IRIS
GUIDA, Francesca
 Distribuzione geografica
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Continente #
EU - Europa 6.746
NA - Nord America 4.219
AS - Asia 3.243
SA - Sud America 405
Continente sconosciuto - Info sul continente non disponibili 281
AF - Africa 35
OC - Oceania 4
Totale 14.933
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Nazione #
RU - Federazione Russa 4.180
US - Stati Uniti d'America 4.128
SG - Singapore 1.038
CN - Cina 777
IT - Italia 728
IE - Irlanda 668
VN - Vietnam 461
HK - Hong Kong 363
BR - Brasile 324
DE - Germania 280
GB - Regno Unito 238
UA - Ucraina 238
KR - Corea 154
TR - Turchia 124
JP - Giappone 113
FI - Finlandia 86
IN - India 85
GR - Grecia 62
SE - Svezia 62
FR - Francia 52
CA - Canada 51
AR - Argentina 30
PL - Polonia 27
CZ - Repubblica Ceca 21
NL - Olanda 20
BE - Belgio 19
BD - Bangladesh 18
EC - Ecuador 17
IQ - Iraq 17
MX - Messico 17
AT - Austria 15
ID - Indonesia 13
ES - Italia 11
LB - Libano 10
PK - Pakistan 10
PT - Portogallo 10
UZ - Uzbekistan 10
ZA - Sudafrica 9
PE - Perù 8
CO - Colombia 7
PY - Paraguay 7
JM - Giamaica 6
MA - Marocco 6
SA - Arabia Saudita 6
AE - Emirati Arabi Uniti 5
CL - Cile 5
CR - Costa Rica 5
JO - Giordania 5
DK - Danimarca 4
DO - Repubblica Dominicana 4
IL - Israele 4
IR - Iran 4
LT - Lituania 4
NP - Nepal 4
NZ - Nuova Zelanda 4
RO - Romania 4
UY - Uruguay 4
BH - Bahrain 3
HU - Ungheria 3
OM - Oman 3
PH - Filippine 3
TN - Tunisia 3
TW - Taiwan 3
VE - Venezuela 3
AL - Albania 2
AO - Angola 2
AZ - Azerbaigian 2
CH - Svizzera 2
DZ - Algeria 2
EG - Egitto 2
KE - Kenya 2
KW - Kuwait 2
KZ - Kazakistan 2
LY - Libia 2
MK - Macedonia 2
NG - Nigeria 2
NI - Nicaragua 2
SI - Slovenia 2
TT - Trinidad e Tobago 2
A1 - Anonimo 1
BF - Burkina Faso 1
BS - Bahamas 1
BW - Botswana 1
BZ - Belize 1
CG - Congo 1
CY - Cipro 1
ET - Etiopia 1
EU - Europa 1
GE - Georgia 1
GT - Guatemala 1
HR - Croazia 1
IM - Isola di Man 1
MD - Moldavia 1
MQ - Martinica 1
MT - Malta 1
NO - Norvegia 1
PS - Palestinian Territory 1
SK - Slovacchia (Repubblica Slovacca) 1
SN - Senegal 1
SY - Repubblica araba siriana 1
Totale 14.654
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Città #
Moscow 1.440
Dublin 663
Singapore 520
San Jose 467
Chandler 415
Santa Clara 395
Hong Kong 357
Jacksonville 335
Ashburn 268
Council Bluffs 215
Beijing 173
Seoul 154
Ho Chi Minh City 153
Naples 122
Hefei 117
Hanoi 109
Bremen 85
Princeton 81
Dallas 77
Ann Arbor 75
Medford 67
Boardman 62
Munich 62
Wilmington 62
New York 59
Bengaluru 58
Roxbury 56
Dearborn 55
Caserta 46
Cava 46
Mugnano di Napoli 43
Aversa 42
Los Angeles 42
The Dalles 41
Woodbridge 38
Rome 35
Kunming 29
San Mateo 28
Da Nang 26
São Paulo 26
Cambridge 25
Dong Ket 24
Milan 24
Nanjing 24
Des Moines 23
Jinan 23
Haiphong 22
Houston 22
Chicago 20
Brussels 19
Turku 19
Brno 18
Guangzhou 17
Istanbul 17
Orem 17
Frankfurt am Main 16
Helsinki 16
Napoli 16
Volla 16
Norwalk 15
San Francisco 14
Belo Horizonte 13
Falkenstein 13
Kayseri 12
Krakow 12
Viterbo 12
Atlanta 11
Brooklyn 11
Bến Tre 11
Düsseldorf 11
Memphis 11
Mexico City 11
Shanghai 11
Tokyo 11
Amsterdam 10
Biên Hòa 10
Columbus 10
Hải Dương 10
Mountain View 10
Redwood City 10
Rio de Janeiro 10
Warsaw 10
Zhengzhou 10
Baghdad 9
Chennai 9
Hanover 9
Montreal 9
Nuremberg 9
Tashkent 9
Afragola 8
Miami 8
Paris 8
Quito 8
Toronto 8
Brasília 7
Denver 7
Florence 7
London 7
Parma 7
Shenyang 7
Totale 7.927
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Nome #
D-Aspartate drinking solution alleviates pain and cognitive impairment in neuropathic mice. 235
2-pentadecyl-2-oxazoline prevents cognitive and social behaviour impairments in the Amyloid β-induced Alzheimer-like mice model: Bring the α2 adrenergic receptor back into play 219
Evaluation of unsulfated biotechnological chondroitin in a knee osteoarthritis mouse model as a potential novel functional ingredient in nutraceuticals and pharmaceuticals 203
Dorsal striatum metabotropic glutamate receptor 8 affects nocifensive responses and rostral ventromedial medulla cell activity in neuropathic pain conditions. 201
5'-Chloro-5'-deoxy-(±)-ENBA, a potent and selective adenosine A(1) receptor agonist, alleviates neuropathic pain in mice through functional glial and microglial changes without affecting motor or cardiovascular functions. Molecules. 201
Chalcone derivatives activate and desensitize the transient receptor potential ankyrin 1 cation channel, subfamily A, member 1 TRPA1 ion channel: structure-activity relationships in vitro and anti-nociceptive and anti-inflammatory activity in vivo 201
Changes in cannabinoid receptor subtype 1 activity and interaction with metabotropic glutamate subtype 5 receptors in the periaqueductal gray-rostral ventromedial medulla pathway in a rodent neuropathic pain model. 200
Palmitoylethanolamide reduces pain-related behaviors and restores glutamatergic synapses homeostasis in the medial prefrontal cortex of neuropathic mice 196
D-aspartate modulates nociceptive-specific neuron activity and pain threshold in inflammatory and neuropathic pain condition in mice 196
Behavioral, Biochemical and Electrophysiological Changes in Spared Nerve Injury Model of Neuropathic Pain 196
EP1 receptor within the ventrolateral periaqueductal grey controls thermonociception and rostral ventromedial medulla cell activity in healthy and neuropathic rat 195
Long-term neuropathic pain behaviors correlate with synaptic plasticity and limbic circuit alteration: a comparative observational study in mice 194
Antibiotic-induced microbiota perturbation causes gut endocannabinoidome changes, hippocampal neuroglial reorganization and depression in mice 191
PC1, a non-peptide PKR1-preferring antagonist, reduces pain behavior and spinal neuronal sensitization in neuropathic mice. 187
d-Aspartic acid ameliorates painful and neuropsychiatric changes and reduces β-amyloid Aβ1-42 peptide in a long lasting model of neuropathic pain. 182
MED1/BDNF/TrkB pathway is involved in thalamic hemorrhage-induced pain and depression by regulating microglia 182
Design and Synthesis of New Transient Receptor Potential Vanilloid Type-1 (TRPV1) Channel Modulators: Identification, Molecular Modeling Analysis, and Pharmacological Characterization of the N-(4-Hydroxy-3-methoxybenzyl)-4-(thiophen-2-yl)butanamide, a Small Molecule Endowed with Agonist TRPV1 Activity and Protective Effects against Oxidative Stress. 180
Clinical determination of carbohydrate-deficient transferrin (CDT) in alcohol addicts: A random sample of the general population in Naples, Italy 180
Palmitoylethanolamide reduces neuropsychiatric behaviors by restoring cortical electrophysiological activity in a mouse model of mild traumatic brain injury 179
PEA-OXA restores cognitive impairments associated with vitamin D deficiency-dependent alterations of the gut microbiota 178
Effect of Prolonged Moderate Exercise on the Changes of Nonneuronal Cells in Early Myocardial Infarction. 177
Exposure to allergen causes changes in nts neural activities after intratracheal capsaicin application, in endocannabinoid levels and in the glia morphology of nts 175
Amyloid-β-Induced Transglutaminase 2 Expression and Activities Are Modulated by 2-Pentadecyl-2-Oxazoline in Mouse and Human Microglial Cell Lines 174
Ultrapotent effects of salvinorin A, a hallucinogenic compound from Salvia divinorum, on LPS-stimulated murine macrophages and its anti-inflammatory action in vivo. 174
Metabotropic glutamate receptor subtype 7 in the dorsal striatum oppositely modulates pain in sham and neuropathic rats 170
Neuroimmune-driven neuropathic pain establishment: A focus on gender differences 169
5'-Chloro-5'-deoxy-(±)-ENBA, a potent and selective adenosine A1 receptor agonist, alleviates neuropathic pain in mice through functional glial and microglial changes without affecting motor or cardiovascular functions 167
Role of gut microbiota in neuropathy and neuropathic pain states: A systematic preclinical review 165
Vitamin d deficiency induces chronic pain and microglial phenotypic changes in mice 165
2-Pentadecyl-2-oxazoline ameliorates memory impairment and depression-like behaviour in neuropathic mice: possible role of adrenergic alpha2- and H3 histamine autoreceptors. 161
Document Effects of naltrexone treatment on hypothalamic-pituitary-adrenal axis activation and GABA release in rats 160
Effects of URB597, an inhibitor of fatty acid amide hydrolase (FAAH), on analgesic activity of paracetamol. 160
The 17-β-oestradiol inhibits osteoclast activity by increasing the cannabinoid CB2 receptor expression. 159
Palmitoylethanolamide induces microglia changes associated with increased migration and phagocytic activity: Involvement of the CB2 receptor 158
Identification of Cannabidiolic and Cannabigerolic Acids as MTDL AChE, BuChE, and BACE-1 Inhibitors Against Alzheimer's Disease by In Silico, In Vitro, and In Vivo Studies 157
Cannabidiol in traumatic brain injury 156
The cannabinoid receptor type 2 as mediator of mesenchymal stromal cell immunosuppressive properties. 156
Structural insight into the optimization of ethyl 5-hydroxybenzo[g] indol-3-carboxylates and their bioisosteric analogues as 5-LO/mPGES-1 dual inhibitors able to suppress inflammation 156
Pharmacological Considerations for the Use of General Anesthetics in the Elderly 155
The A1 adenosine receptor as a new player in microglia physiology 154
Salvinorin A reduces mechanical allodynia and spinal neuronal hyperexcitability induced by peripheral formalin injection. 154
The analgesic effect of N-arachidonoyl-serotonin, a FAAH inhibitor and TRPV1 receptor antagonist, associated with changes in rostral ventromedial medulla and locus coeruleus cell activity in rats 153
Design, synthesis, and pharmacological characterization of indol-3-ylacetamides, indol-3-yloxoacetamides, and indol-3-ylcarboxamides: potent and selective CB2 cannabinoid receptor inverse agonists. 153
Intraperiaqueductal gray glycine and D-serine exert dual effects on rostral ventromedial medulla ON- and OFF-cell activity and thermoceptive threshold in the rat 152
Intra-periaqueductal grey microinjections of an imidazo[1,2-b]pyridazine derivative, DM2, affects rostral ventromedial medulla cell activity and shows antinociceptive effect 151
Palmitoylethanolamide reduces formalin-induced neuropathic-like behaviour through spinal glial/microglial phenotypical changes in mice 151
The genetic ablation or pharmacological inhibition of TRPV1 signalling is beneficial for the restoration of quiescent osteoclast activity in ovariectomized mice. 150
The 17-estradiol inhibits osteoclast activity by increasing the cannabinoid CB2 receptor expression 148
Neuronutraceuticals Modulate Lipopolysaccharide- or Amyloid-β 1-42 Peptide-Induced Transglutaminase 2 Overexpression as a Marker of Neuroinflammation in Mouse Microglial Cells 148
Stealth liposomes encapsulating zoledronic acid: a new opportunity to treat neuropathic pain. 147
Spinal neuronal activity and neuroinflammatory component in a mouse model of CFA-induced vestibulodynia 146
Nociception modulation by supraspinal group III metabotropic glutamate receptors 146
Potential role of the hydroxyl carboxylic acid receptor type 2 (HCAR2) in microglia pathophysiology: A possible cross-talk with C-X-C chemokine receptor 1 (CXCR1) 145
Biphasic Hormetic-like Effect of Lebecetin, a C-type Lectin of Snake Venom, on Formalin-induced Inflammation in Mice 144
Adenosine Metabotropic Receptors in Chronic Pain Management 143
Effects of intra-ventrolateral periaqueductal grey palmitoylethanolamide on thermoceptive threshold and rostral ventromedial medulla cell activity 142
Early biomarkers in the presymptomatic phase of cognitive impairment: changes in the endocannabinoidome and serotonergic pathways in Alzheimer's-prone mice after mTBI 141
Effects of Palmitoylethanolamide (PEA) on Nociceptive, Musculoskeletal and Neuropathic Pain: Systematic Review and Meta-Analysis of Clinical Evidence 139
The long-term exercise after traumatic brain injury: Reharmonizing brain by sound body 138
Palvanil, a non-pungent capsaicin analogue, inhibits inflammatory and neuropathic pain with little effects on bronchopulmonary function and body temperature. 138
Synergistic effects of Boswellia serrata and Acmella oleracea extract combination for treating neuropathic pain in a preclinical model of spared nerve injury 137
Evaluation and cost analysis in two groups of patients who had been randomized for toxicological monitoring 137
N-palmitoyl-d-glucosamine, a natural monosaccharide-based glycolipid, inhibits tlr4 and prevents lps-induced inflammation and neuropathic pain in mice 137
New Insights on Neuropathic Pain Mechanisms as a Source for Novel Therapeutical Strategies 136
Periaqueductal gray metabotropic glutamate receptor subtype 7 and 8 mediate opposite effects on amino acid release, rostral ventromedial medulla cell activities, and thermal nociception 135
Enhanced serotonin and mesolimbic dopamine transmissions in a rat model of neuropathic pain. 135
Intra-Periaqueductal Gray glycine and D-serine exert dual effects on the Rostral Ventromedial Medulla ON and OFF cell activity and thermal threshold in the rat 134
Effects of adipose-derived mesenchymal stem cell conditioned medium on human tenocytes exposed to high glucose 133
Investigations on the 4-quinolone-3-carboxylic acid motif part 5: modulation of the physicochemical profile of a set of potent and selective cannabinoid-2 receptor ligands through a bioisosteric approach 133
N-Oleoyl-glycine reduces nicotine reward and withdrawal in mice. 132
Post-mortem interval assessment by MALDI-TOF mass spectrometry analysis in murine cadavers 129
Pharmacological activity of a Bv8 analogue modified in position 24. 128
Role of metabotropic glutamate receptor 1 in the basolateral amygdala-driven prefrontal cortical deactivation in inflammatory pain in the rat 127
Platelet-rich plasma exerts antinociceptive activity by a peripheral endocannabinoid-related mechanism 127
FAAH-Catalyzed C-C Bond Cleavage of a New Multitarget Analgesic Drug. 127
Impact of Type 1 Diabetes on Testicular Microtubule Dynamics, Sperm Physiology, and Male Reproductive Health in Rat 123
The Modulation of Pain by Metabotropic Glutamate Receptors 7 and 8 in the Dorsal Striatum. 122
Effects of URB597, an inhibitor of fatty acid amide hydrolase (FAAH), on analgesic activity of paracetamol. Neuro Endocrinol Lett. 2010;31(4):507-11. PubMed PMID: 20802454 120
Exploring the role of chloro and methyl substitutions in 2- phenylthiomethyl-benzoindole derivatives for 5-LOX enzyme inhibition 120
Piperazinyl carbamate fatty acid amide hydrolase inhibitors and transient receptor potential channel modulators as "dual-target" analgesics. 119
Altered gut microbiota and endocannabinoid system tone in vitamin D deficiency-mediated chronic pain. 118
The neuroprotective effect of cannabidiol is enhanced by resveratrol and alpha-lipoic acid in social isolation 118
Oral Cannabidiol Prevents Allodynia and Neurological Dysfunctions in a Mouse Model of Mild Traumatic Brain Injury. 117
Treatment With 2-Pentadecyl-2-Oxazoline Restores Mild Traumatic Brain Injury-Induced Sensorial and Neuropsychiatric Dysfunctions 113
Prostamide F2α receptor antagonism combined with inhibition of FAAH may block the pro-inflammatory mediators formed following selective FAAH inhibition 111
The cold case of metabotropic glutamate receptor 6: Unjust detention in the retina? 111
Protective Effects of N-Oleoylglycine in a Mouse Model of Mild Traumatic Brain Injury 108
Investigations on the 4-quinolone-3-carboxylic acid motif. 4. Identification of new potent and selective ligands for the cannabinoid type 2 receptor with diverse substitution patterns and antihyperalgesic effects in mice. 107
Spared nerve injury as a long-lasting model of neuropathic pain 105
Methods for Evaluating Sensory, Affective and Cognitive Disorders in Neuropathic Rodents 101
The activation of retinal HCA2 receptors by systemic beta-hydroxybutyrate inhibits diabetic retinal damage through reduction of endoplasmic reticulum stress and the NLRP3 inflammasome 97
Ketones and pain: unexplored role of hydroxyl carboxylic acid receptor type 2 in the pathophysiology of neuropathic pain. 97
Investigations on the 4-Quinolone-3-carboxylic acid motif. 3. Synthesis, structure-affinity relationships, and pharmacological characterization of 6-substituted 4-quinolone-3-carboxamides as highly selective cannabinoid-2 receptor ligands 96
N-palmitoyl-vanillamide (palvanil) is a non-pungent analogue of capsaicin with stronger desensitizing capability against the TRPV1 receptor and anti-hyperalgesic activity. 96
The differential modulation of pain be metabotropic glutamate receptors subtypes 7 and 8 96
Functional interaction between TRPV1 and μ-opioid receptors in the descending antinociceptive pathway activates glutamate transmission and induces analgesia 94
Ultra-micronized palmitoylethanolamide rescues the cognitive decline-associated loss of neural plasticity in the neuropathic mouse entorhinal cortex-dentate gyrus pathway. 93
Supraspinal metabotropic glutamate receptors: An endogenous substrate for alleviating chronic pain and related affective disorders 86
New Targets for Treating Chronic Pain and Inflammation. 79
null 72
Totale 14.699
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Categoria #
all - tutte 47.976
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 47.976
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022576 0 0 0 14 186 15 20 18 26 75 59 163
2022/20231.615 90 35 27 182 212 132 9 134 710 14 30 40
2023/2024640 58 29 28 37 162 53 19 85 6 6 29 128
2024/20251.765 20 16 72 88 272 204 312 141 221 165 125 129
2025/20267.440 321 416 348 298 626 3.863 537 269 295 219 144 104
2026/2027947 84 180 539 144 0 0 0 0 0 0 0 0
Totale 14.933