IRIS
FILOSA, Rosanna
 Distribuzione geografica
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Continente #
EU - Europa 1.408
NA - Nord America 1.334
AS - Asia 584
SA - Sud America 66
AF - Africa 3
OC - Oceania 1
Totale 3.396
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Nazione #
US - Stati Uniti d'America 1.325
IE - Irlanda 428
IT - Italia 287
UA - Ucraina 217
SG - Singapore 192
HK - Hong Kong 182
GB - Regno Unito 165
CN - Cina 130
DE - Germania 94
BR - Brasile 61
GR - Grecia 60
FI - Finlandia 52
FR - Francia 50
TR - Turchia 39
KR - Corea 14
BE - Belgio 13
SE - Svezia 11
CA - Canada 8
RU - Federazione Russa 8
NL - Olanda 6
CZ - Repubblica Ceca 5
AT - Austria 4
VN - Vietnam 4
ID - Indonesia 3
MY - Malesia 3
PK - Pakistan 3
PL - Polonia 3
CL - Cile 2
ES - Italia 2
IN - India 2
IQ - Iraq 2
IR - Iran 2
UZ - Uzbekistan 2
ZA - Sudafrica 2
AE - Emirati Arabi Uniti 1
AU - Australia 1
BD - Bangladesh 1
BO - Bolivia 1
CH - Svizzera 1
EC - Ecuador 1
EG - Egitto 1
JP - Giappone 1
KZ - Kazakistan 1
MD - Moldavia 1
MX - Messico 1
NP - Nepal 1
RS - Serbia 1
TJ - Tagikistan 1
VE - Venezuela 1
Totale 3.396
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Città #
Dublin 428
Jacksonville 324
Santa Clara 220
Hong Kong 182
Chandler 162
Princeton 61
Medford 60
Ann Arbor 58
Roxbury 58
Singapore 53
Caserta 47
Beijing 41
Bremen 32
Woodbridge 31
Wilmington 24
Mountain View 22
Naples 20
Napoli 16
Des Moines 15
Düsseldorf 15
Jinan 14
Brussels 13
Seoul 13
Nuremberg 12
Nanjing 11
New York 11
Campodarsego 10
Boardman 9
Dearborn 9
Norwalk 8
San Mateo 7
Arzano 6
Auburn Hills 6
Monte Compatri 6
Changsha 5
Latina 5
Novokuznetsk 5
Ottawa 5
Redwood City 5
Salerno 5
Segrate 5
Zhengzhou 5
Ashburn 4
Brno 4
Hefei 4
Kunming 4
Rome 4
Afragola 3
Amsterdam 3
Cambridge 3
Fortaleza 3
Hebei 3
Houston 3
Jakarta 3
Los Angeles 3
Marcianise 3
Matera 3
Munich 3
Shenyang 3
Venice 3
Aversa 2
Benevento 2
Calcinato 2
Contagem 2
Dong Ket 2
Elora 2
Frattaminore 2
Grafing 2
Guangzhou 2
Hangzhou 2
Jequié 2
Johannesburg 2
London 2
Milan 2
Nanchang 2
Nürnberg 2
Paterno 2
Porto Alegre 2
San Felice A Cancello 2
San Mango 2
Santiago 2
Scottsdale 2
Siderno 2
Sorocaba 2
São Paulo 2
Tashkent 2
The Dalles 2
Tân An 2
Washington 2
Wuhan 2
Alpinópolis 1
Amalfi 1
Anshan 1
Arujá 1
Athens 1
Bari 1
Belgrade 1
Belo Horizonte 1
Bethesda 1
Bonea 1
Totale 2.173
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Nome #
Derivati 3-eteroarilfenolici come nuovi potenti inibitori della 5-lipossigenasi 190
The 1,4 benzoquinone-featured 5-lipoxygenase inhibitor RF-Id induces apoptotic death through downregulation of IAPs in human glioblastoma cells 99
Role of adiponectin in sphingosine-1-phosphate induced airway hyperresponsiveness and inflammation 91
1-methoxy-canthin-6-one and related β-carbolines: From natural compound to synthesis and biological activities 85
Hyaluronan hydrogels with a low degree of modification as scaffolds for cartilage engineering 82
Structural insight into the optimization of ethyl 5-hydroxybenzo[g] indol-3-carboxylates and their bioisosteric analogues as 5-LO/mPGES-1 dual inhibitors able to suppress inflammation 79
Structure-activity relationship study of arbidol derivatives as inhibitors of chikungunya virus replication 76
Recent advances in the search for novel 5-lipoxygenase inhibitors for the treatment of asthma 74
Novel series of benzoquinones with high potency against 5-lipoxygenase in human polymorphonuclear leukocytes 72
Protective effect of piceatannol and bioactive stilbene derivatives against hypoxia-induced toxicity in H9c2 cardiomyocytes and structural elucidation as 5-LOX inhibitors 72
Further studies on ethyl 5-hydroxy-indole-3-carboxylate scaffold: Design, synthesis and evaluation of 2-phenylthiomethyl-indole derivatives as efficient inhibitors of human 5-lipoxygenase 71
Optimization of hyaluronan-based eye drop formulations 71
Anti-inflammatory drugs as anticancer agents 71
In vitro antiviral and immunomodulatory activity of arbidol and structurally related derivatives in herpes simplex virus type 1-infected human keratinocytes (HaCat). 70
Is molecular size a discriminating factor in hyaluronan interaction with human cells? 70
Circulating Regulatory T-Cells in Monoclonal Gammopathies of Uncertain Significance and Multiple Myeloma: In Search of a Role 68
Design of inhibitors of influenza virus membrane fusion: Synthesis, structure-activity relationship and in vitro antiviral activity of a novel indole series. 68
A hydroquinone-based derivative elicits apoptosis and autophagy via activating a ros-dependent unfolded protein response in human glioblastoma 67
Active methylene compounds in a very effective approach to 3-substituted isobenzofuranones through tandem aldol/lactonization reactions 61
Exploring the role of chloro and methyl substitutions in 2- phenylthiomethyl-benzoindole derivatives for 5-LOX enzyme inhibition 60
Cyclohexa-2,5-diene-1,4-dione-based antiproliferative agents: design, synthesis, and cytotoxic evaluation 59
Cascade reactions of glycine Schiff bases and chiral phase transfer catalysts in the synthesis of alpha-amino acids 3-substituted phthalides or isoindolinones 58
Formulation and characterization of solid lipid nanoparticles loading rf22-c, a potent and selective 5-lo inhibitor, in a monocrotaline-induced model of pulmonary hypertension 58
Evaluation of alternative strategies to optimize ketorolac transdermal delivery 57
Antioxidant activity of diphenylpropionamide derivatives: Synthesis, biological evaluation and computational analysis 55
Circulating Regulatory T-Cells in Monoclonal Gammopathies of Uncertain Significance and Multiple Myeloma: In Search of a Role 55
2,3-Dihydro-1,2-Diphenyl-substituted 4H-Pyridinone Derivatives as New Anti Flaviviridae Inhibitors 54
Synthesis and cytotoxic activity of new β-carboline derivatives 53
Design, synthesis, biophysical and biological studies of trisubstituted naphthalimides as G-quadruplex ligands 53
Bifunctional phase-transfer catalysis in the asymmetric synthesis of biologically active isoindolinones 51
3-Carboxylate Substituted Isoindolinones in K2CO3-Catalyzed Michael Reactions 49
The aldol addition of readily enolizable 1,3-dicarbonyl compounds to 2-cyanobenzaldehyde in the synthesis of novel 3-substituted isoindolinones 49
A systematic study on the use of different organocatalytic activation modes for asymmetric conjugated addition reactions of isoindolinones 49
Binding of harmine derivatives to DNA: A Spectroscopic investigation 49
A New Approach to Di- and Tetrasubstituted 2,3-Dihydropyridin-4(1H)-ones through Aza-Diels-Alder Reaction Promoted by Silicon Tetrachloride 47
Design, synthesis and biological evaluation of novel bicyclo[1.1.1] pentane-based omega-acidic amino acids as glutamate receptors ligands 47
Elucidation of the molecular mechanism and the efficacy in vivo of a novel 1,4-benzoquinone that inhibits 5-lipoxygenase. 46
Potent inhibition of human 5-lipoxygenase and microsomal prostaglandin E-2 synthase-1 by the anti-carcinogenic and anti-inflammatory agent embelin 46
Nociceptin/Orphanin Fq in inflammation and remodeling of the small airways in experimental model of airway hyperresponsiveness 46
Synthesis and preliminary biological evaluation of 2 '-substituted 2-(3 '-carboxybicyclo[1.1.1]-pentyl)glycine derivatives as group I selective metabotropic glutamate receptor ligands 45
A novel pyrimidine tetrad contributing to stabilize tetramolecular G-quadruplex structures 45
Diabetes mellitus and male aging: Pharmacotherapeutics and clinical implications 43
Synthesis and antiproliferative properties of N-3/8-disubstituted 3,8-diazabicyclo[3.2.1]octane analogues of 3,8-bis[2-(3,4,5-trimethoxyphenyl)pyridin-4-yl]methyl-piperazine 41
Design and synthesis of functionalized 4-aryl-Catechol derivatives as new antinflammatory agents with in vivo efficacy 40
Discovery and biological evaluation of novel 1,4-benzoquinone and related resorcinol derivatives that inhibit 5-lipoxygenase 40
Optimization of benzoquinone and hydroquinone derivatives as potent inhibitors of human 5-lipoxygenase 40
Phenolics from Castanea sativa leaves and their effects on UVB-induced damage 40
Formulation of Solid Lipid Nanoparticles Loaded with Nociceptin/Orphanin FQ (N/OFQ) and Characterization in a Murine Model of Airway Hyperresponsiveness 39
Synthesis of beta-hydroxymalonates: the direct aldol addition of malonates to aldehydes in the presence of SiCl4 and i-Pr2EtN 39
Discovery of Novel multi-target Indole-based Derivatives as Potent and Selective Inhibitors of Chikungunya Virus Replication 39
Improved thrombin binding aptamer analogues containing inversion of polarity sites: Structural effects of extra-residues at the ends 39
Synthesis and pharmacological evaluation of functionalized isoindolinones on GABA-activated chloride currents in rat cerebellum granule cells in culture 39
Molecular mechanism involved in the transport of a prodrug dopamine glycosyl conjugate 38
Synthesis, physicochemical properties and in vitro permeation studies of new ketorolac ester derivatives. 38
Synthesis and Reactivity of the 3-Substituted Isoindolinone Framework to Assemble Highly Functionalized Related Structures 37
Organocatalytic asymmetric hydroxymethylation of isoindolinones with paraformaldehyde 37
New chelating agents for Cu(II), Fe(III), Al(III), and Zn(II) based on beta-diketonate-3-substituted phthalide (isobenzofuranone) and isoindolinone 36
Structure-based design, synthesis and preliminary anti-inflammatory activity of bolinaquinone analogues 36
Multi-component, regio-selective aldol addition of beta-ketoesters to aldehydes: scope and applications 36
The Introduction of Inversion of Polarity Sites in DNA G-Quadruplex Structures: Effects and Perspectives 36
Diastereoselectivity in the alkylation of 4-fluoroproline methyl esters 35
Molecular modelling studies, synthesis and biological activity of a series of novel bisnaphthalimides and their development as new DNA topoisomerase II inhibitors 35
Synthesis and biological evaluation of (2S)-and (2R)-2-(3 '-phosphonobicyclo[1.1.1]pentyl)glycines as novel group III selective metabotropic glutamate receptor ligands 34
Trimethylchlorosilane and Silicon Tetrachloride in Two Novel Methodologies for the Efficient and Mild Aldol Addition of beta-Keto Esters and Malonates to Aldehydes 33
Natural compounds in anti-leukaemic therapy: a review 33
The 5-lipoxygenase inhibitor RF-22c potently suppresses leukotriene biosynthesis in cellulo and blocks bronchoconstriction and inflammation in vivo 18
Lower pain, less itching, and faster healing after ultrasound scalpel-assisted hemorrhoidectomy using an intimate cleaner containing chlorhexidine, acid hyaluronic acid, and natural anti-inflammatories: a multicenter observational case-control study 12
Totale 3.601
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Categoria #
all - tutte 16.670
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 16.670
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/202042 0 0 0 0 0 0 0 0 0 0 28 14
2020/2021450 11 4 58 31 67 24 71 53 12 51 65 3
2021/2022420 12 7 3 10 134 6 4 14 14 66 25 125
2022/2023721 80 22 22 34 76 50 1 28 370 6 18 14
2023/2024263 19 8 10 5 109 11 3 4 12 3 13 66
2024/2025699 2 15 1 11 159 105 199 42 86 79 0 0
Totale 3.601