IRIS
FILOSA, Rosanna
 Distribuzione geografica
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Continente #
EU - Europa 3.972
NA - Nord America 1.486
AS - Asia 1.206
SA - Sud America 283
AF - Africa 21
OC - Oceania 2
Totale 6.970
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Nazione #
RU - Federazione Russa 2.517
US - Stati Uniti d'America 1.464
IE - Irlanda 428
SG - Singapore 425
CN - Cina 297
IT - Italia 292
BR - Brasile 230
UA - Ucraina 218
HK - Hong Kong 189
GB - Regno Unito 168
DE - Germania 115
VN - Vietnam 105
KR - Corea 71
GR - Grecia 60
FI - Finlandia 59
FR - Francia 52
TR - Turchia 41
AR - Argentina 22
IN - India 21
CA - Canada 15
BE - Belgio 13
SE - Svezia 13
JP - Giappone 12
BD - Bangladesh 9
EC - Ecuador 9
ZA - Sudafrica 8
CO - Colombia 7
ID - Indonesia 7
NL - Olanda 7
PL - Polonia 7
AT - Austria 5
CZ - Repubblica Ceca 5
MX - Messico 5
PK - Pakistan 5
CL - Cile 4
IQ - Iraq 4
IR - Iran 3
KE - Kenya 3
MY - Malesia 3
PE - Perù 3
TN - Tunisia 3
UZ - Uzbekistan 3
VE - Venezuela 3
AE - Emirati Arabi Uniti 2
BO - Bolivia 2
BY - Bielorussia 2
CH - Svizzera 2
DZ - Algeria 2
ES - Italia 2
KW - Kuwait 2
MA - Marocco 2
NP - Nepal 2
PY - Paraguay 2
RO - Romania 2
SN - Senegal 2
AL - Albania 1
AU - Australia 1
BN - Brunei Darussalam 1
EG - Egitto 1
GT - Guatemala 1
HN - Honduras 1
HR - Croazia 1
JO - Giordania 1
KZ - Kazakistan 1
LV - Lettonia 1
MD - Moldavia 1
PW - Palau 1
RS - Serbia 1
SA - Arabia Saudita 1
TJ - Tagikistan 1
UY - Uruguay 1
Totale 6.970
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Città #
Moscow 831
Dublin 428
Jacksonville 325
Santa Clara 220
Hong Kong 189
Chandler 162
Singapore 158
Beijing 70
Seoul 70
Princeton 61
Medford 60
Ann Arbor 58
Roxbury 58
Caserta 47
Ho Chi Minh City 47
Ashburn 33
Bremen 32
Woodbridge 31
Wilmington 25
Hanoi 24
Munich 23
Mountain View 22
Hefei 21
Naples 21
Dallas 18
Jinan 16
Napoli 16
New York 16
Bengaluru 15
Des Moines 15
Düsseldorf 15
São Paulo 14
Brussels 13
Nuremberg 13
The Dalles 13
Los Angeles 12
Nanjing 11
Campodarsego 10
Boardman 9
Dearborn 9
Norwalk 8
Rio de Janeiro 7
San Mateo 7
Turku 7
Arzano 6
Auburn Hills 6
Changsha 6
Fortaleza 6
Guayaquil 6
Monte Compatri 6
Tianjin 6
Brasília 5
Jakarta 5
Johannesburg 5
Latina 5
Novokuznetsk 5
Ottawa 5
Redwood City 5
Salerno 5
Segrate 5
Zhengzhou 5
Amsterdam 4
Belo Horizonte 4
Brno 4
Can Tho 4
Chicago 4
Guangzhou 4
Kunming 4
London 4
Montreal 4
Rome 4
Tokyo 4
Warsaw 4
Afragola 3
Boston 3
Brooklyn 3
Buenos Aires 3
Cambridge 3
Curitiba 3
Guarulhos 3
Haiphong 3
Hangzhou 3
Hebei 3
Houston 3
Lima 3
Marcianise 3
Matera 3
Milan 3
Nairobi 3
Phoenix 3
Porto Alegre 3
San Francisco 3
Santiago 3
Santo André 3
Shanghai 3
Shenyang 3
São José dos Campos 3
Tashkent 3
Thái Nguyên 3
Uberlândia 3
Totale 3.481
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Nome #
Derivati 3-eteroarilfenolici come nuovi potenti inibitori della 5-lipossigenasi 259
A hydroquinone-based derivative elicits apoptosis and autophagy via activating a ros-dependent unfolded protein response in human glioblastoma 160
The 1,4 benzoquinone-featured 5-lipoxygenase inhibitor RF-Id induces apoptotic death through downregulation of IAPs in human glioblastoma cells 158
Anti-inflammatory drugs as anticancer agents 158
1-methoxy-canthin-6-one and related β-carbolines: From natural compound to synthesis and biological activities 152
Role of adiponectin in sphingosine-1-phosphate induced airway hyperresponsiveness and inflammation 138
Formulation and characterization of solid lipid nanoparticles loading rf22-c, a potent and selective 5-lo inhibitor, in a monocrotaline-induced model of pulmonary hypertension 138
In vitro antiviral and immunomodulatory activity of arbidol and structurally related derivatives in herpes simplex virus type 1-infected human keratinocytes (HaCat). 136
Design of inhibitors of influenza virus membrane fusion: Synthesis, structure-activity relationship and in vitro antiviral activity of a novel indole series. 135
Cyclohexa-2,5-diene-1,4-dione-based antiproliferative agents: design, synthesis, and cytotoxic evaluation 135
Structural insight into the optimization of ethyl 5-hydroxybenzo[g] indol-3-carboxylates and their bioisosteric analogues as 5-LO/mPGES-1 dual inhibitors able to suppress inflammation 134
Structure-activity relationship study of arbidol derivatives as inhibitors of chikungunya virus replication 129
Circulating Regulatory T-Cells in Monoclonal Gammopathies of Uncertain Significance and Multiple Myeloma: In Search of a Role 129
Hyaluronan hydrogels with a low degree of modification as scaffolds for cartilage engineering 128
Design and synthesis of functionalized 4-aryl-Catechol derivatives as new antinflammatory agents with in vivo efficacy 126
Novel series of benzoquinones with high potency against 5-lipoxygenase in human polymorphonuclear leukocytes 125
Active methylene compounds in a very effective approach to 3-substituted isobenzofuranones through tandem aldol/lactonization reactions 125
Cascade reactions of glycine Schiff bases and chiral phase transfer catalysts in the synthesis of alpha-amino acids 3-substituted phthalides or isoindolinones 125
Optimization of hyaluronan-based eye drop formulations 123
Circulating Regulatory T-Cells in Monoclonal Gammopathies of Uncertain Significance and Multiple Myeloma: In Search of a Role 122
Is molecular size a discriminating factor in hyaluronan interaction with human cells? 121
Bifunctional phase-transfer catalysis in the asymmetric synthesis of biologically active isoindolinones 120
Recent advances in the search for novel 5-lipoxygenase inhibitors for the treatment of asthma 120
Antioxidant activity of diphenylpropionamide derivatives: Synthesis, biological evaluation and computational analysis 118
Binding of harmine derivatives to DNA: A Spectroscopic investigation 118
Formulation of Solid Lipid Nanoparticles Loaded with Nociceptin/Orphanin FQ (N/OFQ) and Characterization in a Murine Model of Airway Hyperresponsiveness 117
A systematic study on the use of different organocatalytic activation modes for asymmetric conjugated addition reactions of isoindolinones 115
2,3-Dihydro-1,2-Diphenyl-substituted 4H-Pyridinone Derivatives as New Anti Flaviviridae Inhibitors 112
Further studies on ethyl 5-hydroxy-indole-3-carboxylate scaffold: Design, synthesis and evaluation of 2-phenylthiomethyl-indole derivatives as efficient inhibitors of human 5-lipoxygenase 110
A New Approach to Di- and Tetrasubstituted 2,3-Dihydropyridin-4(1H)-ones through Aza-Diels-Alder Reaction Promoted by Silicon Tetrachloride 109
Protective effect of piceatannol and bioactive stilbene derivatives against hypoxia-induced toxicity in H9c2 cardiomyocytes and structural elucidation as 5-LOX inhibitors 109
Evaluation of alternative strategies to optimize ketorolac transdermal delivery 108
Design, synthesis and biological evaluation of novel bicyclo[1.1.1] pentane-based omega-acidic amino acids as glutamate receptors ligands 106
A novel pyrimidine tetrad contributing to stabilize tetramolecular G-quadruplex structures 106
3-Carboxylate Substituted Isoindolinones in K2CO3-Catalyzed Michael Reactions 105
Phenolics from Castanea sativa leaves and their effects on UVB-induced damage 102
Exploring the role of chloro and methyl substitutions in 2- phenylthiomethyl-benzoindole derivatives for 5-LOX enzyme inhibition 100
Synthesis and cytotoxic activity of new β-carboline derivatives 99
Nociceptin/Orphanin Fq in inflammation and remodeling of the small airways in experimental model of airway hyperresponsiveness 93
The aldol addition of readily enolizable 1,3-dicarbonyl compounds to 2-cyanobenzaldehyde in the synthesis of novel 3-substituted isoindolinones 92
Optimization of benzoquinone and hydroquinone derivatives as potent inhibitors of human 5-lipoxygenase 91
Potent inhibition of human 5-lipoxygenase and microsomal prostaglandin E-2 synthase-1 by the anti-carcinogenic and anti-inflammatory agent embelin 89
Synthesis of beta-hydroxymalonates: the direct aldol addition of malonates to aldehydes in the presence of SiCl4 and i-Pr2EtN 89
Lower pain, less itching, and faster healing after ultrasound scalpel-assisted hemorrhoidectomy using an intimate cleaner containing chlorhexidine, acid hyaluronic acid, and natural anti-inflammatories: a multicenter observational case-control study 87
Design, synthesis, biophysical and biological studies of trisubstituted naphthalimides as G-quadruplex ligands 87
Elucidation of the molecular mechanism and the efficacy in vivo of a novel 1,4-benzoquinone that inhibits 5-lipoxygenase. 84
Synthesis and preliminary biological evaluation of 2 '-substituted 2-(3 '-carboxybicyclo[1.1.1]-pentyl)glycine derivatives as group I selective metabotropic glutamate receptor ligands 83
Discovery of Novel multi-target Indole-based Derivatives as Potent and Selective Inhibitors of Chikungunya Virus Replication 83
Synthesis and antiproliferative properties of N-3/8-disubstituted 3,8-diazabicyclo[3.2.1]octane analogues of 3,8-bis[2-(3,4,5-trimethoxyphenyl)pyridin-4-yl]methyl-piperazine 81
Synthesis and pharmacological evaluation of functionalized isoindolinones on GABA-activated chloride currents in rat cerebellum granule cells in culture 79
Structure-based design, synthesis and preliminary anti-inflammatory activity of bolinaquinone analogues 78
Discovery and biological evaluation of novel 1,4-benzoquinone and related resorcinol derivatives that inhibit 5-lipoxygenase 77
Synthesis and biological evaluation of (2S)-and (2R)-2-(3 '-phosphonobicyclo[1.1.1]pentyl)glycines as novel group III selective metabotropic glutamate receptor ligands 77
Molecular mechanism involved in the transport of a prodrug dopamine glycosyl conjugate 77
Natural compounds in anti-leukaemic therapy: a review 77
Improved thrombin binding aptamer analogues containing inversion of polarity sites: Structural effects of extra-residues at the ends 76
Synthesis and Reactivity of the 3-Substituted Isoindolinone Framework to Assemble Highly Functionalized Related Structures 75
Molecular modelling studies, synthesis and biological activity of a series of novel bisnaphthalimides and their development as new DNA topoisomerase II inhibitors 75
Diabetes mellitus and male aging: Pharmacotherapeutics and clinical implications 75
New chelating agents for Cu(II), Fe(III), Al(III), and Zn(II) based on beta-diketonate-3-substituted phthalide (isobenzofuranone) and isoindolinone 74
Organocatalytic asymmetric hydroxymethylation of isoindolinones with paraformaldehyde 74
Trimethylchlorosilane and Silicon Tetrachloride in Two Novel Methodologies for the Efficient and Mild Aldol Addition of beta-Keto Esters and Malonates to Aldehydes 73
Diastereoselectivity in the alkylation of 4-fluoroproline methyl esters 73
Synthesis, physicochemical properties and in vitro permeation studies of new ketorolac ester derivatives. 73
Multi-component, regio-selective aldol addition of beta-ketoesters to aldehydes: scope and applications 68
The Introduction of Inversion of Polarity Sites in DNA G-Quadruplex Structures: Effects and Perspectives 68
The 5-lipoxygenase inhibitor RF-22c potently suppresses leukotriene biosynthesis in cellulo and blocks bronchoconstriction and inflammation in vivo 67
Evaluation of molecular mechanisms of (Z)-3-(pentadec-10′-enyl)-catechol (litreol) and synthetic derivatives as inhibitors of human leukotriene biosynthesis 51
Totale 7.176
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Categoria #
all - tutte 24.237
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 24.237
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021279 0 0 0 0 0 24 71 53 12 51 65 3
2021/2022420 12 7 3 10 134 6 4 14 14 66 25 125
2022/2023721 80 22 22 34 76 50 1 28 370 6 18 14
2023/2024263 19 8 10 5 109 11 3 4 12 3 13 66
2024/2025826 2 15 1 11 159 105 199 42 86 79 62 65
2025/20263.448 116 119 190 289 349 2.385 0 0 0 0 0 0
Totale 7.176