IRIS
SPINA, Annamaria
 Distribuzione geografica
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Continente #
EU - Europa 5.465
NA - Nord America 2.772
AS - Asia 1.850
SA - Sud America 282
AF - Africa 22
OC - Oceania 4
Continente sconosciuto - Info sul continente non disponibili 2
Totale 10.397
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Nazione #
RU - Federazione Russa 2.976
US - Stati Uniti d'America 2.728
IE - Irlanda 717
SG - Singapore 716
IT - Italia 501
CN - Cina 466
UA - Ucraina 325
HK - Hong Kong 323
GB - Regno Unito 289
DE - Germania 269
BR - Brasile 242
FI - Finlandia 103
SE - Svezia 101
KR - Corea 95
IN - India 67
FR - Francia 63
VN - Vietnam 59
TR - Turchia 56
GR - Grecia 53
CA - Canada 21
BE - Belgio 19
JP - Giappone 19
MX - Messico 19
AR - Argentina 17
BD - Bangladesh 10
AT - Austria 9
NL - Olanda 9
IQ - Iraq 8
ZA - Sudafrica 7
EC - Ecuador 6
ID - Indonesia 6
PL - Polonia 6
CL - Cile 5
ES - Italia 5
IR - Iran 5
MA - Marocco 5
NO - Norvegia 4
RO - Romania 4
VE - Venezuela 4
AU - Australia 3
BG - Bulgaria 3
BO - Bolivia 3
HU - Ungheria 3
JO - Giordania 3
PT - Portogallo 3
UY - Uruguay 3
AE - Emirati Arabi Uniti 2
EG - Egitto 2
EU - Europa 2
KZ - Kazakistan 2
LT - Lituania 2
PK - Pakistan 2
TN - Tunisia 2
UZ - Uzbekistan 2
AM - Armenia 1
AO - Angola 1
AZ - Azerbaigian 1
CH - Svizzera 1
CO - Colombia 1
CR - Costa Rica 1
DO - Repubblica Dominicana 1
DZ - Algeria 1
ET - Etiopia 1
GA - Gabon 1
IL - Israele 1
KE - Kenya 1
KG - Kirghizistan 1
KH - Cambogia 1
KY - Cayman, isole 1
NP - Nepal 1
NZ - Nuova Zelanda 1
OM - Oman 1
PA - Panama 1
PH - Filippine 1
PY - Paraguay 1
SA - Arabia Saudita 1
SN - Senegal 1
Totale 10.397
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Città #
Moscow 974
Dublin 714
Jacksonville 491
Chandler 465
Santa Clara 364
Hong Kong 321
Singapore 310
Caserta 259
Princeton 92
Seoul 89
Ann Arbor 85
Beijing 81
Medford 75
Bremen 70
Ashburn 65
Boardman 63
San Mateo 51
Wilmington 50
Bengaluru 48
Roxbury 46
New York 39
Woodbridge 39
Hefei 38
Munich 32
Cambridge 29
Dallas 28
Naples 25
The Dalles 24
Nanjing 20
Brussels 19
Düsseldorf 19
Ho Chi Minh City 18
Mountain View 18
Napoli 18
Des Moines 17
Hanoi 16
Houston 15
Los Angeles 14
Jinan 13
Rome 13
São Paulo 13
Turku 12
Frankfurt am Main 11
Milan 11
Auburn Hills 10
Helsinki 10
Zhengzhou 10
Tianjin 9
Belo Horizonte 8
Mexico 8
Boston 7
Giugliano In Campania 7
Nuremberg 7
Brooklyn 6
Changsha 6
Dong Ket 6
Guangzhou 6
Hangzhou 6
Mirabella Eclano 6
Ottawa 6
Toronto 6
Jakarta 5
Johannesburg 5
London 5
Norwalk 5
Rio de Janeiro 5
Venice 5
Wuhan 5
Aversa 4
Campinas 4
Chicago 4
Columbus 4
Curitiba 4
Fortaleza 4
Haiphong 4
Hanover 4
Hyderabad 4
Lanzhou 4
Mexico City 4
Ningbo 4
Oslo 4
Phoenix 4
Redwood City 4
Salvador 4
San Vitaliano 4
Shenzhen 4
Vienna 4
Warsaw 4
Amman 3
Avellino 3
Baghdad 3
Belém 3
Brasília 3
Buk-gu 3
Cachoeirinha 3
Contagem 3
Dhaka 3
Elora 3
Fairfield 3
Groningen 3
Totale 5.489
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Nome #
Histone deacetylase inhibitors increase p27Kip1 by affecting its ubiquitin-dependent degradation through Skp2 down-regulation 225
Lactic dehydrogenase and cancer: an overview 193
Adiponectin down-regulates CREB and inhibits proliferation of A549 lung cancer cells 192
cAMP elevation down-regulates beta3 integrin and Focal Adhesion Kinase and inhibits leptin-induced migration of MDA-MB-231 breast cancer cells 171
Chlorogenic acid activates ERK1/2 and inhibits proliferation of osteosarcoma cells 171
S-Adenosylmethionine Affects ERK1/2 and STAT3 Pathways and Induces Apoptosis in Osteosarcoma Cells. 169
Adenylate cyclase/cAMP pathway downmodulation counteracts apoptosis induced by IFN-alpha in human epidermoid cancer cells. 169
5-Fluorouracil induces apoptosis in rat cardiocytes through intracellular oxidative stress. 164
The Natural cAMP Elevating Compound Forskolin in Cancer Therapy: Is it Time? 164
A novel G-protein active on signal transduction 162
Change in TNF-alpha receptor expression is a relevant event in doxorubicin-induced H9c2 cardiomyocyte cell death 159
Forskolin improves sensitivity to doxorubicin of triple negative breast cancer cells via Protein Kinase A-mediated ERK1/2 inhibition 157
A stimulating effect of guanyl nucleotides on the rat-liver soluble cyclic GMP high-affinity phosphodiesterase activity 152
Adenylate Cyclase modulation by proteasome mediated αs accumulation in mammalian cells 151
cAMP pathway in differentiating myoblast 146
Adenylate cyclase regulation via proteasome-mediated modulation of Galphas levels. 146
An in vitro model for dissecting distraction osteogenesis 144
Doxorubicin (DXR) treatment stimulates TNF-α expression in the rat cardiomyoblast cell line (H9c2), triggering mechanisms of auto-toxicity 143
Forskolin potentiates the effects of GSKJ4 in human acute myeloid leukemia cells through Protein Kinase A pathway 143
Cellular response to PCL/ZrO2hybrid materials synthesized via sol-gel as a function of PCL content 142
Inorganic Phosphate Prevents Erk1/2 and Stat3 Activation and Improves Sensitivity to Doxorubicin of MDA-MB-231 Breast Cancer Cells 141
Differentiation of H9c2 cardiomyoblasts: The role of adenylate cyclase system. 140
AdipoRon Affects Cell Cycle Progression and Inhibits Proliferation in Human Osteosarcoma Cells 138
Chlorogenic acid enhances doxorubicin-mediated cytotoxic effect in osteosarcoma cells 138
Adenylate cyclase and cell cycle 135
Adenylate Cyclase activity in rat thyroid epithelial cells (PC-Cl3) treated in vivo with lovastatin 134
Gli effetti della fosforilazione di proteine di membrana, PKC mediata, sull’attività adenilato ciclasica di piastrine umane 132
Forskolin sensitizes pancreatic cancer cells to gemcitabine via Stat3 and Erk1/2 inhibition 132
Forskolin affects proliferation, migration and Paclitaxel-mediated cytotoxicity in non-small-cell lung cancer cell lines via adenylyl cyclase/cAMP axis 129
Targeting protein kinase A in cancer therapy: an update. 128
Cholera toxin-mediated ADP-ribosylation " in vivo ": A useful tool for studying the G-protein cycle. 128
G-Protein modulation of the adenylate cyclase (AC) activity in control and Ras-virus transformed epithelial cells. 128
AdipoRon and Pancreatic Ductal Adenocarcinoma: a future perspective in overcoming chemotherapy-induced resistance? 122
Leptin enhances growth inhibition by cAMP elevating agents through apoptosis of MDA-MB-231 breast cancer cells 118
Anoxia-inducible endonuclease activity as a potential basis of the genomic instability of cancer cells 117
INHIBITION OF ONCOGENIC EFFECTS OF LEPTIN BY CAMP ELEVATION IN TRIPLE NEGATIVE BREAST CANCER CELLS 117
Increased adenylate cyclase activity in rat thyroid epithelial cells expressing viral ras genes 116
Targeting p27Kip1 protein: its relevance in the therapy of human cancer. 116
The influence of the polymer amount on the biological properties of PCL/ZrO2hybrid materials synthesized via sol-gel technique 115
Inorganic phosphate enhances sensitivity of human osteosarcoma U2OS cells to doxorubicin via a p53-dependent pathway. 114
Adriamycin causes hyperlipemia as a consequence of nephrotoxicity 112
Treatment of v-Ki-ras-transformed SVC1 cells with low retinoic acid induces malignancy reversion associated with ras p21 down-regulation 111
Ubiquitin/proteasome system and adenylate cyclase: their functional interrelations 111
Integrating Gemcitabine-Based Therapy With AdipoRon Enhances Growth Inhibition in Human PDAC Cell Lines 110
Inorganic phosphate as a new signalling molecule: effects on the adenylate cyclase/cAMP system 108
Synergistic cytotoxic effects of inorganic phosphate and chemotherapeutic drugs on human osteosarcoma cells. 108
Retinoic acid modulates external signal metabolic pathways in SVCI and KiSVC1 epithelial cells. 107
Inorganic Phosphate as A Signaling Molecule: A Potential Strategy in Osteosarcoma Treatment 105
Forskolin sensitizes human acute myeloid leukemia cells to H3K27me2/3 demethylases GSKJ4 inhibitor via Protein Kinase A 105
The phosphorylation degree of the proteins in the neoplastic epidermoid A431 cells is also affected by a Ca2+-calmodulin dependent modulation. 104
Low insulin concentrations stimulate in vitro the soluble guanylate cyclase activity of rat liver. 102
INORGANIC PHOSPHATE AS A NOVEL SIGNALING MOLECULE: ITS POTENTIAL USE IN THE OSTEOSARCOMA THERAPY 102
Pleiotropic biochemical effects of retinoic acid: are they functionally correlated? 102
Inorganic phosphate inhibits growth of human osteosarcoma U2OS cells via adenylate cyclase/cAMP pathway 101
Inorganic phosphate as a novel signalling molecule with antiproliferative action in MDA-MB-231 breast cancer cells 101
Regulatory mechanism of the soluble phosphodiesterase activities in rat liver. 100
Protein Kinase A as a biological target in cancer therapy. 99
Meccanismi di regolazione delle attività fosfodiesterasiche in fegato di ratto 99
ras oncogene-induced transformation of a rat seminal vesicle epithelial cell line produces a marked increase of adenylate cyclase and protein kinase C activities. 98
Leptin effect on adenylate cyclase/cAMP pathway in rat H9c2 myoblasts 98
Valutazioni di metodiche di criopreservazione di piastrine umane sulla base di parametri fisici, biochimici e funzionali 98
Tissue Transglutaminase and adenylate cyclase interactions in balb-C 3T3 fibroblast membranes 98
TNF-alpha receptors expression level changes are a relevant event in Doxorubicin-induced H9c2 cardiomyocytes apoptosis 97
Leptin affects adenylate cyclase activity in H9c2 cardiac cell line: effects of short- and long-term exsposure 97
LEPTIN POTENTIATES ANTIPROLIFERATIVE ACTION OF cAPM ELEVATION VIA PROTEIN KINASE A DOWN-REGULATION IN BREAST CANCER CELLS. 97
Integrating leptin and cAMP signalling pathways in triple-negative breast cancer cells. 97
Protein kinase activities in epidermoid cells (A431) 96
Role of calcium in chloride secretion mediated by cAMP pathway activation in rabbit distal colon mucosa 96
Functional implications of human tissue transglutaminase in the modulation of signal transduction via G-proteins 95
The effects of membrane protein phosphorilation on the bound adenylate cyclase activity in crude preparation of brain membranes 95
Novel molecular mechanisms by inorganic phosphate in osteosarcoma U2OS cells 95
Protein kinase C activities are increased in rat thyroid epithelial cells expressing V-ras genes 94
tTGase/G alpha h protein expression inhibits adenylate cyclase activity in Balb-C 3T3 fibroblasts membranes 90
Early effects by retinoic acid (RA) at the membrane level in eucaryotic cells. 90
GTPase activity of Transglutaminase secreted from rat coagulation gland 89
Interaction between f- and cholera toxin " in vivo " ADP-ribosilation on the adenylate cyclase acyivity modulation. 88
Leptin effects on rat cardiomyocytes: a possible involvement of cAMP signal transduction pathway in heart failure development 88
Role of extracellular Ca++ in PGE2 mediated chloride secretion across rabbit distal colon mucosa 87
GTP-binding proteins and protein kinase C activities (PK). 86
The KDM inhibitor GSKJ4 triggers CREB down-regulation via a protein kinase A and proteasome dependent mechanism in human acute myeloid leukemia cells 83
Protein kinase a detection in human urine samples 82
GTPase and transglutaminase are associated in the secretion of the rat anterior prostate 81
Histidine degradation enzymes in rat liver: induction by high protein intake 81
Targeting CREB in Cancer Therapy: A Key Candidate or One of Many? An Update 81
Effect of vitamin C on pre-osteoblast gene expression 80
The effects of polyamines on the cyclic AMP efflux and metabolism in E. coli B cells 80
The effect on adenylate cyclase (AC) system of in vivo treatment with inorganic phosphate on osteoblasts during differentiation 78
Steroid receptors in epithelial ovarian carcinoma: relation to clinical parameters and survival 78
Relationships between doxorubicin (Doxo)-induced damage and TNF-α pathways in H9c2 cardiomyoblast 76
In vivo treatment by retinoic aci (RA) triggers early interaction among protein kinase activity in ras-virus transformed cells 76
Effect of carnitine on heart alterations caused by tricyclic antidepressants 76
In vitro phosphorylation of high molecular weight glutenin subunits from wheat endosperm 72
Phosphorylation of Wheat Gluteinin Subunits 71
Protein kinase C and G proteins 69
Totale 10.821
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Categoria #
all - tutte 35.213
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 35.213
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021426 0 0 0 0 0 37 109 79 9 96 71 25
2021/2022669 54 3 10 20 217 9 6 33 25 54 64 174
2022/20231.562 108 58 16 166 171 136 2 89 719 27 31 39
2023/2024442 57 17 19 40 138 36 7 13 7 3 45 60
2024/20251.334 3 4 21 35 247 222 239 111 170 128 94 60
2025/20264.265 256 185 292 259 441 2.832 0 0 0 0 0 0
Totale 10.821