IRIS
FILOSA, Rosanna
 Distribuzione geografica
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Continente #
EU - Europa 1.368
NA - Nord America 1.232
AS - Asia 281
SA - Sud America 4
AF - Africa 1
OC - Oceania 1
Totale 2.887
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Nazione #
US - Stati Uniti d'America 1.224
IE - Irlanda 428
IT - Italia 275
UA - Ucraina 215
GB - Regno Unito 163
CN - Cina 126
SG - Singapore 87
DE - Germania 81
GR - Grecia 59
FI - Finlandia 52
FR - Francia 49
TR - Turchia 39
KR - Corea 14
BE - Belgio 13
SE - Svezia 11
CA - Canada 8
CZ - Repubblica Ceca 5
RU - Federazione Russa 5
NL - Olanda 4
PL - Polonia 3
BR - Brasile 2
CL - Cile 2
ES - Italia 2
HK - Hong Kong 2
ID - Indonesia 2
IR - Iran 2
MY - Malesia 2
PK - Pakistan 2
VN - Vietnam 2
AU - Australia 1
BD - Bangladesh 1
CH - Svizzera 1
EG - Egitto 1
IN - India 1
JP - Giappone 1
MD - Moldavia 1
RS - Serbia 1
Totale 2.887
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Città #
Dublin 428
Jacksonville 324
Chandler 162
Santa Clara 132
Princeton 61
Medford 60
Ann Arbor 58
Roxbury 58
Singapore 52
Caserta 47
Beijing 41
Bremen 32
Woodbridge 31
Wilmington 24
Mountain View 22
Napoli 16
Des Moines 15
Düsseldorf 15
Jinan 14
Naples 14
Brussels 13
Seoul 13
Nanjing 11
Campodarsego 10
New York 10
Boardman 9
Dearborn 9
Norwalk 8
San Mateo 7
Arzano 6
Auburn Hills 6
Monte Compatri 6
Changsha 5
Latina 5
Novokuznetsk 5
Ottawa 5
Redwood City 5
Salerno 5
Segrate 5
Zhengzhou 5
Ashburn 4
Brno 4
Hefei 4
Kunming 4
Rome 4
Cambridge 3
Hebei 3
Houston 3
Marcianise 3
Matera 3
Munich 3
Shenyang 3
Venice 3
Amsterdam 2
Aversa 2
Benevento 2
Calcinato 2
Dong Ket 2
Elora 2
Frattaminore 2
Grafing 2
Guangzhou 2
Hangzhou 2
Hong Kong 2
Jakarta 2
Los Angeles 2
Nanchang 2
Nuremberg 2
Nürnberg 2
Paterno 2
San Felice A Cancello 2
San Mango 2
Santiago 2
Scottsdale 2
Siderno 2
Washington 2
Wuhan 2
Amalfi 1
Bari 1
Belgrade 1
Bethesda 1
Bonea 1
Borås 1
Boscoreale 1
Campobello Di Mazara 1
Castelló de la Plana 1
Chabrey 1
Chester 1
Châtenay-malabry 1
Colle di Val d'Elsa 1
Dhaka 1
Florence 1
Forlì 1
Francolise 1
Fremont 1
Gallese 1
Gazi 1
Gîza 1
Haikou 1
Handan 1
Totale 1.869
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Nome #
Derivati 3-eteroarilfenolici come nuovi potenti inibitori della 5-lipossigenasi 173
The 1,4 benzoquinone-featured 5-lipoxygenase inhibitor RF-Id induces apoptotic death through downregulation of IAPs in human glioblastoma cells 89
Role of adiponectin in sphingosine-1-phosphate induced airway hyperresponsiveness and inflammation 86
1-methoxy-canthin-6-one and related β-carbolines: From natural compound to synthesis and biological activities 77
Hyaluronan hydrogels with a low degree of modification as scaffolds for cartilage engineering 77
Structural insight into the optimization of ethyl 5-hydroxybenzo[g] indol-3-carboxylates and their bioisosteric analogues as 5-LO/mPGES-1 dual inhibitors able to suppress inflammation 72
Structure-activity relationship study of arbidol derivatives as inhibitors of chikungunya virus replication 68
Novel series of benzoquinones with high potency against 5-lipoxygenase in human polymorphonuclear leukocytes 66
Protective effect of piceatannol and bioactive stilbene derivatives against hypoxia-induced toxicity in H9c2 cardiomyocytes and structural elucidation as 5-LOX inhibitors 65
Further studies on ethyl 5-hydroxy-indole-3-carboxylate scaffold: Design, synthesis and evaluation of 2-phenylthiomethyl-indole derivatives as efficient inhibitors of human 5-lipoxygenase 63
Recent advances in the search for novel 5-lipoxygenase inhibitors for the treatment of asthma 63
Is molecular size a discriminating factor in hyaluronan interaction with human cells? 62
In vitro antiviral and immunomodulatory activity of arbidol and structurally related derivatives in herpes simplex virus type 1-infected human keratinocytes (HaCat). 59
Optimization of hyaluronan-based eye drop formulations 59
Circulating Regulatory T-Cells in Monoclonal Gammopathies of Uncertain Significance and Multiple Myeloma: In Search of a Role 57
A hydroquinone-based derivative elicits apoptosis and autophagy via activating a ros-dependent unfolded protein response in human glioblastoma 57
Active methylene compounds in a very effective approach to 3-substituted isobenzofuranones through tandem aldol/lactonization reactions 55
Exploring the role of chloro and methyl substitutions in 2- phenylthiomethyl-benzoindole derivatives for 5-LOX enzyme inhibition 55
Anti-inflammatory drugs as anticancer agents 54
Design of inhibitors of influenza virus membrane fusion: Synthesis, structure-activity relationship and in vitro antiviral activity of a novel indole series. 53
Formulation and characterization of solid lipid nanoparticles loading rf22-c, a potent and selective 5-lo inhibitor, in a monocrotaline-induced model of pulmonary hypertension 52
Cascade reactions of glycine Schiff bases and chiral phase transfer catalysts in the synthesis of alpha-amino acids 3-substituted phthalides or isoindolinones 51
Cyclohexa-2,5-diene-1,4-dione-based antiproliferative agents: design, synthesis, and cytotoxic evaluation 50
Evaluation of alternative strategies to optimize ketorolac transdermal delivery 50
Antioxidant activity of diphenylpropionamide derivatives: Synthesis, biological evaluation and computational analysis 49
Design, synthesis, biophysical and biological studies of trisubstituted naphthalimides as G-quadruplex ligands 48
2,3-Dihydro-1,2-Diphenyl-substituted 4H-Pyridinone Derivatives as New Anti Flaviviridae Inhibitors 48
Circulating Regulatory T-Cells in Monoclonal Gammopathies of Uncertain Significance and Multiple Myeloma: In Search of a Role 48
Synthesis and cytotoxic activity of new β-carboline derivatives 47
The aldol addition of readily enolizable 1,3-dicarbonyl compounds to 2-cyanobenzaldehyde in the synthesis of novel 3-substituted isoindolinones 45
Bifunctional phase-transfer catalysis in the asymmetric synthesis of biologically active isoindolinones 42
Synthesis and preliminary biological evaluation of 2 '-substituted 2-(3 '-carboxybicyclo[1.1.1]-pentyl)glycine derivatives as group I selective metabotropic glutamate receptor ligands 41
Design, synthesis and biological evaluation of novel bicyclo[1.1.1] pentane-based omega-acidic amino acids as glutamate receptors ligands 41
3-Carboxylate Substituted Isoindolinones in K2CO3-Catalyzed Michael Reactions 40
Nociceptin/Orphanin Fq in inflammation and remodeling of the small airways in experimental model of airway hyperresponsiveness 40
A New Approach to Di- and Tetrasubstituted 2,3-Dihydropyridin-4(1H)-ones through Aza-Diels-Alder Reaction Promoted by Silicon Tetrachloride 39
Binding of harmine derivatives to DNA: A Spectroscopic investigation 39
Elucidation of the molecular mechanism and the efficacy in vivo of a novel 1,4-benzoquinone that inhibits 5-lipoxygenase. 37
Potent inhibition of human 5-lipoxygenase and microsomal prostaglandin E-2 synthase-1 by the anti-carcinogenic and anti-inflammatory agent embelin 37
Synthesis and antiproliferative properties of N-3/8-disubstituted 3,8-diazabicyclo[3.2.1]octane analogues of 3,8-bis[2-(3,4,5-trimethoxyphenyl)pyridin-4-yl]methyl-piperazine 37
A systematic study on the use of different organocatalytic activation modes for asymmetric conjugated addition reactions of isoindolinones 36
Synthesis of beta-hydroxymalonates: the direct aldol addition of malonates to aldehydes in the presence of SiCl4 and i-Pr2EtN 35
Discovery of Novel multi-target Indole-based Derivatives as Potent and Selective Inhibitors of Chikungunya Virus Replication 35
Synthesis, physicochemical properties and in vitro permeation studies of new ketorolac ester derivatives. 34
A novel pyrimidine tetrad contributing to stabilize tetramolecular G-quadruplex structures 34
Discovery and biological evaluation of novel 1,4-benzoquinone and related resorcinol derivatives that inhibit 5-lipoxygenase 33
Molecular mechanism involved in the transport of a prodrug dopamine glycosyl conjugate 33
Optimization of benzoquinone and hydroquinone derivatives as potent inhibitors of human 5-lipoxygenase 33
Diabetes mellitus and male aging: Pharmacotherapeutics and clinical implications 33
New chelating agents for Cu(II), Fe(III), Al(III), and Zn(II) based on beta-diketonate-3-substituted phthalide (isobenzofuranone) and isoindolinone 32
Synthesis and Reactivity of the 3-Substituted Isoindolinone Framework to Assemble Highly Functionalized Related Structures 32
Multi-component, regio-selective aldol addition of beta-ketoesters to aldehydes: scope and applications 32
Improved thrombin binding aptamer analogues containing inversion of polarity sites: Structural effects of extra-residues at the ends 32
Organocatalytic asymmetric hydroxymethylation of isoindolinones with paraformaldehyde 32
Diastereoselectivity in the alkylation of 4-fluoroproline methyl esters 31
Structure-based design, synthesis and preliminary anti-inflammatory activity of bolinaquinone analogues 31
The Introduction of Inversion of Polarity Sites in DNA G-Quadruplex Structures: Effects and Perspectives 31
Synthesis and pharmacological evaluation of functionalized isoindolinones on GABA-activated chloride currents in rat cerebellum granule cells in culture 31
Synthesis and biological evaluation of (2S)-and (2R)-2-(3 '-phosphonobicyclo[1.1.1]pentyl)glycines as novel group III selective metabotropic glutamate receptor ligands 30
Molecular modelling studies, synthesis and biological activity of a series of novel bisnaphthalimides and their development as new DNA topoisomerase II inhibitors 30
Formulation of Solid Lipid Nanoparticles Loaded with Nociceptin/Orphanin FQ (N/OFQ) and Characterization in a Murine Model of Airway Hyperresponsiveness 29
Trimethylchlorosilane and Silicon Tetrachloride in Two Novel Methodologies for the Efficient and Mild Aldol Addition of beta-Keto Esters and Malonates to Aldehydes 29
Natural compounds in anti-leukaemic therapy: a review 28
Phenolics from Castanea sativa leaves and their effects on UVB-induced damage 26
Design and synthesis of functionalized 4-aryl-Catechol derivatives as new antinflammatory agents with in vivo efficacy 25
The 5-lipoxygenase inhibitor RF-22c potently suppresses leukotriene biosynthesis in cellulo and blocks bronchoconstriction and inflammation in vivo 11
Totale 3.089
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Categoria #
all - tutte 13.786
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 13.786
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020303 0 0 0 0 65 22 93 37 18 26 28 14
2020/2021450 11 4 58 31 67 24 71 53 12 51 65 3
2021/2022420 12 7 3 10 134 6 4 14 14 66 25 125
2022/2023721 80 22 22 34 76 50 1 28 370 6 18 14
2023/2024263 19 8 10 5 109 11 3 4 12 3 13 66
2024/2025187 2 15 1 11 158 0 0 0 0 0 0 0
Totale 3.089