DE LANGE, Pieter
 Distribuzione geografica
Continente #
EU - Europa 6.883
NA - Nord America 2.891
AS - Asia 2.307
SA - Sud America 495
AF - Africa 31
OC - Oceania 3
Totale 12.610
Nazione #
RU - Federazione Russa 4.251
US - Stati Uniti d'America 2.865
SG - Singapore 905
IE - Irlanda 766
CN - Cina 509
IT - Italia 455
HK - Hong Kong 445
BR - Brasile 416
UA - Ucraina 384
DE - Germania 364
GB - Regno Unito 300
VN - Vietnam 132
FI - Finlandia 103
GR - Grecia 74
KR - Corea 70
FR - Francia 64
SE - Svezia 60
IN - India 54
TR - Turchia 51
AR - Argentina 33
JP - Giappone 26
PK - Pakistan 20
BD - Bangladesh 16
ID - Indonesia 15
AT - Austria 14
VE - Venezuela 14
BE - Belgio 12
MX - Messico 11
NL - Olanda 11
UZ - Uzbekistan 10
CA - Canada 9
EC - Ecuador 9
MA - Marocco 9
CO - Colombia 8
TH - Thailandia 8
IQ - Iraq 7
IR - Iran 7
MY - Malesia 7
ZA - Sudafrica 7
CZ - Repubblica Ceca 6
EG - Egitto 6
PH - Filippine 5
PY - Paraguay 5
KE - Kenya 4
AE - Emirati Arabi Uniti 3
BG - Bulgaria 3
CL - Cile 3
DZ - Algeria 3
KG - Kirghizistan 3
PL - Polonia 3
UY - Uruguay 3
AL - Albania 2
BH - Bahrain 2
BO - Bolivia 2
CH - Svizzera 2
DK - Danimarca 2
ES - Italia 2
IL - Israele 2
LB - Libano 2
MN - Mongolia 2
NO - Norvegia 2
PE - Perù 2
SY - Repubblica araba siriana 2
TN - Tunisia 2
AM - Armenia 1
AU - Australia 1
AZ - Azerbaigian 1
DM - Dominica 1
DO - Repubblica Dominicana 1
GT - Guatemala 1
HN - Honduras 1
HU - Ungheria 1
IS - Islanda 1
NR - Nauru 1
NZ - Nuova Zelanda 1
PR - Porto Rico 1
PS - Palestinian Territory 1
QA - Qatar 1
RO - Romania 1
SV - El Salvador 1
Totale 12.610
Città #
Moscow 1.499
Dublin 765
Jacksonville 592
Hong Kong 445
Chandler 419
Santa Clara 379
Singapore 312
Princeton 117
Grafing 110
Medford 94
Boardman 83
Bremen 82
Beijing 78
Ann Arbor 73
Roxbury 72
Ashburn 70
Hefei 69
Seoul 69
New York 65
Ho Chi Minh City 51
Wilmington 48
San Mateo 45
The Dalles 44
Naples 36
Dallas 35
Bengaluru 34
São Paulo 32
Woodbridge 30
Hanoi 28
Munich 26
Napoli 26
Los Angeles 25
Cambridge 24
Des Moines 24
Mountain View 24
Nanjing 24
Rio de Janeiro 16
Schio 16
Aversa 15
Caserta 15
Norwalk 15
Jinan 14
Brussels 12
Rome 12
Tianjin 11
Jakarta 10
Turku 10
Belo Horizonte 9
Curitiba 9
Falls Church 9
Karachi 9
Nuremberg 9
Bangkok 8
Tashkent 8
Düsseldorf 7
Frankfurt am Main 7
Guangzhou 7
Hangzhou 7
Palermo 7
Mugnano del Cardinale 6
Ninh Bình 6
Orta di Atella 6
Salvador 6
San Francisco 6
Tokyo 6
Vienna 6
Bragança Paulista 5
Brasília 5
Brooklyn 5
Caracas 5
Chennai 5
Fortaleza 5
Guarulhos 5
Houston 5
London 5
Portici 5
Porto Alegre 5
Quito 5
Redwood City 5
Rotondella 5
San Potito Sannitico 5
Atlanta 4
Auburn Hills 4
Baghdad 4
Belém 4
Brno 4
Casablanca 4
Changsha 4
Columbus 4
Contagem 4
Dhaka 4
Falkenstein 4
Groningen 4
Haiphong 4
Kuala Selangor 4
Kunming 4
Menlo Park 4
Montreal 4
Nairobi 4
Nanchang 4
Totale 6.384
Nome #
Ruolo della proteina disaccoppiante 3 (UCP3) nella sensibilità all’insulina del muscolo scheletrico 252
3,5 Diiodo-L-Thyronine (T2) Targets Different Pathways To Induce White Adipose Tissue Browning. 181
3,5 Diiodo-l-Thyronine (T-2) Promotes the Browning of White Adipose Tissue in High-Fat Diet-Induced Overweight Male Rats Housed at Thermoneutrality 162
3,5-Diiodothyronine: A Novel Thyroid Hormone Metabolite and Potent Modulator of Energy Metabolism 148
Both 3,3′,5-triiodothyronine and 3,5-diodo-L-thyronine are able to repair mitochondrial DNA damage but by different mechanisms 147
3,5-diiodo-L-thyronine influences fatty acid metabolism in higt-fat diet-fed rats through organ-specific regulation of AMP-activated proteine kinase. 144
3,5-Diiodo-L-Thyronine Affects Structural and Metabolic Features of Skeletal Muscle Mitochondria in High-Fat-Diet Fed Rats Producing a Co-adaptation to the Glycolytic Fiber Phenotype 144
3,5-Diiodo-L-Thyronine Exerts Metabolically Favorable Effects on Visceral Adipose Tissue of Rats Receiving a High-Fat Diet 144
3, 5-diiodothyronine: Biological actions and therapeutic perspectives 141
A proteomics approach to identify protein expression changes in rat liver following administration of 3,5,3′-triiodo-L-thyronine 140
3,5-diiodo-l-thyronine, by modulating mitochondrial functions, reverses hepatic fat accumulation in rats fed a high-fat diet 140
Mild Endurance Exercise during Fasting Increases Gastrocnemius Muscle and Prefrontal Cortex Thyroid Hormone Levels through Differential BHB and BCAA-Mediated BDNF-mTOR Signaling in Rats 140
3,5-diiodo-L-thyronine improves glucose tolerance in high fat fed rats 139
3,5-Diiodo-L-thyronine prevents high-fat-diet-induced insulin resistance in rat skeletal muscle through metabolic and structural adaptations 137
Ablation of uncoupling protein 3 affects interrelated factors leading to lipolysis and insulin resistance in visceral white adipose tissue 137
3,5-Diiodo-L-thyronine powerfully reduces adiposity in rats by increasing the burning of fats 136
Effect of CB1 Receptor Deficiency on Mitochondrial Quality Control Pathways in Gastrocnemius Muscle 133
Ruolo di AMPK nell’effetto della 3,5-diiodotironina (T2) sul metabolismo lipidico 133
Absence of uncoupling protein 3 at thermoneutrality influences brown adipose tissue mitochondrial functionality in mice 133
Altered Mitochondrial Quality Control in Rats with Metabolic Dysfunction-Associated Fatty Liver Disease (MAFLD) Induced by High-Fat Feeding 133
3,5-Diiodo-L-Thyronine improves mitochondrial function in nonalcoholic steatosis through the stimulation of SIRT3 mitochondrial targets 128
The impact of cannabinoid receptor 1 absence on mouse liver mitochondria homeostasis: insight into mitochondrial unfolded protein response 127
3,5-Diiodo-L-Thyronine (T2) Administration Affects Visceral Adipose Tissue Inflammatory State in Rats Receiving Long-Lasting High-Fat Diet 125
3,5-Diiodo-L-Thyronine (T2) opposes 3,5,3’-Triiodo-L- Thyronine (T3) in regulation of lipogenic signaling in rats receiving a high-fat diet. 123
The Degree Of Fatty Acid Saturation Influences The Effects Of T3 And 3,5-T2 On Insulin Sensitivity In Muscle Cell. 123
Absence of Uncoupling Protein-3 at Thermoneutrality Impacts Lipid Handling and Energy Homeostasis in Mice 121
TRC150094, a novel functional analog of iodothyronines, reduces adiposity by increasing energy expenditure and fatty acid oxidation in rats receiving a high-fat diet 120
3,5-diiodo-L-thyronine-induced proteomic changes in liver mitochondria from high fat-fed rats: Evidences from two-dimensional electrophoresis 117
Responses of skeletal muscle lipid metabolism in rat gastrocnemius to hypothyroidism and iodothyronine administration: a putative role for FAT/CD36 117
Acute administration of 3,5-diiodo-l-thyronine to hypothyroid rats affects bioenergetic parameters in rat skeletal muscle mitochondria 117
3,5diiodoLthyronine (T2) and not 3,5,3’ triiodoLthyronine (T3) reduces lipogenic signaling pathways in rats receiving a high-fat-diet. 113
High fat diet-induced insulin resistance: effects of 3,5-diiodo-L-thyronine on muscle mitochondrial proteome and function. 113
Metabolic effects of thyroid hormone derivatives 112
Dimorphic expression of uncoupling protein-3 in golden hamster harderian gland: Effects of castration and testosterone administration 112
3,5-Diiodo-L-thyronine rapidly enhances mitochondrial fatty acid oxidation rate and thermogenesis in rat skeletal muscle: AMP-activated protein kinase involvement 112
A contributing role for hepatic Sirtuins in the prevention of diet-induced adiposity by 3,5-Diiodo-L-Thyronine (T2) 112
3,5-diiodothyronine: biological actions and therapeutic perspctives 111
Thyroid-state influence on protein-expression profile of rat skeletal muscle 110
(Healthy) Ageing: Focus on Iodothyronines 110
Differential effects of 3,5-Diiodo-L-Thyronine and 3,5,3'-Triiodo-L-Thyronine on mitochondrial respiratory pathways in liver from hypothyroid rats 110
Exercise and metabolic health 107
Defining the transcriptomic and proteomic profiles of rat ageing skeletal muscle by the use of a cDNA array, 2D-and Blue native-PAGE approach 104
Uncoupling protein-3 is a molecular determinant for the regulation of resting metabolic rate by thyroid hormone 104
miR-22-3p is involved in gluconeogenic pathway modulated by 3,5-diiodo-L-thyronine (T2) 104
UCP3 Translocates Lipid Hydroperoxide and Mediates Lipid Hydroperoxide-dependent Mitochondrial Uncoupling 103
New avenues for regulation of lipid metabolism by thyroid hormones and analogs 103
Regulation of skeletal muscle mitochondrial activity by thyroid hormones: Focus on the "old" triiodothyronine and the "emerging" 3,5-diiodothyronine 102
Mild exercise rescues steroidogenesis and spermatogenesis in rats submitted to food withdrawal 102
Exercise Equals the Mobilization of Visceral versus Subcutaneous Adipose Fatty Acid Molecules in Fasted Rats Associated with the Modulation of the AMPK/ATGL/HSL Axis 101
Immunohistochemical detection of P‐glycoprotein in human tumor cells with a low degree of drug resistance 101
Pathways affected by 3,5-diiodo-l-thyronine in liver of high fat-fed rats: Evidence from two-dimensional electrophoresis, blue-native PAGE, and mass spectrometry 100
PPARs: Nuclear receptors controlled by, and controlling, nutrient handling through nuclear and cytosolic signaling 100
Tissue specific modulation of AMPK phosphorylation in high-fat diet-fed rats treated with 3,5-diiodothyronine (T2) is related to fatty acid demand 100
Adipose Tissue Remodeling in Obesity: An Overview of the Actions of Thyroid Hormones and Their Derivatives 99
Thyroid hormone affects secretory activity and uncoupling protein-3 expression in rat Harderian gland 99
Skeletal muscle mitochondrial free-fatty-acid content and membrane potential sensitivity in different thyroid states: Involvement of uncoupling protein-3 and adenine nucleotide translocase 98
Differential 3,5,3′-triiodothyronine-mediated regulation of uncoupling protein 3 transcription: Role of fatty acids 97
Combined cDNA array/RT-PCR analysis of gene expression profile in rat gastrocnemius muscle: relation to its adaptive function in energy metabolism during fasting. 96
A polymorphism in the glucocorticoid receptor gene may be associated with an increased sensitivity to glucocorticoids in vivo 96
UCP3 activation: Mutual relationship between superoxides and polyunsaturated fatty acids 96
Rapid effect of 3,5-diiodo-L-thyronine on mitochondrial fatty acid metabolism in skeletal muscle 96
Exercise, fasting, and mimetics: Toward beneficial combinations? 96
Lack of association between five polymorphisms in the human glucocorticoid receptor gene and glucocorticoid resistance 95
T3 coordinately affects expression of genes related to uncoupling protein 3 (UCP3) activity and lipid handling in rat gastrocnemius muscle. 95
Thyroid: biological actions of 'nonclassical' thyroid hormones 93
Mammalian mitochondrial proteome and its functions: Current investigative techniques and future perspectives on ageing and diabetes 93
Ruolo dell’AMPK nella risposta organo specifica alla somministrazione di 3,5-diiodo-L-tironina (T2) a ratti alimentati con dieta iperlipidica 93
Fasting, lipid metabolism, and triiodothyronine in rat gastrocnemius muscle: interrelated roles of uncoupling protein 3, mitochondrial thioesterase, and coenzyme Q 92
Temporal relationship between organ responses to 3,5-diiodo-L-thyronine in high-fat diet-fed rats role of AMPK 92
Rapid modulation of interscapular brown adipose tissue mitochondrial activity by ketosis induced by 1,3-butanediol administration to rats 91
Fuel economy in food-deprived skeletal muscle: signaling pathways and regulatory mechanisms 91
Expression in hematological malignancies of a glucocorticoid receptor splice variant that augments glucocorticoid receptor-mediated effects in transfected cells 90
Uncoupling proteins: A complex journey to function discovery 90
Sequential changes in the signal transduction responses of skeletal muscle following food deprivation 90
Effetti non genomici della 3,5,3’-L-Triiodotironina: induzione delle vie di segnalazione mediate da AMPK/ACC e AKT/PKB nel muscolo gastrocnemio di ratto 90
Metabolic effects of the iodothyronine functional analogue TRC150094 on the liver and skeletal muscle of high-fat diet fed overweight rats: An integrated proteomic study 90
Thyroid-hormone effects on putative biochemical pathways involved in UCP3 activation in rat skeletal muscle mitochondria 89
Nonthyrotoxic Prevention of Diet-Induced Insulin Resistance by 3,5-Diiodo-L-Thyronine in Rats 89
Both 3,5-Diiodo-L-Thyronine and 3,5,3'-Triiodo-L-Thyronine Prevent Short-term Hepatic Lipid Accumulation via Distinct Mechanisms in Rats Being Fed a High-Fat Diet 88
Metabolic action of thyroid hormones: Insights from functional and proteomic studies 87
Antisense chalcone synthase genes in petunia: Visualization of variable transgene expression 87
Rapid activation by 3,5,3′-L-triiodothyronine of adenosine 5′-monophosphate-activated protein kinase/acetyl-coenzyme A carboxylase and Akt/protein kinase B signaling pathways: Relation to changes in fuel metabolism and myosin heavy-chain protein content in rat gastrocnemius muscle in vivo 87
Role of AMPK in the organ-specific responses to 3,5-diiodo-L-thyronine in high-fat diet-fed rats 87
Uncoupling protein 3 expression levels influence insulin sensitivity, fatty acid oxidation, and related signaling pathways 87
Fenofibrate activates the biochemical pathways and the de novo expression of genes related to lipid handling and uncoupling protein-3 functions in liver of normal rats 86
Skeletal muscle mitochondrial free-fatty-acid content and membrane potential sensitivity in different thyroid states: involvement of uncoupling protein-3 and adenine nucleotide translocase 85
Interperson variability but intraperson stability of baseline plasma cortisol concentrations, and its relation to feedback sensitivity of the hypothalamo-pituitary-adrenal axis to a low dose of dexamethasone in elderly individuals 85
Inefficienza mitocondriale mediata da UCP3: induzione da parte dell’acido arachidonico e coinvolgimento della perossidazione lipidica 85
The saturation degree of fatty acids and their derived acylcarnitines determines the direct effect of metabolically active thyroid hormones on insulin sensitivity in skeletal muscle cells 85
Adaptive Thermogenesis Driving Catch-Up Fat Is Associated With Increased Muscle Type 3 and Decreased Hepatic Type 1 Iodothyronine Deiodinase Activities: A Functional and Proteomic Study 85
Interrelated influence of superoxides and free fatty acids over mitochondrial uncoupling in skeletal muscle 84
Human adrenocorticotropin-secreting pituitary adenomas show frequent loss of heterozygosity at the glucocorticoid receptor gene locus 84
Influence of 3,5-diiodo-L-thyronine on skeletal muscle lipid metabolism 83
Comparative effects of 3,5-diiodo-L-thyronine and 3,5,3’-triiodo-L-thyronine on mitochondrial damage and cGAS/STING-driven inflammation in liver of hypothyroid rats 82
Effect of 3,5-Diiodo-L-Thyronine on high-fat diet-induced visceral adiposity in the rat 82
The Thyroid Hormone-target Gene Rhes a Novel Crossroad for Neurological and Psychiatric Disorders: New Insights from Animal Models 82
Studies of complex biological systems with applications to molecular medicine: The need to integrate transcriptomic and proteomic approaches 82
Peroxisome proliferator-activated receptor delta: A conserved director of lipid homeostasis through regulation of the oxidative capacity of muscle 81
Organ-specific response to high-fat diet and 3,5-diiodothyronine (T2) treatment; a possible involvement of the AMP-activated protein kinase (AMPK) 81
The thyroid hormone metabolite 3,5-diiodo-l-thyronine prevents hepatic fat accumulation and systemic insulin resistance through direct activation of sirtuin 1 (SIRT1) 81
Totale 10.820
Categoria #
all - tutte 44.056
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 44.056


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021444 0 0 0 0 0 6 117 96 16 108 87 14
2021/2022768 53 3 6 9 229 135 8 24 25 19 53 204
2022/20231.537 154 66 11 127 184 108 10 79 724 14 29 31
2023/2024594 50 29 13 50 188 66 6 18 5 5 41 123
2024/20251.817 10 32 26 23 290 199 270 147 287 262 158 113
2025/20265.869 205 248 346 405 600 4.065 0 0 0 0 0 0
Totale 12.770