IRIS
SPINA, Annamaria
 Distribuzione geografica
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Continente #
EU - Europa 6.034
NA - Nord America 3.277
AS - Asia 2.217
SA - Sud America 289
AF - Africa 25
OC - Oceania 4
Continente sconosciuto - Info sul continente non disponibili 2
Totale 11.848
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Nazione #
RU - Federazione Russa 3.472
US - Stati Uniti d'America 3.221
SG - Singapore 811
IE - Irlanda 719
IT - Italia 538
CN - Cina 519
HK - Hong Kong 335
UA - Ucraina 326
GB - Regno Unito 293
DE - Germania 275
BR - Brasile 247
VN - Vietnam 199
FI - Finlandia 104
SE - Svezia 102
KR - Corea 96
IN - India 83
FR - Francia 68
TR - Turchia 57
GR - Grecia 55
BD - Bangladesh 43
CA - Canada 28
MX - Messico 23
BE - Belgio 20
JP - Giappone 20
AR - Argentina 17
NL - Olanda 15
AT - Austria 11
IQ - Iraq 9
ZA - Sudafrica 9
PL - Polonia 8
EC - Ecuador 7
ID - Indonesia 7
CL - Cile 5
ES - Italia 5
IR - Iran 5
MA - Marocco 5
PK - Pakistan 5
BG - Bulgaria 4
NO - Norvegia 4
RO - Romania 4
VE - Venezuela 4
AU - Australia 3
BO - Bolivia 3
HU - Ungheria 3
JO - Giordania 3
KZ - Kazakistan 3
PH - Filippine 3
PT - Portogallo 3
TH - Thailandia 3
UY - Uruguay 3
UZ - Uzbekistan 3
AE - Emirati Arabi Uniti 2
CH - Svizzera 2
CO - Colombia 2
EG - Egitto 2
EU - Europa 2
LT - Lituania 2
NP - Nepal 2
TN - Tunisia 2
AM - Armenia 1
AO - Angola 1
AZ - Azerbaigian 1
BS - Bahamas 1
CR - Costa Rica 1
CY - Cipro 1
CZ - Repubblica Ceca 1
DO - Repubblica Dominicana 1
DZ - Algeria 1
ET - Etiopia 1
GA - Gabon 1
IL - Israele 1
KE - Kenya 1
KG - Kirghizistan 1
KH - Cambogia 1
KY - Cayman, isole 1
MU - Mauritius 1
NZ - Nuova Zelanda 1
OM - Oman 1
PA - Panama 1
PY - Paraguay 1
SA - Arabia Saudita 1
SN - Senegal 1
TW - Taiwan 1
Totale 11.848
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Città #
Moscow 1.162
Dublin 716
Jacksonville 492
Chandler 465
Singapore 382
Santa Clara 375
Hong Kong 331
San Jose 283
Caserta 259
Ashburn 123
Princeton 92
Seoul 89
Ann Arbor 85
Beijing 83
Medford 75
Bremen 70
Boardman 63
Ho Chi Minh City 60
Hanoi 56
New York 51
San Mateo 51
Wilmington 50
Bengaluru 48
Roxbury 46
Woodbridge 39
Hefei 38
Munich 32
Dallas 30
Naples 30
Cambridge 29
The Dalles 24
Los Angeles 21
Nanjing 20
Orem 20
Brussels 19
Düsseldorf 19
Mountain View 18
Napoli 18
Des Moines 17
Rome 17
Houston 16
Da Nang 14
São Paulo 14
Frankfurt am Main 13
Jinan 13
Milan 13
Turku 12
Helsinki 11
Auburn Hills 10
Zhengzhou 10
Tianjin 9
Belo Horizonte 8
Haiphong 8
Memphis 8
Mexico 8
Toronto 8
Atlanta 7
Boston 7
Giugliano In Campania 7
Mexico City 7
Nuremberg 7
Brooklyn 6
Changsha 6
Chennai 6
Chicago 6
Dong Ket 6
Guangzhou 6
Hangzhou 6
Johannesburg 6
Mirabella Eclano 6
Ottawa 6
San Francisco 6
Warsaw 6
Amsterdam 5
Jakarta 5
London 5
Manchester 5
Mumbai 5
New Delhi 5
Norwalk 5
Orta di Atella 5
Rio de Janeiro 5
Venice 5
Vienna 5
Wuhan 5
Aversa 4
Bologna 4
Campinas 4
Columbus 4
Curitiba 4
Fortaleza 4
Hanover 4
Hyderabad 4
Lanzhou 4
Ningbo 4
Oslo 4
Phoenix 4
Piscataway 4
Porto Alegre 4
Redwood City 4
Totale 6.300
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Nome #
Histone deacetylase inhibitors increase p27Kip1 by affecting its ubiquitin-dependent degradation through Skp2 down-regulation 256
Lactic dehydrogenase and cancer: an overview 218
Adiponectin down-regulates CREB and inhibits proliferation of A549 lung cancer cells 212
cAMP elevation down-regulates beta3 integrin and Focal Adhesion Kinase and inhibits leptin-induced migration of MDA-MB-231 breast cancer cells 198
Forskolin potentiates the effects of GSKJ4 in human acute myeloid leukemia cells through Protein Kinase A pathway 195
Adenylate cyclase/cAMP pathway downmodulation counteracts apoptosis induced by IFN-alpha in human epidermoid cancer cells. 189
S-Adenosylmethionine Affects ERK1/2 and STAT3 Pathways and Induces Apoptosis in Osteosarcoma Cells. 187
Chlorogenic acid activates ERK1/2 and inhibits proliferation of osteosarcoma cells 187
The Natural cAMP Elevating Compound Forskolin in Cancer Therapy: Is it Time? 184
A novel G-protein active on signal transduction 183
5-Fluorouracil induces apoptosis in rat cardiocytes through intracellular oxidative stress. 183
Change in TNF-alpha receptor expression is a relevant event in doxorubicin-induced H9c2 cardiomyocyte cell death 179
Adenylate Cyclase modulation by proteasome mediated αs accumulation in mammalian cells 173
Forskolin improves sensitivity to doxorubicin of triple negative breast cancer cells via Protein Kinase A-mediated ERK1/2 inhibition 170
A stimulating effect of guanyl nucleotides on the rat-liver soluble cyclic GMP high-affinity phosphodiesterase activity 169
Adenylate cyclase regulation via proteasome-mediated modulation of Galphas levels. 165
Inorganic Phosphate Prevents Erk1/2 and Stat3 Activation and Improves Sensitivity to Doxorubicin of MDA-MB-231 Breast Cancer Cells 163
cAMP pathway in differentiating myoblast 162
An in vitro model for dissecting distraction osteogenesis 161
Chlorogenic acid enhances doxorubicin-mediated cytotoxic effect in osteosarcoma cells 161
Cellular response to PCL/ZrO2hybrid materials synthesized via sol-gel as a function of PCL content 160
Doxorubicin (DXR) treatment stimulates TNF-α expression in the rat cardiomyoblast cell line (H9c2), triggering mechanisms of auto-toxicity 158
Gli effetti della fosforilazione di proteine di membrana, PKC mediata, sull’attività adenilato ciclasica di piastrine umane 155
AdipoRon Affects Cell Cycle Progression and Inhibits Proliferation in Human Osteosarcoma Cells 153
Differentiation of H9c2 cardiomyoblasts: The role of adenylate cyclase system. 152
Forskolin affects proliferation, migration and Paclitaxel-mediated cytotoxicity in non-small-cell lung cancer cell lines via adenylyl cyclase/cAMP axis 150
Adenylate Cyclase activity in rat thyroid epithelial cells (PC-Cl3) treated in vivo with lovastatin 150
Adenylate cyclase and cell cycle 148
Cholera toxin-mediated ADP-ribosylation " in vivo ": A useful tool for studying the G-protein cycle. 144
G-Protein modulation of the adenylate cyclase (AC) activity in control and Ras-virus transformed epithelial cells. 144
Targeting protein kinase A in cancer therapy: an update. 141
Forskolin sensitizes pancreatic cancer cells to gemcitabine via Stat3 and Erk1/2 inhibition 141
AdipoRon and Pancreatic Ductal Adenocarcinoma: a future perspective in overcoming chemotherapy-induced resistance? 138
INHIBITION OF ONCOGENIC EFFECTS OF LEPTIN BY CAMP ELEVATION IN TRIPLE NEGATIVE BREAST CANCER CELLS 131
Anoxia-inducible endonuclease activity as a potential basis of the genomic instability of cancer cells 130
Ubiquitin/proteasome system and adenylate cyclase: their functional interrelations 130
Targeting p27Kip1 protein: its relevance in the therapy of human cancer. 128
The influence of the polymer amount on the biological properties of PCL/ZrO2hybrid materials synthesized via sol-gel technique 128
Leptin enhances growth inhibition by cAMP elevating agents through apoptosis of MDA-MB-231 breast cancer cells 126
Increased adenylate cyclase activity in rat thyroid epithelial cells expressing viral ras genes 126
Inorganic phosphate enhances sensitivity of human osteosarcoma U2OS cells to doxorubicin via a p53-dependent pathway. 125
Integrating Gemcitabine-Based Therapy With AdipoRon Enhances Growth Inhibition in Human PDAC Cell Lines 125
Treatment of v-Ki-ras-transformed SVC1 cells with low retinoic acid induces malignancy reversion associated with ras p21 down-regulation 123
Adriamycin causes hyperlipemia as a consequence of nephrotoxicity 122
Inorganic Phosphate as A Signaling Molecule: A Potential Strategy in Osteosarcoma Treatment 122
Inorganic phosphate as a new signalling molecule: effects on the adenylate cyclase/cAMP system 121
Synergistic cytotoxic effects of inorganic phosphate and chemotherapeutic drugs on human osteosarcoma cells. 121
Inorganic phosphate inhibits growth of human osteosarcoma U2OS cells via adenylate cyclase/cAMP pathway 119
The phosphorylation degree of the proteins in the neoplastic epidermoid A431 cells is also affected by a Ca2+-calmodulin dependent modulation. 119
Retinoic acid modulates external signal metabolic pathways in SVCI and KiSVC1 epithelial cells. 119
TNF-alpha receptors expression level changes are a relevant event in Doxorubicin-induced H9c2 cardiomyocytes apoptosis 119
Pleiotropic biochemical effects of retinoic acid: are they functionally correlated? 119
Valutazioni di metodiche di criopreservazione di piastrine umane sulla base di parametri fisici, biochimici e funzionali 118
Forskolin sensitizes human acute myeloid leukemia cells to H3K27me2/3 demethylases GSKJ4 inhibitor via Protein Kinase A 118
Inorganic phosphate as a novel signalling molecule with antiproliferative action in MDA-MB-231 breast cancer cells 116
Tissue Transglutaminase and adenylate cyclase interactions in balb-C 3T3 fibroblast membranes 115
INORGANIC PHOSPHATE AS A NOVEL SIGNALING MOLECULE: ITS POTENTIAL USE IN THE OSTEOSARCOMA THERAPY 113
Meccanismi di regolazione delle attività fosfodiesterasiche in fegato di ratto 113
Regulatory mechanism of the soluble phosphodiesterase activities in rat liver. 112
Leptin affects adenylate cyclase activity in H9c2 cardiac cell line: effects of short- and long-term exsposure 112
LEPTIN POTENTIATES ANTIPROLIFERATIVE ACTION OF cAPM ELEVATION VIA PROTEIN KINASE A DOWN-REGULATION IN BREAST CANCER CELLS. 112
Low insulin concentrations stimulate in vitro the soluble guanylate cyclase activity of rat liver. 112
Functional implications of human tissue transglutaminase in the modulation of signal transduction via G-proteins 111
Protein Kinase A as a biological target in cancer therapy. 111
GTPase activity of Transglutaminase secreted from rat coagulation gland 111
Integrating leptin and cAMP signalling pathways in triple-negative breast cancer cells. 111
Leptin effect on adenylate cyclase/cAMP pathway in rat H9c2 myoblasts 109
Protein kinase activities in epidermoid cells (A431) 108
The effects of membrane protein phosphorilation on the bound adenylate cyclase activity in crude preparation of brain membranes 108
Novel molecular mechanisms by inorganic phosphate in osteosarcoma U2OS cells 107
Role of calcium in chloride secretion mediated by cAMP pathway activation in rabbit distal colon mucosa 106
ras oncogene-induced transformation of a rat seminal vesicle epithelial cell line produces a marked increase of adenylate cyclase and protein kinase C activities. 106
Protein kinase a detection in human urine samples 105
tTGase/G alpha h protein expression inhibits adenylate cyclase activity in Balb-C 3T3 fibroblasts membranes 104
Early effects by retinoic acid (RA) at the membrane level in eucaryotic cells. 103
Protein kinase C activities are increased in rat thyroid epithelial cells expressing V-ras genes 102
Relationships between doxorubicin (Doxo)-induced damage and TNF-α pathways in H9c2 cardiomyoblast 101
Effect of vitamin C on pre-osteoblast gene expression 101
Interaction between f- and cholera toxin " in vivo " ADP-ribosilation on the adenylate cyclase acyivity modulation. 99
Leptin effects on rat cardiomyocytes: a possible involvement of cAMP signal transduction pathway in heart failure development 99
Role of extracellular Ca++ in PGE2 mediated chloride secretion across rabbit distal colon mucosa 98
GTP-binding proteins and protein kinase C activities (PK). 96
The effects of polyamines on the cyclic AMP efflux and metabolism in E. coli B cells 95
The KDM inhibitor GSKJ4 triggers CREB down-regulation via a protein kinase A and proteasome dependent mechanism in human acute myeloid leukemia cells 94
Targeting CREB in Cancer Therapy: A Key Candidate or One of Many? An Update 94
Histidine degradation enzymes in rat liver: induction by high protein intake 93
The effect on adenylate cyclase (AC) system of in vivo treatment with inorganic phosphate on osteoblasts during differentiation 90
GTPase and transglutaminase are associated in the secretion of the rat anterior prostate 89
Steroid receptors in epithelial ovarian carcinoma: relation to clinical parameters and survival 88
In vivo treatment by retinoic aci (RA) triggers early interaction among protein kinase activity in ras-virus transformed cells 88
Effect of carnitine on heart alterations caused by tricyclic antidepressants 86
In vitro phosphorylation of high molecular weight glutenin subunits from wheat endosperm 83
Phosphorylation of Wheat Gluteinin Subunits 78
Protein kinase C and G proteins 75
Totale 12.272
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Categoria #
all - tutte 39.598
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 39.598
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/202125 0 0 0 0 0 0 0 0 0 0 0 25
2021/2022669 54 3 10 20 217 9 6 33 25 54 64 174
2022/20231.562 108 58 16 166 171 136 2 89 719 27 31 39
2023/2024442 57 17 19 40 138 36 7 13 7 3 45 60
2024/20251.334 3 4 21 35 247 222 239 111 170 128 94 60
2025/20265.716 256 185 292 259 441 3.283 292 237 177 132 77 85
Totale 12.272