IRIS
MAIONE, Sabatino
 Distribuzione geografica
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Continente #
NA - Nord America 8.228
EU - Europa 6.425
AS - Asia 2.440
SA - Sud America 45
OC - Oceania 6
Continente sconosciuto - Info sul continente non disponibili 5
AF - Africa 1
Totale 17.150
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Nazione #
US - Stati Uniti d'America 8.213
IE - Irlanda 2.065
CN - Cina 1.528
IT - Italia 986
UA - Ucraina 977
GB - Regno Unito 764
DE - Germania 692
SG - Singapore 514
SE - Svezia 308
TR - Turchia 282
FI - Finlandia 267
GR - Grecia 174
FR - Francia 64
BE - Belgio 39
KR - Corea 35
BR - Brasile 34
CZ - Repubblica Ceca 28
VN - Vietnam 28
CA - Canada 15
NL - Olanda 11
ES - Italia 10
AT - Austria 9
IN - India 8
JP - Giappone 7
LB - Libano 7
TW - Taiwan 7
EC - Ecuador 6
HK - Hong Kong 6
PL - Polonia 6
EU - Europa 5
DK - Danimarca 4
IR - Iran 4
NZ - Nuova Zelanda 4
RU - Federazione Russa 4
CL - Cile 3
HU - Ungheria 3
IQ - Iraq 3
PK - Pakistan 3
RO - Romania 3
AE - Emirati Arabi Uniti 2
AU - Australia 2
BD - Bangladesh 2
CH - Svizzera 2
MK - Macedonia 2
AL - Albania 1
AR - Argentina 1
BG - Bulgaria 1
EG - Egitto 1
IL - Israele 1
IM - Isola di Man 1
JO - Giordania 1
KH - Cambogia 1
LT - Lituania 1
MC - Monaco 1
MD - Moldavia 1
PE - Perù 1
PH - Filippine 1
RS - Serbia 1
Totale 17.150
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Città #
Dublin 2.058
Chandler 1.439
Jacksonville 1.436
Santa Clara 1.128
Beijing 366
Singapore 327
Ashburn 280
Boardman 280
Princeton 280
Dearborn 263
Medford 249
Bremen 219
Ann Arbor 205
Wilmington 193
Hefei 168
San Mateo 162
Woodbridge 158
Nanjing 154
Roxbury 153
Naples 148
Caserta 134
Kunming 120
New York 107
Jinan 92
Cava 70
Cambridge 66
Guangzhou 55
Des Moines 51
Düsseldorf 50
Munich 50
Nanchang 50
Napoli 48
Hebei 43
Mugnano di Napoli 42
Aversa 40
Houston 40
Shenyang 40
Brussels 39
Zhengzhou 38
Redwood City 35
Auburn Hills 31
Norwalk 31
Helsinki 30
Istanbul 29
Mountain View 29
Rome 29
Seoul 29
Brno 27
Dong Ket 26
Los Angeles 23
Ningbo 23
Venice 21
Hangzhou 19
Milan 19
Shaoxing 17
Lanzhou 15
Shanghai 15
Changsha 14
Fuzhou 14
Baotou 13
Chengdu 13
Hanover 13
Chongqing 12
Fairfield 12
Xian 12
Tianjin 11
Wuhan 11
Afragola 10
Taizhou 10
Arzano 9
Grafing 9
Haikou 9
Paris 9
Florence 8
Chaoyang 7
Falls Church 7
Lappeenranta 7
Nocera Inferiore 7
Santa Maria Capua Vetere 7
Taipei 7
Tappahannock 7
Wenzhou 7
Aiello del Sabato 6
Jinhua 6
London 6
Nanning 6
Quzhou 6
Siena 6
Battipaglia 5
Brusciano 5
Campinas 5
Guiyang 5
Huzhou 5
Izmir 5
L'aquila 5
Mcallen 5
Modena 5
Pioltello 5
Seattle 5
Shenzhen 5
Totale 11.630
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Nome #
"2-FENIL-IMIDAZO[1,2-B]PIRIDAZINE AD ATTIVITA' ANALGESICA ED ANTIEPILETTICA" 148
Cannabinoid receptor 2 as anti-obesity target: inflammation, fat storage and browning modulation. 140
SOSTITUZIONE BIOISOSTERICA DEL GRUPPO AMMIDICO DI 4-CHINOLON-3-CARBOSSAMIDI6-SOSTITUITE:LIGANDI CB2 POTENTI E SELETTIVI PROVVISTI DI MIGLIOR PROFILO CHIMICO-FISICO . 135
Cannabinoid receptor 2-63 QQ varianti s associated with severe necroinflammation in chronic epatiti C 117
COCAINE USE AND EFFECTS Scientific and statistical dossier 115
PC1, a non-peptide PKR1-preferring antagonist, reduces pain behavior and spinal neuronal sensitization in neuropathic mice. 111
D-Aspartate drinking solution alleviates pain and cognitive impairment in neuropathic mice. 110
USO DEI BISFOSFONATI PER LA PREPARAZIONE DI FORMULAZIONI FARMACEUTICHE PER IL TRATTAMENTO DEI SINTOMI ASSOCIATI A DOLORE NEUROPATICO 109
Association between cannabinoid receptor type 2 Q63R variant and oligo/polyarticular juvenile idiopathic arthritis 105
MMPIP, an mGluR7-selective negative allosteric modulator, alleviates pain and normalizes affective and cognitive behavior in neuropathic mice 104
Palmitoylethanolamide reduces pain-related behaviors and restores glutamatergic synapses homeostasis in the medial prefrontal cortex of neuropathic mice 103
1-(2′,4′-dichlorophenyl)-6-methyl-N-cyclohexylamine-1,4-dihy droindeno[1,2-c]pyrazole-3-carboxamide, a novel CB2 agonist, alleviates neuropathic pain through functional microglial changes in mice 99
Chalcone derivatives activate and desensitize the transient receptor potential ankyrin 1 cation channel, subfamily A, member 1 TRPA1 ion channel: structure-activity relationships in vitro and anti-nociceptive and anti-inflammatory activity in vivo 97
Ultrapotent effects of salvinorin A, a hallucinogenic compound from Salvia divinorum, on LPS-stimulated murine macrophages and its anti-inflammatory action in vivo. 96
1-(2',4'-dichlorophenyl)-6-methyl-N-cyclohexylamine-1,4-dihydroindeno[1,2-c]pyrazole-3-carboxamide, a novel CB2 agonist, alleviates neuropathic pain through functional microglial changes in mice. Neurobiol Dis. 2010 Jan;37(1):177-85. Epub 2009 Oct 3. PubMed PMID: 19804829 95
La patologia dolorosa cronica e il problema della ‘oppiofobia’ 93
Endocannabinoid Research Group (ERG), Italy. The endovanilloid/endocannabinoid system: a new potential target for osteoporosis therapy. 92
Cannabinoid receptor 2 Q63R variant could modulate the relationship between childhood obesity and age at menarche 91
Profarmaco galattosilato della n-omega-nitro-l-arginina (nagal) ad uso analgesico ed antinfiammatorio con migliori caratteristiche farmacocinetiche e di tollerabilità del farmaco di partenza 90
Neuroimmune-driven neuropathic pain establishment: A focus on gender differences 89
Dorsal striatum metabotropic glutamate receptor 8 affects nocifensive responses and rostral ventromedial medulla cell activity in neuropathic pain conditions. 88
The antinociceptive effect of tramadol in the formalin test is mediated by the serotonergic component 87
The antinociceptive effect of 2-chloro-2'-C-methyl-N6-cyclopentyladenosine (2'-Me-CCPA), a highly selective adenosine A1 receptor agonist, in the rat 85
Age-Related Changes in D-Aspartate Oxidase Promoter Methylation Control Extracellular D-Aspartate Levels and Prevent Precocious Cell Death during Brain Aging 85
EP1 receptor within the ventrolateral periaqueductal grey controls thermonociception and rostral ventromedial medulla cell activity in healthy and neuropathic rat 84
Association Between a Polymorphism in Cannabinoid Receptor 2 and Severe Necroinflammation in Patients With Chronic Hepatitis C. 83
Palmitoylethanolamide induces microglia changes associated with increased migration and phagocytic activity: Involvement of the CB2 receptor 83
Palmitoylethanolamide reduces neuropsychiatric behaviors by restoring cortical electrophysiological activity in a mouse model of mild traumatic brain injury 83
Cannabinoid receptor type 2 functional variant influences liver damage in children with non-alcoholic fatty liver disease 82
Salvinorin A reduces mechanical allodynia and spinal neuronal hyperexcitability induced by peripheral formalin injection. 81
Changes in cannabinoid receptor subtype 1 activity and interaction with metabotropic glutamate subtype 5 receptors in the periaqueductal gray-rostral ventromedial medulla pathway in a rodent neuropathic pain model. 80
Changes in spinal and supraspinal endocannabinoid levels in neuropathic rats 80
Blockade of glutamate mGlu5 receptors in a rat model of neuropathic pain prevents early over-expression of pro-apoptotic genes and morphological changes in dorsal horn lamina II 79
Design and Synthesis of New Transient Receptor Potential Vanilloid Type-1 (TRPV1) Channel Modulators: Identification, Molecular Modeling Analysis, and Pharmacological Characterization of the N-(4-Hydroxy-3-methoxybenzyl)-4-(thiophen-2-yl)butanamide, a Small Molecule Endowed with Agonist TRPV1 Activity and Protective Effects against Oxidative Stress. 79
Metabotropic glutamate receptor subtype 7 in the dorsal striatum oppositely modulates pain in sham and neuropathic rats 79
Involvement of subtype 1 metabotropic glutamate receptors in apoptosis and caspase-7 over-expression in spinal cord of neuropathic rats 78
Interaction between vanilloid and glutamate receptors in the central modulation of nociception 78
Differential roles of mGlu8 receptors in the regulation of glutamate and gamma-aminobutyric acid release at periaqueductal grey level. Neuropharmacology 78
The cannabinoid receptor type 2 as mediator of mesenchymal stromal cell immunosuppressive properties. 78
Stealth liposomes encapsulating zoledronic acid: a new opportunity to treat neuropathic pain. 78
5'-Chloro-5'-deoxy-(±)-ENBA, a potent and selective adenosine A(1) receptor agonist, alleviates neuropathic pain in mice through functional glial and microglial changes without affecting motor or cardiovascular functions. Molecules. 78
Exposure to allergen causes changes in nts neural activities after intratracheal capsaicin application, in endocannabinoid levels and in the glia morphology of nts 78
The blockade of the transient receptor potential vanilloid type 1 and fatty acid amide hydrolase decreases symptoms and central sequelae in the medial prefrontal cortex of neuropathic rats. 77
Selective melatonin MT2 receptor ligands relieve neuropathic pain through modulation of brainstem descending antinociceptive pathways 76
The 17-β-oestradiol inhibits osteoclast activity by increasing the cannabinoid CB2 receptor expression. 75
Development and Pharmacological Characterization of Selective Blockers of 2-Arachidonoyl Glycerol Degradation with Efficacy in Rodent Models of Multiple Sclerosis and Pain 75
Effects of intra-ventrolateral periaqueductal grey palmitoylethanolamide on thermoceptive threshold and rostral ventromedial medulla cell activity 74
Effects of (S)-3,4-DCPG, an mGlu8 receptor agonist, on inflammatory and neuropathic pain in mice 74
Differential roles of mGlu8 receptors in the regulation of glutamate and gamma-aminobutyric acid release at periaqueductal grey level 74
N-acyl-N'-methyl-N-(1,3,3-trimethylbicyclo[2.2.1]hept-2-yl) benzamidines with hypotensive activity 74
Structural insight into the optimization of ethyl 5-hydroxybenzo[g] indol-3-carboxylates and their bioisosteric analogues as 5-LO/mPGES-1 dual inhibitors able to suppress inflammation 74
Intraperiaqueductal gray glycine and D-serine exert dual effects on rostral ventromedial medulla ON- and OFF-cell activity and thermoceptive threshold in the rat 73
The impact of the CB2-63 polymorphism on the histological presentation of chronic hepatitis B. 73
D-aspartate modulates nociceptive-specific neuron activity and pain threshold in inflammatory and neuropathic pain condition in mice 73
Characterisation of mGluRs which modulate nociception in the PAG of the mouse 73
CNR2 functional variant (Q63R) influences childhood immune thrombocytopenic purpura. 73
Cannabinoid receptor 2-63 QQ variant is associated with persistently normal aminotransferase serum levels in chronic hepatitis C 72
Analgesic actions of N-arachidonoyl-serotonin, a fatty acid amide hydrolase inhibitor with antagonistic activity at vanilloid TRPV1 receptors 72
PKCβII-mediated cross-talk of TRPV1/CB2 modulates the glucocorticoid-induced osteoclast overactivity 72
The A1 adenosine receptor as a new player in microglia physiology 71
Elevation of endocannabinoid levels in the ventrolateral periaqueductal grey through inhibition of fatty acid amide hydrolase affects descending nociceptive pathways via both CB1 and TRPV1 receptors. J Pharmacol Exp The 71
Characterization of mGluRs which modulate nociception in the PAG of the mouse 71
A single subcutaneous injection of ozone prevents allodynia and decreases the over-expression of pro-inflammatory caspases in the orbito-frontal cortex of neuropathic mice 71
The cannabinoid receptor type 2 Q63R variant increases the risk of celiac disease: implication for a novel molecular biomarker and future therapeutic intervention. 71
The genetic ablation or pharmacological inhibition of TRPV1 signalling is beneficial for the restoration of quiescent osteoclast activity in ovariectomized mice. 70
Intra-periaqueductal grey microinjections of an imidazo[1,2-b]pyridazine derivative, DM2, affects rostral ventromedial medulla cell activity and shows antinociceptive effect 70
Evidence of muscarinic receptor subtypes in airway smooth muscle of normal volunteers and of chronic obstructive pulmonary disease patients 70
2-pentadecyl-2-oxazoline prevents cognitive and social behaviour impairments in the Amyloid β-induced Alzheimer-like mice model: Bring the α2 adrenergic receptor back into play 69
Excitatory amino acids and cardiovascular apparatus: experimental studies on conscious rats with L-glutamate, N-methyl-D-aspartate, kainate and quisqualate 69
Role of reactive oxygen species and spinal cord apoptotic genes in the development of neuropathic pain 69
Effects of persistent nociception on periaqueductal gray glycine release 69
Effect of Prolonged Moderate Exercise on the Changes of Nonneuronal Cells in Early Myocardial Infarction. 69
Palvanil, a non-pungent capsaicin analogue, inhibits inflammatory and neuropathic pain with little effects on bronchopulmonary function and body temperature. 69
Metabotropic glutamate receptor 7: From synaptic function to therapeutic implications 69
Effects of a metabotropic glutamate receptor subtype 7 negative allosteric modulator in the periaqueductal grey on pain responses and rostral ventromedial medulla cell activity in rat 68
In vitro and in vivo pharmacology of synthetic olivetol- or resorcinol-derived cannabinoid receptor ligands 68
N-methyl-d-aspartate receptors modulate extracellular dopamine concentration and metabolism in rat hippocampus and striatum in vivo 68
Basic and Pharmacological Aspects of Cannabinoid Activity in Nervous and Reproductive Systems 68
Antineuropathic profile of N-palmitoylethanolamine in a rat model of oxaliplatin-induced neurotoxicity 68
Contribution of sensory nerves to LPS-induced hyperresponsiveness of human isolated bronchi. 67
Hypothalamic paraventricular nucleus involvement in the pressor response to N-methyl-d-aspartic acid in the periaqueductal grey matter 67
Role of metabotropic glutamate receptor 1 in the basolateral amygdala-driven prefrontal cortical deactivation in inflammatory pain in the rat 67
Cannabinoid Receptor Type 2, but not Type 1, is Up-Regulated in Peripheral Blood Mononuclear Cells of Children Affected by Autistic Disorders. 67
The plant cannabinoid D9-tetrahydrocannabivarin can decrease signs of inflammation and inflammatory pain in mice 67
The 17-estradiol inhibits osteoclast activity by increasing the cannabinoid CB2 receptor expression 67
d-Aspartic acid ameliorates painful and neuropsychiatric changes and reduces β-amyloid Aβ1-42 peptide in a long lasting model of neuropathic pain. 67
Olanzapine, but not clozapine, increases glutamate release in the prefrontal cortex of freely moving mice by inhibiting D-aspartate oxidase activity. 67
Supraspinal metabotropic glutamate receptor subtype 8: a switch to turn off pain. 66
The endovanilloid/endocannabinoid system: A new potential target for osteoporosis therapy 66
Intra-Periaqueductal Gray glycine and D-serine exert dual effects on the Rostral Ventromedial Medulla ON and OFF cell activity and thermal threshold in the rat 66
Prenatal and postnatal vanadium exposure in rats: effect on vasomotor reactivity development of pups 66
Investigations on the 4-quinolone-3-carboxylic acid motif part 5: modulation of the physicochemical profile of a set of potent and selective cannabinoid-2 receptor ligands through a bioisosteric approach 66
Gliosis alters expression and uptake of spinal glial amino acid transporters in a mouse neuropathic pain model 66
CB2 and TRPV1 receptors oppositely modulate in vitro human osteoblast activity 66
Altered gut microbiota and endocannabinoid system tone in vitamin D deficiency-mediated chronic pain. 66
Palmitoylethanolamide reduces formalin-induced neuropathic-like behaviour through spinal glial/microglial phenotypical changes in mice 65
New N-arachidonoylserotonin analogues with potential "dual" mechanism of action against pain 64
Modification of cysteinyl leukotriene receptors expression in capsular contracture: follow-up study and definitive results 64
Iron overload causes osteoporosis in Thalassemia Major patients through interaction with TRPV1 channels. 64
Effects of imipramine on raphe nuclei and prefrontal cortex extracellular serotonin levels in the rat 64
Totale 7.950
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Categoria #
all - tutte 68.741
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 68.741
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20202.056 0 0 0 0 0 285 994 453 185 55 69 15
2020/20212.255 205 23 267 109 377 31 365 239 25 288 236 90
2021/20221.928 185 27 17 36 619 30 41 42 74 193 149 515
2022/20234.863 319 78 69 554 614 460 20 365 2.162 47 83 92
2023/20241.769 166 75 68 152 500 146 26 277 11 11 76 261
2024/20251.870 39 50 187 240 729 625 0 0 0 0 0 0
Totale 17.751