
Brussels 13
Nuremberg 13
The Dalles 13
Nanjing 11
Campodarsego 10
Tokyo 10
Boardman 9
Dearborn 9
Rome 9
Chicago 8
Norwalk 8
Da Nang 7
Phoenix 7
Rio de Janeiro 7
San Mateo 7
Turku 7
Arzano 6
Auburn Hills 6
Changsha 6
Fortaleza 6
Guayaquil 6
Monte Compatri 6
Tianjin 6
Warsaw 6
Amsterdam 5
Brasília 5
Jakarta 5
Johannesburg 5
Latina 5
Montreal 5
Novokuznetsk 5
Ottawa 5
Redwood City 5
Salerno 5
Segrate 5
Shanghai 5
Zhengzhou 5
Belo Horizonte 4
Brno 4
Can Tho 4
Frankfurt am Main 4
Guangzhou 4
Kunming 4
London 4
Nairobi 4
Thái Nguyên 4
Venice 4
Afragola 3
Boston 3
Brooklyn 3
Buenos Aires 3
Cambridge 3
Curitiba 3
Dakar 3
Guarulhos 3
Haiphong 3
Hangzhou 3
Hebei 3
Houston 3
Lima 3
Louisville 3
Marcianise 3
Matera 3
Milan 3
Newark 3
Totale 4.092
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Nome #
Derivati 3-eteroarilfenolici come nuovi potenti inibitori della 5-lipossigenasi 276
A hydroquinone-based derivative elicits apoptosis and autophagy via activating a ros-dependent unfolded protein response in human glioblastoma 189
The 1,4 benzoquinone-featured 5-lipoxygenase inhibitor RF-Id induces apoptotic death through downregulation of IAPs in human glioblastoma cells 182
Anti-inflammatory drugs as anticancer agents 182
1-methoxy-canthin-6-one and related β-carbolines: From natural compound to synthesis and biological activities 166
Role of adiponectin in sphingosine-1-phosphate induced airway hyperresponsiveness and inflammation 154
Cyclohexa-2,5-diene-1,4-dione-based antiproliferative agents: design, synthesis, and cytotoxic evaluation 152
Structural insight into the optimization of ethyl 5-hydroxybenzo[g] indol-3-carboxylates and their bioisosteric analogues as 5-LO/mPGES-1 dual inhibitors able to suppress inflammation 151
In vitro antiviral and immunomodulatory activity of arbidol and structurally related derivatives in herpes simplex virus type 1-infected human keratinocytes (HaCat). 149
Formulation and characterization of solid lipid nanoparticles loading rf22-c, a potent and selective 5-lo inhibitor, in a monocrotaline-induced model of pulmonary hypertension 149
Hyaluronan hydrogels with a low degree of modification as scaffolds for cartilage engineering 148
Design of inhibitors of influenza virus membrane fusion: Synthesis, structure-activity relationship and in vitro antiviral activity of a novel indole series. 144
Structure-activity relationship study of arbidol derivatives as inhibitors of chikungunya virus replication 143
Is molecular size a discriminating factor in hyaluronan interaction with human cells? 142
Circulating Regulatory T-Cells in Monoclonal Gammopathies of Uncertain Significance and Multiple Myeloma: In Search of a Role 140
Design and synthesis of functionalized 4-aryl-Catechol derivatives as new antinflammatory agents with in vivo efficacy 136
Bifunctional phase-transfer catalysis in the asymmetric synthesis of biologically active isoindolinones 136
Active methylene compounds in a very effective approach to 3-substituted isobenzofuranones through tandem aldol/lactonization reactions 135
Cascade reactions of glycine Schiff bases and chiral phase transfer catalysts in the synthesis of alpha-amino acids 3-substituted phthalides or isoindolinones 135
Optimization of hyaluronan-based eye drop formulations 134
Novel series of benzoquinones with high potency against 5-lipoxygenase in human polymorphonuclear leukocytes 133
A novel pyrimidine tetrad contributing to stabilize tetramolecular G-quadruplex structures 133
Circulating Regulatory T-Cells in Monoclonal Gammopathies of Uncertain Significance and Multiple Myeloma: In Search of a Role 133
Formulation of Solid Lipid Nanoparticles Loaded with Nociceptin/Orphanin FQ (N/OFQ) and Characterization in a Murine Model of Airway Hyperresponsiveness 132
Further studies on ethyl 5-hydroxy-indole-3-carboxylate scaffold: Design, synthesis and evaluation of 2-phenylthiomethyl-indole derivatives as efficient inhibitors of human 5-lipoxygenase 131
Antioxidant activity of diphenylpropionamide derivatives: Synthesis, biological evaluation and computational analysis 129
Binding of harmine derivatives to DNA: A Spectroscopic investigation 129
Recent advances in the search for novel 5-lipoxygenase inhibitors for the treatment of asthma 127
A New Approach to Di- and Tetrasubstituted 2,3-Dihydropyridin-4(1H)-ones through Aza-Diels-Alder Reaction Promoted by Silicon Tetrachloride 126
A systematic study on the use of different organocatalytic activation modes for asymmetric conjugated addition reactions of isoindolinones 126
Protective effect of piceatannol and bioactive stilbene derivatives against hypoxia-induced toxicity in H9c2 cardiomyocytes and structural elucidation as 5-LOX inhibitors 125
Design, synthesis and biological evaluation of novel bicyclo[1.1.1] pentane-based omega-acidic amino acids as glutamate receptors ligands 123
2,3-Dihydro-1,2-Diphenyl-substituted 4H-Pyridinone Derivatives as New Anti Flaviviridae Inhibitors 121
Lower pain, less itching, and faster healing after ultrasound scalpel-assisted hemorrhoidectomy using an intimate cleaner containing chlorhexidine, acid hyaluronic acid, and natural anti-inflammatories: a multicenter observational case-control study 119
Exploring the role of chloro and methyl substitutions in 2- phenylthiomethyl-benzoindole derivatives for 5-LOX enzyme inhibition 119
3-Carboxylate Substituted Isoindolinones in K2CO3-Catalyzed Michael Reactions 117
Evaluation of alternative strategies to optimize ketorolac transdermal delivery 117
Synthesis and cytotoxic activity of new β-carboline derivatives 112
Phenolics from Castanea sativa leaves and their effects on UVB-induced damage 111
Nociceptin/Orphanin Fq in inflammation and remodeling of the small airways in experimental model of airway hyperresponsiveness 107
The aldol addition of readily enolizable 1,3-dicarbonyl compounds to 2-cyanobenzaldehyde in the synthesis of novel 3-substituted isoindolinones 99
Optimization of benzoquinone and hydroquinone derivatives as potent inhibitors of human 5-lipoxygenase 98
Potent inhibition of human 5-lipoxygenase and microsomal prostaglandin E-2 synthase-1 by the anti-carcinogenic and anti-inflammatory agent embelin 97
Synthesis and preliminary biological evaluation of 2 '-substituted 2-(3 '-carboxybicyclo[1.1.1]-pentyl)glycine derivatives as group I selective metabotropic glutamate receptor ligands 97
Elucidation of the molecular mechanism and the efficacy in vivo of a novel 1,4-benzoquinone that inhibits 5-lipoxygenase. 96
Synthesis of beta-hydroxymalonates: the direct aldol addition of malonates to aldehydes in the presence of SiCl4 and i-Pr2EtN 95
Design, synthesis, biophysical and biological studies of trisubstituted naphthalimides as G-quadruplex ligands 94
Structure-based design, synthesis and preliminary anti-inflammatory activity of bolinaquinone analogues 91
Improved thrombin binding aptamer analogues containing inversion of polarity sites: Structural effects of extra-residues at the ends 91
Synthesis and Reactivity of the 3-Substituted Isoindolinone Framework to Assemble Highly Functionalized Related Structures 90
Discovery and biological evaluation of novel 1,4-benzoquinone and related resorcinol derivatives that inhibit 5-lipoxygenase 89
Synthesis and antiproliferative properties of N-3/8-disubstituted 3,8-diazabicyclo[3.2.1]octane analogues of 3,8-bis[2-(3,4,5-trimethoxyphenyl)pyridin-4-yl]methyl-piperazine 89
Discovery of Novel multi-target Indole-based Derivatives as Potent and Selective Inhibitors of Chikungunya Virus Replication 88
Diastereoselectivity in the alkylation of 4-fluoroproline methyl esters 87
Synthesis and biological evaluation of (2S)-and (2R)-2-(3 '-phosphonobicyclo[1.1.1]pentyl)glycines as novel group III selective metabotropic glutamate receptor ligands 86
Natural compounds in anti-leukaemic therapy: a review 86
Synthesis and pharmacological evaluation of functionalized isoindolinones on GABA-activated chloride currents in rat cerebellum granule cells in culture 85
Diabetes mellitus and male aging: Pharmacotherapeutics and clinical implications 84
Trimethylchlorosilane and Silicon Tetrachloride in Two Novel Methodologies for the Efficient and Mild Aldol Addition of beta-Keto Esters and Malonates to Aldehydes 83
Molecular mechanism involved in the transport of a prodrug dopamine glycosyl conjugate 82
Synthesis, physicochemical properties and in vitro permeation studies of new ketorolac ester derivatives. 82
The 5-lipoxygenase inhibitor RF-22c potently suppresses leukotriene biosynthesis in cellulo and blocks bronchoconstriction and inflammation in vivo 81
New chelating agents for Cu(II), Fe(III), Al(III), and Zn(II) based on beta-diketonate-3-substituted phthalide (isobenzofuranone) and isoindolinone 81
Molecular modelling studies, synthesis and biological activity of a series of novel bisnaphthalimides and their development as new DNA topoisomerase II inhibitors 81
Organocatalytic asymmetric hydroxymethylation of isoindolinones with paraformaldehyde 80
The Introduction of Inversion of Polarity Sites in DNA G-Quadruplex Structures: Effects and Perspectives 78
Evaluation of molecular mechanisms of (Z)-3-(pentadec-10′-enyl)-catechol (litreol) and synthetic derivatives as inhibitors of human leukotriene biosynthesis 78
Multi-component, regio-selective aldol addition of beta-ketoesters to aldehydes: scope and applications 75
Totale 8.056
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Categoria #
all - tutte 28.519
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 28.519
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022401 0 0 3 10 134 6 4 14 14 66 25 125
2022/2023721 80 22 22 34 76 50 1 28 370 6 18 14
2023/2024263 19 8 10 5 109 11 3 4 12 3 13 66
2024/2025826 2 15 1 11 159 105 199 42 86 79 62 65
2025/20264.051 116 119 190 289 349 2.467 169 103 90 109 37 13
2026/2027277 26 90 161 0 0 0 0 0 0 0 0 0
Totale 8.056