IRIS
MAIONE, Sabatino
 Distribuzione geografica
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Continente #
NA - Nord America 7.063
EU - Europa 6.147
AS - Asia 1.794
SA - Sud America 17
OC - Oceania 6
Continente sconosciuto - Info sul continente non disponibili 5
Totale 15.032
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Nazione #
US - Stati Uniti d'America 7.051
IE - Irlanda 2.082
CN - Cina 1.465
UA - Ucraina 977
IT - Italia 805
GB - Regno Unito 764
DE - Germania 642
SE - Svezia 308
FI - Finlandia 252
TR - Turchia 252
GR - Grecia 174
FR - Francia 62
BE - Belgio 37
VN - Vietnam 28
CA - Canada 12
BR - Brasile 11
NL - Olanda 11
ES - Italia 10
IN - India 8
JP - Giappone 7
LB - Libano 7
TW - Taiwan 7
KR - Corea 6
PL - Polonia 6
EU - Europa 5
DK - Danimarca 4
IR - Iran 4
NZ - Nuova Zelanda 4
CL - Cile 3
HK - Hong Kong 3
AU - Australia 2
EC - Ecuador 2
MK - Macedonia 2
RO - Romania 2
RU - Federazione Russa 2
AE - Emirati Arabi Uniti 1
AL - Albania 1
AR - Argentina 1
BD - Bangladesh 1
CH - Svizzera 1
CZ - Repubblica Ceca 1
HU - Ungheria 1
IL - Israele 1
IM - Isola di Man 1
KH - Cambogia 1
MC - Monaco 1
PH - Filippine 1
PK - Pakistan 1
RS - Serbia 1
SG - Singapore 1
Totale 15.032
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Città #
Dublin 2.075
Chandler 1.461
Jacksonville 1.436
Beijing 362
Ashburn 280
Princeton 280
Dearborn 263
Boardman 255
Medford 249
Bremen 222
Ann Arbor 205
Wilmington 193
Hefei 168
San Mateo 162
Woodbridge 158
Nanjing 154
Roxbury 153
Caserta 134
Kunming 120
New York 107
Naples 94
Jinan 92
Cava 70
Cambridge 66
Guangzhou 53
Des Moines 52
Düsseldorf 50
Nanchang 50
Napoli 48
Hebei 43
Mugnano di Napoli 42
Houston 40
Shenyang 40
Brussels 37
Zhengzhou 37
Redwood City 35
Auburn Hills 31
Norwalk 31
Mountain View 29
Dong Ket 26
Ningbo 23
Rome 22
Venice 21
Los Angeles 19
Hangzhou 18
Shaoxing 17
Lanzhou 15
Milan 15
Changsha 14
Fuzhou 14
Helsinki 14
Baotou 13
Chengdu 13
Hanover 13
Chongqing 12
Fairfield 12
Xian 12
Tianjin 11
Shanghai 10
Taizhou 10
Wuhan 10
Grafing 9
Haikou 9
Lappeenranta 8
Chaoyang 7
Falls Church 7
Paris 7
Santa Maria Capua Vetere 7
Taipei 7
Tappahannock 7
Wenzhou 7
Aiello del Sabato 6
Jinhua 6
London 6
Nanning 6
Quzhou 6
Siena 6
Aversa 5
Battipaglia 5
Brusciano 5
Campinas 5
Guiyang 5
Huzhou 5
Izmir 5
L'aquila 5
Mcallen 5
Modena 5
Pioltello 5
Seattle 5
Taiyuan 5
Altamura 4
Elora 4
Frederiksberg 4
Harbin 4
Madrid 4
Monza 4
Munich 4
Parma 4
Rockville 4
Amsterdam 3
Totale 9.926
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Nome #
SOSTITUZIONE BIOISOSTERICA DEL GRUPPO AMMIDICO DI 4-CHINOLON-3-CARBOSSAMIDI6-SOSTITUITE:LIGANDI CB2 POTENTI E SELETTIVI PROVVISTI DI MIGLIOR PROFILO CHIMICO-FISICO . 126
"2-FENIL-IMIDAZO[1,2-B]PIRIDAZINE AD ATTIVITA' ANALGESICA ED ANTIEPILETTICA" 120
COCAINE USE AND EFFECTS Scientific and statistical dossier 107
Cannabinoid receptor 2-63 QQ varianti s associated with severe necroinflammation in chronic epatiti C 106
Cannabinoid receptor 2 as anti-obesity target: inflammation, fat storage and browning modulation. 103
MMPIP, an mGluR7-selective negative allosteric modulator, alleviates pain and normalizes affective and cognitive behavior in neuropathic mice 97
Association between cannabinoid receptor type 2 Q63R variant and oligo/polyarticular juvenile idiopathic arthritis 97
USO DEI BISFOSFONATI PER LA PREPARAZIONE DI FORMULAZIONI FARMACEUTICHE PER IL TRATTAMENTO DEI SINTOMI ASSOCIATI A DOLORE NEUROPATICO 97
D-Aspartate drinking solution alleviates pain and cognitive impairment in neuropathic mice. 97
1-(2′,4′-dichlorophenyl)-6-methyl-N-cyclohexylamine-1,4-dihy droindeno[1,2-c]pyrazole-3-carboxamide, a novel CB2 agonist, alleviates neuropathic pain through functional microglial changes in mice 91
Ultrapotent effects of salvinorin A, a hallucinogenic compound from Salvia divinorum, on LPS-stimulated murine macrophages and its anti-inflammatory action in vivo. 91
Palmitoylethanolamide reduces pain-related behaviors and restores glutamatergic synapses homeostasis in the medial prefrontal cortex of neuropathic mice 90
Chalcone derivatives activate and desensitize the transient receptor potential ankyrin 1 cation channel, subfamily A, member 1 TRPA1 ion channel: structure-activity relationships in vitro and anti-nociceptive and anti-inflammatory activity in vivo 87
1-(2',4'-dichlorophenyl)-6-methyl-N-cyclohexylamine-1,4-dihydroindeno[1,2-c]pyrazole-3-carboxamide, a novel CB2 agonist, alleviates neuropathic pain through functional microglial changes in mice. Neurobiol Dis. 2010 Jan;37(1):177-85. Epub 2009 Oct 3. PubMed PMID: 19804829 86
Profarmaco galattosilato della n-omega-nitro-l-arginina (nagal) ad uso analgesico ed antinfiammatorio con migliori caratteristiche farmacocinetiche e di tollerabilità del farmaco di partenza 84
Cannabinoid receptor 2 Q63R variant could modulate the relationship between childhood obesity and age at menarche 83
The antinociceptive effect of tramadol in the formalin test is mediated by the serotonergic component 83
Endocannabinoid Research Group (ERG), Italy. The endovanilloid/endocannabinoid system: a new potential target for osteoporosis therapy. 83
Neuroimmune-driven neuropathic pain establishment: A focus on gender differences 83
PC1, a non-peptide PKR1-preferring antagonist, reduces pain behavior and spinal neuronal sensitization in neuropathic mice. 79
Dorsal striatum metabotropic glutamate receptor 8 affects nocifensive responses and rostral ventromedial medulla cell activity in neuropathic pain conditions. 79
The antinociceptive effect of 2-chloro-2'-C-methyl-N6-cyclopentyladenosine (2'-Me-CCPA), a highly selective adenosine A1 receptor agonist, in the rat 79
La patologia dolorosa cronica e il problema della ‘oppiofobia’ 78
Age-Related Changes in D-Aspartate Oxidase Promoter Methylation Control Extracellular D-Aspartate Levels and Prevent Precocious Cell Death during Brain Aging 77
Palmitoylethanolamide induces microglia changes associated with increased migration and phagocytic activity: Involvement of the CB2 receptor 77
Blockade of glutamate mGlu5 receptors in a rat model of neuropathic pain prevents early over-expression of pro-apoptotic genes and morphological changes in dorsal horn lamina II 75
Association Between a Polymorphism in Cannabinoid Receptor 2 and Severe Necroinflammation in Patients With Chronic Hepatitis C. 75
Involvement of subtype 1 metabotropic glutamate receptors in apoptosis and caspase-7 over-expression in spinal cord of neuropathic rats 73
Changes in cannabinoid receptor subtype 1 activity and interaction with metabotropic glutamate subtype 5 receptors in the periaqueductal gray-rostral ventromedial medulla pathway in a rodent neuropathic pain model. 73
Palmitoylethanolamide reduces neuropsychiatric behaviors by restoring cortical electrophysiological activity in a mouse model of mild traumatic brain injury 73
The blockade of the transient receptor potential vanilloid type 1 and fatty acid amide hydrolase decreases symptoms and central sequelae in the medial prefrontal cortex of neuropathic rats. 72
Interaction between vanilloid and glutamate receptors in the central modulation of nociception 72
Cannabinoid receptor type 2 functional variant influences liver damage in children with non-alcoholic fatty liver disease 72
EP1 receptor within the ventrolateral periaqueductal grey controls thermonociception and rostral ventromedial medulla cell activity in healthy and neuropathic rat 72
Stealth liposomes encapsulating zoledronic acid: a new opportunity to treat neuropathic pain. 72
null 71
Development and Pharmacological Characterization of Selective Blockers of 2-Arachidonoyl Glycerol Degradation with Efficacy in Rodent Models of Multiple Sclerosis and Pain 71
Design and Synthesis of New Transient Receptor Potential Vanilloid Type-1 (TRPV1) Channel Modulators: Identification, Molecular Modeling Analysis, and Pharmacological Characterization of the N-(4-Hydroxy-3-methoxybenzyl)-4-(thiophen-2-yl)butanamide, a Small Molecule Endowed with Agonist TRPV1 Activity and Protective Effects against Oxidative Stress. 71
Exposure to allergen causes changes in nts neural activities after intratracheal capsaicin application, in endocannabinoid levels and in the glia morphology of nts 71
Selective melatonin MT2 receptor ligands relieve neuropathic pain through modulation of brainstem descending antinociceptive pathways 69
Effects of intra-ventrolateral periaqueductal grey palmitoylethanolamide on thermoceptive threshold and rostral ventromedial medulla cell activity 69
Differential roles of mGlu8 receptors in the regulation of glutamate and gamma-aminobutyric acid release at periaqueductal grey level. Neuropharmacology 69
The cannabinoid receptor type 2 as mediator of mesenchymal stromal cell immunosuppressive properties. 69
Changes in spinal and supraspinal endocannabinoid levels in neuropathic rats 69
Metabotropic glutamate receptor subtype 7 in the dorsal striatum oppositely modulates pain in sham and neuropathic rats 69
Structural insight into the optimization of ethyl 5-hydroxybenzo[g] indol-3-carboxylates and their bioisosteric analogues as 5-LO/mPGES-1 dual inhibitors able to suppress inflammation 69
The 17-β-oestradiol inhibits osteoclast activity by increasing the cannabinoid CB2 receptor expression. 68
Intraperiaqueductal gray glycine and D-serine exert dual effects on rostral ventromedial medulla ON- and OFF-cell activity and thermoceptive threshold in the rat 68
N-acyl-N'-methyl-N-(1,3,3-trimethylbicyclo[2.2.1]hept-2-yl) benzamidines with hypotensive activity 68
D-aspartate modulates nociceptive-specific neuron activity and pain threshold in inflammatory and neuropathic pain condition in mice 67
Characterisation of mGluRs which modulate nociception in the PAG of the mouse 67
5'-Chloro-5'-deoxy-(±)-ENBA, a potent and selective adenosine A(1) receptor agonist, alleviates neuropathic pain in mice through functional glial and microglial changes without affecting motor or cardiovascular functions. Molecules. 67
Elevation of endocannabinoid levels in the ventrolateral periaqueductal grey through inhibition of fatty acid amide hydrolase affects descending nociceptive pathways via both CB1 and TRPV1 receptors. J Pharmacol Exp The 66
Analgesic actions of N-arachidonoyl-serotonin, a fatty acid amide hydrolase inhibitor with antagonistic activity at vanilloid TRPV1 receptors 66
Effects of (S)-3,4-DCPG, an mGlu8 receptor agonist, on inflammatory and neuropathic pain in mice 66
The impact of the CB2-63 polymorphism on the histological presentation of chronic hepatitis B. 66
Characterization of mGluRs which modulate nociception in the PAG of the mouse 66
PKCβII-mediated cross-talk of TRPV1/CB2 modulates the glucocorticoid-induced osteoclast overactivity 66
Salvinorin A reduces mechanical allodynia and spinal neuronal hyperexcitability induced by peripheral formalin injection. 65
Metabotropic glutamate receptor 7: From synaptic function to therapeutic implications 65
The genetic ablation or pharmacological inhibition of TRPV1 signalling is beneficial for the restoration of quiescent osteoclast activity in ovariectomized mice. 64
The A1 adenosine receptor as a new player in microglia physiology 64
Intra-periaqueductal grey microinjections of an imidazo[1,2-b]pyridazine derivative, DM2, affects rostral ventromedial medulla cell activity and shows antinociceptive effect 64
Evidence of muscarinic receptor subtypes in airway smooth muscle of normal volunteers and of chronic obstructive pulmonary disease patients 64
Differential roles of mGlu8 receptors in the regulation of glutamate and gamma-aminobutyric acid release at periaqueductal grey level 64
Excitatory amino acids and cardiovascular apparatus: experimental studies on conscious rats with L-glutamate, N-methyl-D-aspartate, kainate and quisqualate 63
Role of reactive oxygen species and spinal cord apoptotic genes in the development of neuropathic pain 63
Effects of persistent nociception on periaqueductal gray glycine release 63
Effect of Prolonged Moderate Exercise on the Changes of Nonneuronal Cells in Early Myocardial Infarction. 63
CNR2 functional variant (Q63R) influences childhood immune thrombocytopenic purpura. 63
A single subcutaneous injection of ozone prevents allodynia and decreases the over-expression of pro-inflammatory caspases in the orbito-frontal cortex of neuropathic mice 63
The cannabinoid receptor type 2 Q63R variant increases the risk of celiac disease: implication for a novel molecular biomarker and future therapeutic intervention. 63
Hypothalamic paraventricular nucleus involvement in the pressor response to N-methyl-d-aspartic acid in the periaqueductal grey matter 62
Cannabinoid Receptor Type 2, but not Type 1, is Up-Regulated in Peripheral Blood Mononuclear Cells of Children Affected by Autistic Disorders. 62
The endovanilloid/endocannabinoid system: A new potential target for osteoporosis therapy 62
N-methyl-d-aspartate receptors modulate extracellular dopamine concentration and metabolism in rat hippocampus and striatum in vivo 62
Basic and Pharmacological Aspects of Cannabinoid Activity in Nervous and Reproductive Systems 62
Palvanil, a non-pungent capsaicin analogue, inhibits inflammatory and neuropathic pain with little effects on bronchopulmonary function and body temperature. 62
Olanzapine, but not clozapine, increases glutamate release in the prefrontal cortex of freely moving mice by inhibiting D-aspartate oxidase activity. 62
Role of metabotropic glutamate receptor 1 in the basolateral amygdala-driven prefrontal cortical deactivation in inflammatory pain in the rat 61
Intra-Periaqueductal Gray glycine and D-serine exert dual effects on the Rostral Ventromedial Medulla ON and OFF cell activity and thermal threshold in the rat 61
In vitro and in vivo pharmacology of synthetic olivetol- or resorcinol-derived cannabinoid receptor ligands 61
The 17-estradiol inhibits osteoclast activity by increasing the cannabinoid CB2 receptor expression 61
Supraspinal metabotropic glutamate receptor subtype 8: a switch to turn off pain. 60
Contribution of sensory nerves to LPS-induced hyperresponsiveness of human isolated bronchi. 60
Palmitoylethanolamide reduces formalin-induced neuropathic-like behaviour through spinal glial/microglial phenotypical changes in mice 60
The plant cannabinoid D9-tetrahydrocannabivarin can decrease signs of inflammation and inflammatory pain in mice 60
Prenatal and postnatal vanadium exposure in rats: effect on vasomotor reactivity development of pups 60
Investigations on the 4-quinolone-3-carboxylic acid motif part 5: modulation of the physicochemical profile of a set of potent and selective cannabinoid-2 receptor ligands through a bioisosteric approach 60
CB2 and TRPV1 receptors oppositely modulate in vitro human osteoblast activity 60
Group I metabotropic glutamate receptors modulate glutamate and gamma-aminobutyric acid release in the periaqueductal grey of rats. 59
New N-arachidonoylserotonin analogues with potential "dual" mechanism of action against pain 59
Iron overload causes osteoporosis in Thalassemia Major patients through interaction with TRPV1 channels. 59
Gliosis alters expression and uptake of spinal glial amino acid transporters in a mouse neuropathic pain model 59
Antineuropathic profile of N-palmitoylethanolamine in a rat model of oxaliplatin-induced neurotoxicity 59
d-Aspartic acid ameliorates painful and neuropsychiatric changes and reduces β-amyloid Aβ1-42 peptide in a long lasting model of neuropathic pain. 59
Effects of a metabotropic glutamate receptor subtype 7 negative allosteric modulator in the periaqueductal grey on pain responses and rostral ventromedial medulla cell activity in rat 58
Modification of cysteinyl leukotriene receptors expression in capsular contracture: follow-up study and definitive results 58
Antinociceptive effect in mice of intraperitoneal N-methyl-D-aspartate receptor antagonists in the formalin test 58
Effects of imipramine on raphe nuclei and prefrontal cortex extracellular serotonin levels in the rat 58
Totale 7.152
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Categoria #
all - tutte 50.332
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 50.332
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/201981 0 0 0 0 0 0 0 0 0 0 61 20
2019/20202.947 266 254 14 99 258 285 994 453 185 55 69 15
2020/20212.255 205 23 267 109 377 31 365 239 25 288 236 90
2021/20221.929 185 27 17 36 619 30 41 42 74 193 150 515
2022/20234.924 322 80 71 561 623 466 20 368 2.186 48 83 96
2023/20241.444 167 75 69 154 502 148 26 278 11 11 3 0
Totale 15.618