SPINA, Annamaria
 Distribuzione geografica
Continente #
EU - Europa 6.046
NA - Nord America 3.371
AS - Asia 2.248
Continente sconosciuto - Info sul continente non disponibili 426
SA - Sud America 293
AF - Africa 25
OC - Oceania 4
Totale 12.413
Nazione #
RU - Federazione Russa 3.472
US - Stati Uniti d'America 3.308
SG - Singapore 834
IE - Irlanda 719
IT - Italia 544
CN - Cina 523
HK - Hong Kong 339
UA - Ucraina 326
GB - Regno Unito 293
DE - Germania 276
BR - Brasile 251
VN - Vietnam 199
FI - Finlandia 104
SE - Svezia 102
KR - Corea 96
IN - India 83
FR - Francia 68
TR - Turchia 57
GR - Grecia 55
BD - Bangladesh 43
CA - Canada 31
MX - Messico 24
BE - Belgio 20
JP - Giappone 20
AR - Argentina 17
NL - Olanda 16
AT - Austria 11
ES - Italia 9
IQ - Iraq 9
ZA - Sudafrica 9
PL - Polonia 8
EC - Ecuador 7
ID - Indonesia 7
CL - Cile 5
IR - Iran 5
MA - Marocco 5
PK - Pakistan 5
BG - Bulgaria 4
NO - Norvegia 4
RO - Romania 4
VE - Venezuela 4
AU - Australia 3
BO - Bolivia 3
HU - Ungheria 3
JO - Giordania 3
KZ - Kazakistan 3
PH - Filippine 3
PT - Portogallo 3
TH - Thailandia 3
UY - Uruguay 3
UZ - Uzbekistan 3
AE - Emirati Arabi Uniti 2
CH - Svizzera 2
CO - Colombia 2
EG - Egitto 2
EU - Europa 2
LT - Lituania 2
NP - Nepal 2
TN - Tunisia 2
AM - Armenia 1
AO - Angola 1
AZ - Azerbaigian 1
BS - Bahamas 1
CR - Costa Rica 1
CY - Cipro 1
CZ - Repubblica Ceca 1
DO - Repubblica Dominicana 1
DZ - Algeria 1
ET - Etiopia 1
GA - Gabon 1
HN - Honduras 1
IL - Israele 1
KE - Kenya 1
KG - Kirghizistan 1
KH - Cambogia 1
KY - Cayman, isole 1
MU - Mauritius 1
NZ - Nuova Zelanda 1
OM - Oman 1
PA - Panama 1
PY - Paraguay 1
SA - Arabia Saudita 1
SN - Senegal 1
SV - El Salvador 1
TT - Trinidad e Tobago 1
TW - Taiwan 1
Totale 11.989
Città #
Moscow 1.162
Dublin 716
Jacksonville 492
Chandler 465
Santa Clara 390
Singapore 384
Hong Kong 333
San Jose 283
Caserta 259
Ashburn 145
Princeton 92
Seoul 89
Ann Arbor 85
Beijing 85
Medford 75
Bremen 70
Boardman 64
Ho Chi Minh City 60
Hanoi 56
New York 52
San Mateo 51
Wilmington 50
Bengaluru 48
Roxbury 46
Woodbridge 39
Hefei 38
Dallas 32
Munich 32
Naples 30
Cambridge 29
The Dalles 25
Los Angeles 21
Nanjing 20
Orem 20
Brussels 19
Düsseldorf 19
Houston 18
Mountain View 18
Napoli 18
Des Moines 17
Rome 17
São Paulo 16
Milan 15
Da Nang 14
Frankfurt am Main 14
Jinan 13
Turku 12
Helsinki 11
Auburn Hills 10
Zhengzhou 10
Council Bluffs 9
Tianjin 9
Atlanta 8
Belo Horizonte 8
Haiphong 8
Memphis 8
Mexico 8
Mexico City 8
Toronto 8
Boston 7
Giugliano In Campania 7
Nuremberg 7
Brooklyn 6
Changsha 6
Chennai 6
Chicago 6
Dong Ket 6
Guangzhou 6
Hangzhou 6
Johannesburg 6
Mirabella Eclano 6
Ottawa 6
San Francisco 6
Warsaw 6
Afragola 5
Amsterdam 5
Jakarta 5
London 5
Manchester 5
Mumbai 5
New Delhi 5
Norwalk 5
Orta di Atella 5
Phoenix 5
Rio de Janeiro 5
Seattle 5
Venice 5
Vienna 5
Wuhan 5
Aversa 4
Bologna 4
Campinas 4
Columbus 4
Curitiba 4
Fortaleza 4
Hanover 4
Hyderabad 4
Lanzhou 4
Montreal 4
Ningbo 4
Totale 6.365
Nome #
Histone deacetylase inhibitors increase p27Kip1 by affecting its ubiquitin-dependent degradation through Skp2 down-regulation 257
Lactic dehydrogenase and cancer: an overview 219
Adiponectin down-regulates CREB and inhibits proliferation of A549 lung cancer cells 213
cAMP elevation down-regulates beta3 integrin and Focal Adhesion Kinase and inhibits leptin-induced migration of MDA-MB-231 breast cancer cells 201
Forskolin potentiates the effects of GSKJ4 in human acute myeloid leukemia cells through Protein Kinase A pathway 200
Adenylate cyclase/cAMP pathway downmodulation counteracts apoptosis induced by IFN-alpha in human epidermoid cancer cells. 193
Chlorogenic acid activates ERK1/2 and inhibits proliferation of osteosarcoma cells 191
The Natural cAMP Elevating Compound Forskolin in Cancer Therapy: Is it Time? 189
S-Adenosylmethionine Affects ERK1/2 and STAT3 Pathways and Induces Apoptosis in Osteosarcoma Cells. 187
A novel G-protein active on signal transduction 187
5-Fluorouracil induces apoptosis in rat cardiocytes through intracellular oxidative stress. 185
Change in TNF-alpha receptor expression is a relevant event in doxorubicin-induced H9c2 cardiomyocyte cell death 180
Adenylate Cyclase modulation by proteasome mediated αs accumulation in mammalian cells 175
Forskolin improves sensitivity to doxorubicin of triple negative breast cancer cells via Protein Kinase A-mediated ERK1/2 inhibition 171
A stimulating effect of guanyl nucleotides on the rat-liver soluble cyclic GMP high-affinity phosphodiesterase activity 170
Inorganic Phosphate Prevents Erk1/2 and Stat3 Activation and Improves Sensitivity to Doxorubicin of MDA-MB-231 Breast Cancer Cells 165
Adenylate cyclase regulation via proteasome-mediated modulation of Galphas levels. 165
cAMP pathway in differentiating myoblast 163
Chlorogenic acid enhances doxorubicin-mediated cytotoxic effect in osteosarcoma cells 163
Cellular response to PCL/ZrO2hybrid materials synthesized via sol-gel as a function of PCL content 162
An in vitro model for dissecting distraction osteogenesis 161
Doxorubicin (DXR) treatment stimulates TNF-α expression in the rat cardiomyoblast cell line (H9c2), triggering mechanisms of auto-toxicity 158
Gli effetti della fosforilazione di proteine di membrana, PKC mediata, sull’attività adenilato ciclasica di piastrine umane 156
AdipoRon Affects Cell Cycle Progression and Inhibits Proliferation in Human Osteosarcoma Cells 154
Differentiation of H9c2 cardiomyoblasts: The role of adenylate cyclase system. 153
Forskolin affects proliferation, migration and Paclitaxel-mediated cytotoxicity in non-small-cell lung cancer cell lines via adenylyl cyclase/cAMP axis 152
Adenylate Cyclase activity in rat thyroid epithelial cells (PC-Cl3) treated in vivo with lovastatin 151
Adenylate cyclase and cell cycle 149
Cholera toxin-mediated ADP-ribosylation " in vivo ": A useful tool for studying the G-protein cycle. 145
Targeting protein kinase A in cancer therapy: an update. 144
G-Protein modulation of the adenylate cyclase (AC) activity in control and Ras-virus transformed epithelial cells. 144
Forskolin sensitizes pancreatic cancer cells to gemcitabine via Stat3 and Erk1/2 inhibition 144
AdipoRon and Pancreatic Ductal Adenocarcinoma: a future perspective in overcoming chemotherapy-induced resistance? 139
INHIBITION OF ONCOGENIC EFFECTS OF LEPTIN BY CAMP ELEVATION IN TRIPLE NEGATIVE BREAST CANCER CELLS 134
Ubiquitin/proteasome system and adenylate cyclase: their functional interrelations 133
Anoxia-inducible endonuclease activity as a potential basis of the genomic instability of cancer cells 132
Targeting p27Kip1 protein: its relevance in the therapy of human cancer. 130
Leptin enhances growth inhibition by cAMP elevating agents through apoptosis of MDA-MB-231 breast cancer cells 128
The influence of the polymer amount on the biological properties of PCL/ZrO2hybrid materials synthesized via sol-gel technique 128
Integrating Gemcitabine-Based Therapy With AdipoRon Enhances Growth Inhibition in Human PDAC Cell Lines 127
Increased adenylate cyclase activity in rat thyroid epithelial cells expressing viral ras genes 126
Inorganic phosphate enhances sensitivity of human osteosarcoma U2OS cells to doxorubicin via a p53-dependent pathway. 125
Treatment of v-Ki-ras-transformed SVC1 cells with low retinoic acid induces malignancy reversion associated with ras p21 down-regulation 124
Adriamycin causes hyperlipemia as a consequence of nephrotoxicity 123
Forskolin sensitizes human acute myeloid leukemia cells to H3K27me2/3 demethylases GSKJ4 inhibitor via Protein Kinase A 123
Valutazioni di metodiche di criopreservazione di piastrine umane sulla base di parametri fisici, biochimici e funzionali 122
Inorganic Phosphate as A Signaling Molecule: A Potential Strategy in Osteosarcoma Treatment 122
Inorganic phosphate as a new signalling molecule: effects on the adenylate cyclase/cAMP system 121
The phosphorylation degree of the proteins in the neoplastic epidermoid A431 cells is also affected by a Ca2+-calmodulin dependent modulation. 121
Retinoic acid modulates external signal metabolic pathways in SVCI and KiSVC1 epithelial cells. 121
Pleiotropic biochemical effects of retinoic acid: are they functionally correlated? 121
Synergistic cytotoxic effects of inorganic phosphate and chemotherapeutic drugs on human osteosarcoma cells. 121
Inorganic phosphate inhibits growth of human osteosarcoma U2OS cells via adenylate cyclase/cAMP pathway 120
TNF-alpha receptors expression level changes are a relevant event in Doxorubicin-induced H9c2 cardiomyocytes apoptosis 119
Inorganic phosphate as a novel signalling molecule with antiproliferative action in MDA-MB-231 breast cancer cells 116
Tissue Transglutaminase and adenylate cyclase interactions in balb-C 3T3 fibroblast membranes 116
Low insulin concentrations stimulate in vitro the soluble guanylate cyclase activity of rat liver. 114
INORGANIC PHOSPHATE AS A NOVEL SIGNALING MOLECULE: ITS POTENTIAL USE IN THE OSTEOSARCOMA THERAPY 114
Meccanismi di regolazione delle attività fosfodiesterasiche in fegato di ratto 114
Protein Kinase A as a biological target in cancer therapy. 113
LEPTIN POTENTIATES ANTIPROLIFERATIVE ACTION OF cAPM ELEVATION VIA PROTEIN KINASE A DOWN-REGULATION IN BREAST CANCER CELLS. 113
Functional implications of human tissue transglutaminase in the modulation of signal transduction via G-proteins 112
Regulatory mechanism of the soluble phosphodiesterase activities in rat liver. 112
Leptin affects adenylate cyclase activity in H9c2 cardiac cell line: effects of short- and long-term exsposure 112
GTPase activity of Transglutaminase secreted from rat coagulation gland 112
Integrating leptin and cAMP signalling pathways in triple-negative breast cancer cells. 111
Leptin effect on adenylate cyclase/cAMP pathway in rat H9c2 myoblasts 110
The effects of membrane protein phosphorilation on the bound adenylate cyclase activity in crude preparation of brain membranes 109
Protein kinase activities in epidermoid cells (A431) 108
Role of calcium in chloride secretion mediated by cAMP pathway activation in rabbit distal colon mucosa 108
ras oncogene-induced transformation of a rat seminal vesicle epithelial cell line produces a marked increase of adenylate cyclase and protein kinase C activities. 108
Novel molecular mechanisms by inorganic phosphate in osteosarcoma U2OS cells 108
Protein kinase a detection in human urine samples 107
Early effects by retinoic acid (RA) at the membrane level in eucaryotic cells. 106
tTGase/G alpha h protein expression inhibits adenylate cyclase activity in Balb-C 3T3 fibroblasts membranes 105
Relationships between doxorubicin (Doxo)-induced damage and TNF-α pathways in H9c2 cardiomyoblast 103
Protein kinase C activities are increased in rat thyroid epithelial cells expressing V-ras genes 103
Effect of vitamin C on pre-osteoblast gene expression 102
Interaction between f- and cholera toxin " in vivo " ADP-ribosilation on the adenylate cyclase acyivity modulation. 101
Leptin effects on rat cardiomyocytes: a possible involvement of cAMP signal transduction pathway in heart failure development 100
Role of extracellular Ca++ in PGE2 mediated chloride secretion across rabbit distal colon mucosa 99
The effects of polyamines on the cyclic AMP efflux and metabolism in E. coli B cells 98
GTP-binding proteins and protein kinase C activities (PK). 97
The KDM inhibitor GSKJ4 triggers CREB down-regulation via a protein kinase A and proteasome dependent mechanism in human acute myeloid leukemia cells 97
Targeting CREB in Cancer Therapy: A Key Candidate or One of Many? An Update 96
Histidine degradation enzymes in rat liver: induction by high protein intake 93
The effect on adenylate cyclase (AC) system of in vivo treatment with inorganic phosphate on osteoblasts during differentiation 91
GTPase and transglutaminase are associated in the secretion of the rat anterior prostate 90
Steroid receptors in epithelial ovarian carcinoma: relation to clinical parameters and survival 90
In vivo treatment by retinoic aci (RA) triggers early interaction among protein kinase activity in ras-virus transformed cells 90
Effect of carnitine on heart alterations caused by tricyclic antidepressants 88
In vitro phosphorylation of high molecular weight glutenin subunits from wheat endosperm 85
Phosphorylation of Wheat Gluteinin Subunits 80
Protein kinase C and G proteins 75
Totale 12.413
Categoria #
all - tutte 41.041
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 41.041


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022615 0 3 10 20 217 9 6 33 25 54 64 174
2022/20231.562 108 58 16 166 171 136 2 89 719 27 31 39
2023/2024442 57 17 19 40 138 36 7 13 7 3 45 60
2024/20251.334 3 4 21 35 247 222 239 111 170 128 94 60
2025/20265.722 256 185 292 259 441 3.283 292 237 177 132 77 91
2026/2027135 37 98 0 0 0 0 0 0 0 0 0 0
Totale 12.413