IRIS
SPINA, Annamaria
 Distribuzione geografica
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Continente #
EU - Europa 6.173
NA - Nord America 4.033
AS - Asia 2.274
Continente sconosciuto - Info sul continente non disponibili 426
SA - Sud America 296
AF - Africa 26
OC - Oceania 5
Totale 13.233
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Nazione #
US - Stati Uniti d'America 3.939
RU - Federazione Russa 3.472
SG - Singapore 847
IE - Irlanda 719
IT - Italia 653
CN - Cina 524
HK - Hong Kong 339
UA - Ucraina 326
GB - Regno Unito 299
DE - Germania 278
BR - Brasile 251
VN - Vietnam 199
FI - Finlandia 104
SE - Svezia 102
KR - Corea 98
IN - India 89
FR - Francia 68
TR - Turchia 57
GR - Grecia 55
CA - Canada 46
BD - Bangladesh 43
JP - Giappone 24
MX - Messico 24
BE - Belgio 20
AR - Argentina 18
NL - Olanda 17
AT - Austria 11
ES - Italia 9
IQ - Iraq 9
ZA - Sudafrica 9
PL - Polonia 8
RO - Romania 8
EC - Ecuador 7
ID - Indonesia 7
CR - Costa Rica 6
CL - Cile 5
IR - Iran 5
MA - Marocco 5
PK - Pakistan 5
AU - Australia 4
BG - Bulgaria 4
CO - Colombia 4
LT - Lituania 4
NO - Norvegia 4
VE - Venezuela 4
BO - Bolivia 3
BS - Bahamas 3
EE - Estonia 3
HU - Ungheria 3
JO - Giordania 3
KZ - Kazakistan 3
PH - Filippine 3
PR - Porto Rico 3
PT - Portogallo 3
TH - Thailandia 3
UY - Uruguay 3
UZ - Uzbekistan 3
AE - Emirati Arabi Uniti 2
CH - Svizzera 2
EG - Egitto 2
EU - Europa 2
HN - Honduras 2
JM - Giamaica 2
NP - Nepal 2
SV - El Salvador 2
TN - Tunisia 2
TT - Trinidad e Tobago 2
AM - Armenia 1
AO - Angola 1
AZ - Azerbaigian 1
CY - Cipro 1
CZ - Repubblica Ceca 1
DO - Repubblica Dominicana 1
DZ - Algeria 1
ET - Etiopia 1
GA - Gabon 1
GT - Guatemala 1
IL - Israele 1
KE - Kenya 1
KG - Kirghizistan 1
KH - Cambogia 1
KY - Cayman, isole 1
MU - Mauritius 1
NZ - Nuova Zelanda 1
OM - Oman 1
PA - Panama 1
PY - Paraguay 1
SA - Arabia Saudita 1
SC - Seychelles 1
SN - Senegal 1
TW - Taiwan 1
Totale 12.809
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Città #
Moscow 1.162
Dublin 716
Jacksonville 492
Chandler 465
Santa Clara 397
Singapore 388
San Jose 336
Hong Kong 333
Ashburn 260
Caserta 259
Council Bluffs 221
Princeton 99
Seoul 91
Ann Arbor 85
Beijing 85
Medford 75
Bremen 70
Milan 66
Boardman 64
Ho Chi Minh City 60
Hanoi 56
New York 54
San Mateo 51
Wilmington 50
Bengaluru 48
Roxbury 46
Woodbridge 39
Hefei 38
Dallas 34
Munich 32
Naples 30
Cambridge 29
The Dalles 25
Los Angeles 22
Nanjing 20
Orem 20
Brussels 19
Düsseldorf 19
Rome 19
Houston 18
Mountain View 18
Napoli 18
Des Moines 17
São Paulo 16
Frankfurt am Main 15
Da Nang 14
Jinan 13
Miano 13
Turku 12
Atlanta 11
Helsinki 11
Auburn Hills 10
North Bergen 10
Zhengzhou 10
Tianjin 9
Belo Horizonte 8
Chicago 8
Haiphong 8
Memphis 8
Mexico 8
Mexico City 8
Montreal 8
Tokyo 8
Toronto 8
Boston 7
Brooklyn 7
Giugliano In Campania 7
Nuremberg 7
Ottawa 7
San Francisco 7
Changsha 6
Chennai 6
Dong Ket 6
Guangzhou 6
Hangzhou 6
Johannesburg 6
Kochi 6
London 6
Manchester 6
Mirabella Eclano 6
Warsaw 6
Afragola 5
Amsterdam 5
Bologna 5
Columbus 5
Florence 5
Jakarta 5
Mumbai 5
New Delhi 5
Norwalk 5
Orta di Atella 5
Phoenix 5
Rio de Janeiro 5
San Diego 5
San José 5
Seattle 5
Venice 5
Vienna 5
Wuhan 5
Aversa 4
Totale 6.864
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Nome #
Histone deacetylase inhibitors increase p27Kip1 by affecting its ubiquitin-dependent degradation through Skp2 down-regulation 267
Lactic dehydrogenase and cancer: an overview 228
Adiponectin down-regulates CREB and inhibits proliferation of A549 lung cancer cells 220
cAMP elevation down-regulates beta3 integrin and Focal Adhesion Kinase and inhibits leptin-induced migration of MDA-MB-231 breast cancer cells 212
Forskolin potentiates the effects of GSKJ4 in human acute myeloid leukemia cells through Protein Kinase A pathway 207
Chlorogenic acid activates ERK1/2 and inhibits proliferation of osteosarcoma cells 205
Adenylate cyclase/cAMP pathway downmodulation counteracts apoptosis induced by IFN-alpha in human epidermoid cancer cells. 201
5-Fluorouracil induces apoptosis in rat cardiocytes through intracellular oxidative stress. 197
S-Adenosylmethionine Affects ERK1/2 and STAT3 Pathways and Induces Apoptosis in Osteosarcoma Cells. 196
A novel G-protein active on signal transduction 196
The Natural cAMP Elevating Compound Forskolin in Cancer Therapy: Is it Time? 196
Change in TNF-alpha receptor expression is a relevant event in doxorubicin-induced H9c2 cardiomyocyte cell death 187
Adenylate Cyclase modulation by proteasome mediated αs accumulation in mammalian cells 185
A stimulating effect of guanyl nucleotides on the rat-liver soluble cyclic GMP high-affinity phosphodiesterase activity 180
Forskolin improves sensitivity to doxorubicin of triple negative breast cancer cells via Protein Kinase A-mediated ERK1/2 inhibition 180
Chlorogenic acid enhances doxorubicin-mediated cytotoxic effect in osteosarcoma cells 175
Adenylate cyclase regulation via proteasome-mediated modulation of Galphas levels. 174
cAMP pathway in differentiating myoblast 172
Inorganic Phosphate Prevents Erk1/2 and Stat3 Activation and Improves Sensitivity to Doxorubicin of MDA-MB-231 Breast Cancer Cells 172
Cellular response to PCL/ZrO2hybrid materials synthesized via sol-gel as a function of PCL content 172
An in vitro model for dissecting distraction osteogenesis 169
Doxorubicin (DXR) treatment stimulates TNF-α expression in the rat cardiomyoblast cell line (H9c2), triggering mechanisms of auto-toxicity 169
Differentiation of H9c2 cardiomyoblasts: The role of adenylate cyclase system. 168
Gli effetti della fosforilazione di proteine di membrana, PKC mediata, sull’attività adenilato ciclasica di piastrine umane 166
AdipoRon Affects Cell Cycle Progression and Inhibits Proliferation in Human Osteosarcoma Cells 164
Forskolin affects proliferation, migration and Paclitaxel-mediated cytotoxicity in non-small-cell lung cancer cell lines via adenylyl cyclase/cAMP axis 161
Adenylate Cyclase activity in rat thyroid epithelial cells (PC-Cl3) treated in vivo with lovastatin 158
Adenylate cyclase and cell cycle 157
Targeting protein kinase A in cancer therapy: an update. 155
G-Protein modulation of the adenylate cyclase (AC) activity in control and Ras-virus transformed epithelial cells. 153
Cholera toxin-mediated ADP-ribosylation " in vivo ": A useful tool for studying the G-protein cycle. 152
Forskolin sensitizes pancreatic cancer cells to gemcitabine via Stat3 and Erk1/2 inhibition 152
AdipoRon and Pancreatic Ductal Adenocarcinoma: a future perspective in overcoming chemotherapy-induced resistance? 149
Anoxia-inducible endonuclease activity as a potential basis of the genomic instability of cancer cells 145
INHIBITION OF ONCOGENIC EFFECTS OF LEPTIN BY CAMP ELEVATION IN TRIPLE NEGATIVE BREAST CANCER CELLS 142
Targeting p27Kip1 protein: its relevance in the therapy of human cancer. 142
Ubiquitin/proteasome system and adenylate cyclase: their functional interrelations 139
Leptin enhances growth inhibition by cAMP elevating agents through apoptosis of MDA-MB-231 breast cancer cells 137
Inorganic phosphate enhances sensitivity of human osteosarcoma U2OS cells to doxorubicin via a p53-dependent pathway. 137
Treatment of v-Ki-ras-transformed SVC1 cells with low retinoic acid induces malignancy reversion associated with ras p21 down-regulation 136
Integrating Gemcitabine-Based Therapy With AdipoRon Enhances Growth Inhibition in Human PDAC Cell Lines 134
Increased adenylate cyclase activity in rat thyroid epithelial cells expressing viral ras genes 133
The influence of the polymer amount on the biological properties of PCL/ZrO2hybrid materials synthesized via sol-gel technique 133
Inorganic phosphate as a new signalling molecule: effects on the adenylate cyclase/cAMP system 132
Retinoic acid modulates external signal metabolic pathways in SVCI and KiSVC1 epithelial cells. 131
Adriamycin causes hyperlipemia as a consequence of nephrotoxicity 130
Valutazioni di metodiche di criopreservazione di piastrine umane sulla base di parametri fisici, biochimici e funzionali 130
Synergistic cytotoxic effects of inorganic phosphate and chemotherapeutic drugs on human osteosarcoma cells. 130
Protein Kinase A as a biological target in cancer therapy. 129
Forskolin sensitizes human acute myeloid leukemia cells to H3K27me2/3 demethylases GSKJ4 inhibitor via Protein Kinase A 129
Inorganic phosphate inhibits growth of human osteosarcoma U2OS cells via adenylate cyclase/cAMP pathway 128
TNF-alpha receptors expression level changes are a relevant event in Doxorubicin-induced H9c2 cardiomyocytes apoptosis 128
Pleiotropic biochemical effects of retinoic acid: are they functionally correlated? 127
Inorganic Phosphate as A Signaling Molecule: A Potential Strategy in Osteosarcoma Treatment 127
The phosphorylation degree of the proteins in the neoplastic epidermoid A431 cells is also affected by a Ca2+-calmodulin dependent modulation. 126
INORGANIC PHOSPHATE AS A NOVEL SIGNALING MOLECULE: ITS POTENTIAL USE IN THE OSTEOSARCOMA THERAPY 126
Leptin affects adenylate cyclase activity in H9c2 cardiac cell line: effects of short- and long-term exsposure 124
LEPTIN POTENTIATES ANTIPROLIFERATIVE ACTION OF cAPM ELEVATION VIA PROTEIN KINASE A DOWN-REGULATION IN BREAST CANCER CELLS. 123
Inorganic phosphate as a novel signalling molecule with antiproliferative action in MDA-MB-231 breast cancer cells 123
Integrating leptin and cAMP signalling pathways in triple-negative breast cancer cells. 123
Tissue Transglutaminase and adenylate cyclase interactions in balb-C 3T3 fibroblast membranes 123
Regulatory mechanism of the soluble phosphodiesterase activities in rat liver. 122
Low insulin concentrations stimulate in vitro the soluble guanylate cyclase activity of rat liver. 121
Leptin effect on adenylate cyclase/cAMP pathway in rat H9c2 myoblasts 121
Meccanismi di regolazione delle attività fosfodiesterasiche in fegato di ratto 121
Functional implications of human tissue transglutaminase in the modulation of signal transduction via G-proteins 120
GTPase activity of Transglutaminase secreted from rat coagulation gland 120
ras oncogene-induced transformation of a rat seminal vesicle epithelial cell line produces a marked increase of adenylate cyclase and protein kinase C activities. 119
Protein kinase activities in epidermoid cells (A431) 117
Effect of vitamin C on pre-osteoblast gene expression 117
Role of calcium in chloride secretion mediated by cAMP pathway activation in rabbit distal colon mucosa 117
Protein kinase a detection in human urine samples 116
The effects of membrane protein phosphorilation on the bound adenylate cyclase activity in crude preparation of brain membranes 114
Novel molecular mechanisms by inorganic phosphate in osteosarcoma U2OS cells 113
Early effects by retinoic acid (RA) at the membrane level in eucaryotic cells. 112
Leptin effects on rat cardiomyocytes: a possible involvement of cAMP signal transduction pathway in heart failure development 112
Protein kinase C activities are increased in rat thyroid epithelial cells expressing V-ras genes 111
tTGase/G alpha h protein expression inhibits adenylate cyclase activity in Balb-C 3T3 fibroblasts membranes 110
Relationships between doxorubicin (Doxo)-induced damage and TNF-α pathways in H9c2 cardiomyoblast 108
Interaction between f- and cholera toxin " in vivo " ADP-ribosilation on the adenylate cyclase acyivity modulation. 108
The effects of polyamines on the cyclic AMP efflux and metabolism in E. coli B cells 107
Targeting CREB in Cancer Therapy: A Key Candidate or One of Many? An Update 106
Histidine degradation enzymes in rat liver: induction by high protein intake 104
Role of extracellular Ca++ in PGE2 mediated chloride secretion across rabbit distal colon mucosa 104
GTP-binding proteins and protein kinase C activities (PK). 103
The KDM inhibitor GSKJ4 triggers CREB down-regulation via a protein kinase A and proteasome dependent mechanism in human acute myeloid leukemia cells 102
The effect on adenylate cyclase (AC) system of in vivo treatment with inorganic phosphate on osteoblasts during differentiation 98
Steroid receptors in epithelial ovarian carcinoma: relation to clinical parameters and survival 98
GTPase and transglutaminase are associated in the secretion of the rat anterior prostate 97
In vivo treatment by retinoic aci (RA) triggers early interaction among protein kinase activity in ras-virus transformed cells 96
In vitro phosphorylation of high molecular weight glutenin subunits from wheat endosperm 94
Effect of carnitine on heart alterations caused by tricyclic antidepressants 93
Phosphorylation of Wheat Gluteinin Subunits 87
Protein kinase C and G proteins 83
Totale 13.233
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Categoria #
all - tutte 43.378
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 43.378
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022602 0 0 0 20 217 9 6 33 25 54 64 174
2022/20231.562 108 58 16 166 171 136 2 89 719 27 31 39
2023/2024442 57 17 19 40 138 36 7 13 7 3 45 60
2024/20251.334 3 4 21 35 247 222 239 111 170 128 94 60
2025/20265.722 256 185 292 259 441 3.283 292 237 177 132 77 91
2026/2027955 37 143 431 344 0 0 0 0 0 0 0 0
Totale 13.233