IRIS
DE LANGE, Pieter
 Distribuzione geografica
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Continente #
EU - Europa 2.430
NA - Nord America 2.198
AS - Asia 316
AF - Africa 6
SA - Sud America 3
OC - Oceania 1
Totale 4.954
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Nazione #
US - Stati Uniti d'America 2.196
IE - Irlanda 764
UA - Ucraina 377
IT - Italia 374
DE - Germania 319
GB - Regno Unito 288
SG - Singapore 124
CN - Cina 122
FI - Finlandia 91
GR - Grecia 74
FR - Francia 61
SE - Svezia 57
TR - Turchia 43
BE - Belgio 12
PK - Pakistan 9
EG - Egitto 5
NL - Olanda 5
CZ - Repubblica Ceca 4
IR - Iran 4
JP - Giappone 4
BD - Bangladesh 2
HK - Hong Kong 2
PH - Filippine 2
TH - Thailandia 2
AR - Argentina 1
AT - Austria 1
BR - Brasile 1
CH - Svizzera 1
CL - Cile 1
DK - Danimarca 1
HN - Honduras 1
IN - India 1
KR - Corea 1
MA - Marocco 1
MX - Messico 1
NZ - Nuova Zelanda 1
RO - Romania 1
Totale 4.954
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Città #
Dublin 764
Jacksonville 592
Chandler 419
Princeton 117
Grafing 110
Medford 94
Boardman 82
Bremen 82
Ann Arbor 73
Singapore 73
Roxbury 72
New York 58
Wilmington 48
Beijing 45
San Mateo 45
Woodbridge 30
Napoli 26
Cambridge 24
Des Moines 24
Mountain View 24
Nanjing 23
Naples 16
Schio 16
Caserta 15
Norwalk 15
Jinan 13
Brussels 12
Falls Church 9
Ashburn 7
Düsseldorf 7
Karachi 7
Palermo 7
Mugnano del Cardinale 6
Hangzhou 5
Houston 5
Los Angeles 5
Portici 5
Redwood City 5
Rotondella 5
Auburn Hills 4
Brno 4
Groningen 4
Kunming 4
Menlo Park 4
Nanchang 4
San Marco Evangelista 4
San Martino Sannita 4
Atlanta 3
Aversa 3
Capodrise 3
Changchun 3
Cicciano 3
Mariglianella 3
Milan 3
Rome 3
Shenyang 3
Taiyuan 3
Tianjin 3
Tokyo 3
Torre Del Greco 3
Bangkok 2
Castellarano 2
Cava De' Tirreni 2
Changsha 2
Civitanova Marche 2
Clifton 2
Damietta 2
Duino-Aurisina 2
Fairfield 2
Fiumicino 2
Hong Kong 2
Lanzhou 2
London 2
Maddaloni 2
Marano di Napoli 2
Marseille 2
Mashhad 2
Ningbo 2
Orta di Atella 2
Pomigliano D'arco 2
Putignano 2
San Felice A Cancello 2
San Giorgio Del Sannio 2
San Giuliano Milanese 2
San Giuseppe Vesuviano 2
San Martino Valle Caudina 2
San Pablo City 2
San Remo 2
Sesto San Giovanni 2
Tappahannock 2
Teano 2
Tuenno 2
Venice 2
Villaricca 2
Amorosi 1
Amsterdam 1
Andover 1
Angri 1
Auckland 1
Avellino 1
Totale 3.130
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Nome #
Ruolo della proteina disaccoppiante 3 (UCP3) nella sensibilità all’insulina del muscolo scheletrico 199
3,5 Diiodo-L-Thyronine (T2) Targets Different Pathways To Induce White Adipose Tissue Browning. 83
Ruolo di AMPK nell’effetto della 3,5-diiodotironina (T2) sul metabolismo lipidico 80
TRC150094, a novel functional analog of iodothyronines, reduces adiposity by increasing energy expenditure and fatty acid oxidation in rats receiving a high-fat diet 75
3,5 Diiodo-l-Thyronine (T-2) Promotes the Browning of White Adipose Tissue in High-Fat Diet-Induced Overweight Male Rats Housed at Thermoneutrality 72
Responses of skeletal muscle lipid metabolism in rat gastrocnemius to hypothyroidism and iodothyronine administration: a putative role for FAT/CD36 69
3,5-diiodo-L-thyronine influences fatty acid metabolism in higt-fat diet-fed rats through organ-specific regulation of AMP-activated proteine kinase. 68
3,5-diiodo-l-thyronine, by modulating mitochondrial functions, reverses hepatic fat accumulation in rats fed a high-fat diet 65
3,5-Diiodo-L-Thyronine Exerts Metabolically Favorable Effects on Visceral Adipose Tissue of Rats Receiving a High-Fat Diet 61
Metabolic effects of thyroid hormone derivatives 59
Both 3,3′,5-triiodothyronine and 3,5-diodo-L-thyronine are able to repair mitochondrial DNA damage but by different mechanisms 59
Defining the transcriptomic and proteomic profiles of rat ageing skeletal muscle by the use of a cDNA array, 2D-and Blue native-PAGE approach 58
3,5-Diiodothyronine: A Novel Thyroid Hormone Metabolite and Potent Modulator of Energy Metabolism 57
3,5-diiodo-L-thyronine improves glucose tolerance in high fat fed rats 56
3,5-Diiodo-L-Thyronine Affects Structural and Metabolic Features of Skeletal Muscle Mitochondria in High-Fat-Diet Fed Rats Producing a Co-adaptation to the Glycolytic Fiber Phenotype 56
A proteomics approach to identify protein expression changes in rat liver following administration of 3,5,3′-triiodo-L-thyronine 55
Regulation of skeletal muscle mitochondrial activity by thyroid hormones: Focus on the "old" triiodothyronine and the "emerging" 3,5-diiodothyronine 54
3, 5-diiodothyronine: Biological actions and therapeutic perspectives 54
3,5-Diiodo-L-thyronine powerfully reduces adiposity in rats by increasing the burning of fats 53
Tissue specific modulation of AMPK phosphorylation in high-fat diet-fed rats treated with 3,5-diiodothyronine (T2) is related to fatty acid demand 52
Thyroid-state influence on protein-expression profile of rat skeletal muscle 51
Pathways affected by 3,5-diiodo-l-thyronine in liver of high fat-fed rats: Evidence from two-dimensional electrophoresis, blue-native PAGE, and mass spectrometry 51
PPARs: Nuclear receptors controlled by, and controlling, nutrient handling through nuclear and cytosolic signaling 51
UCP3 Translocates Lipid Hydroperoxide and Mediates Lipid Hydroperoxide-dependent Mitochondrial Uncoupling 50
Dimorphic expression of uncoupling protein-3 in golden hamster harderian gland: Effects of castration and testosterone administration 50
3,5-diiodo-L-thyronine-induced proteomic changes in liver mitochondria from high fat-fed rats: Evidences from two-dimensional electrophoresis 50
Differential 3,5,3′-triiodothyronine-mediated regulation of uncoupling protein 3 transcription: Role of fatty acids 49
3,5-Diiodo-L-Thyronine improves mitochondrial function in nonalcoholic steatosis through the stimulation of SIRT3 mitochondrial targets 49
New avenues for regulation of lipid metabolism by thyroid hormones and analogs 48
3,5-diiodothyronine: biological actions and therapeutic perspctives 48
Uncoupling protein-3 is a molecular determinant for the regulation of resting metabolic rate by thyroid hormone 47
T3 coordinately affects expression of genes related to uncoupling protein 3 (UCP3) activity and lipid handling in rat gastrocnemius muscle. 47
Metabolic effects of the iodothyronine functional analogue TRC150094 on the liver and skeletal muscle of high-fat diet fed overweight rats: An integrated proteomic study 47
Immunohistochemical detection of P‐glycoprotein in human tumor cells with a low degree of drug resistance 46
Lack of association between five polymorphisms in the human glucocorticoid receptor gene and glucocorticoid resistance 46
3,5-Diiodo-L-thyronine prevents high-fat-diet-induced insulin resistance in rat skeletal muscle through metabolic and structural adaptations 46
3,5-Diiodo-L-Thyronine (T2) opposes 3,5,3’-Triiodo-L- Thyronine (T3) in regulation of lipogenic signaling in rats receiving a high-fat diet. 46
Exercise and metabolic health 46
Thyroid hormone affects secretory activity and uncoupling protein-3 expression in rat Harderian gland 45
Absence of Uncoupling Protein-3 at Thermoneutrality Impacts Lipid Handling and Energy Homeostasis in Mice 45
Absence of uncoupling protein 3 at thermoneutrality influences brown adipose tissue mitochondrial functionality in mice 45
Uncoupling proteins: A complex journey to function discovery 44
Thyroid-hormone effects on putative biochemical pathways involved in UCP3 activation in rat skeletal muscle mitochondria 44
Temporal relationship between organ responses to 3,5-diiodo-L-thyronine in high-fat diet-fed rats role of AMPK 44
Ablation of uncoupling protein 3 affects interrelated factors leading to lipolysis and insulin resistance in visceral white adipose tissue 44
A polymorphism in the glucocorticoid receptor gene may be associated with an increased sensitivity to glucocorticoids in vivo 43
The Degree Of Fatty Acid Saturation Influences The Effects Of T3 And 3,5-T2 On Insulin Sensitivity In Muscle Cell. 43
Skeletal muscle mitochondrial free-fatty-acid content and membrane potential sensitivity in different thyroid states: Involvement of uncoupling protein-3 and adenine nucleotide translocase 42
Fenofibrate activates the biochemical pathways and the de novo expression of genes related to lipid handling and uncoupling protein-3 functions in liver of normal rats 42
Inefficienza mitocondriale mediata da UCP3: induzione da parte dell’acido arachidonico e coinvolgimento della perossidazione lipidica 42
Exercise, fasting, and mimetics: Toward beneficial combinations? 42
Mild Endurance Exercise during Fasting Increases Gastrocnemius Muscle and Prefrontal Cortex Thyroid Hormone Levels through Differential BHB and BCAA-Mediated BDNF-mTOR Signaling in Rats 42
Control of energy metabolism by iodothyronines 41
3,5-Diiodo-L-thyronine rapidly enhances mitochondrial fatty acid oxidation rate and thermogenesis in rat skeletal muscle: AMP-activated protein kinase involvement 41
Ruolo dell’AMPK nella risposta organo specifica alla somministrazione di 3,5-diiodo-L-tironina (T2) a ratti alimentati con dieta iperlipidica 41
3,5-Diiodo-L-Thyronine (T2) Administration Affects Visceral Adipose Tissue Inflammatory State in Rats Receiving Long-Lasting High-Fat Diet 41
Fasting, lipid metabolism, and triiodothyronine in rat gastrocnemius muscle: interrelated roles of uncoupling protein 3, mitochondrial thioesterase, and coenzyme Q 40
Antisense chalcone synthase genes in petunia: Visualization of variable transgene expression 40
A contributing role for hepatic Sirtuins in the prevention of diet-induced adiposity by 3,5-Diiodo-L-Thyronine (T2) 40
Expression in hematological malignancies of a glucocorticoid receptor splice variant that augments glucocorticoid receptor-mediated effects in transfected cells 39
Interrelated influence of superoxides and free fatty acids over mitochondrial uncoupling in skeletal muscle 39
Effetti non genomici della 3,5,3’-L-Triiodotironina: induzione delle vie di segnalazione mediate da AMPK/ACC e AKT/PKB nel muscolo gastrocnemio di ratto 39
(Healthy) Ageing: Focus on Iodothyronines 39
The saturation degree of fatty acids and their derived acylcarnitines determines the direct effect of metabolically active thyroid hormones on insulin sensitivity in skeletal muscle cells 39
Metabolic action of thyroid hormones: Insights from functional and proteomic studies 38
Influence of 3,5-diiodo-L-thyronine on skeletal muscle lipid metabolism 38
3,5diiodoLthyronine (T2) and not 3,5,3’ triiodoLthyronine (T3) reduces lipogenic signaling pathways in rats receiving a high-fat-diet. 38
miR-22-3p is involved in gluconeogenic pathway modulated by 3,5-diiodo-L-thyronine (T2) 38
Altered Mitochondrial Quality Control in Rats with Metabolic Dysfunction-Associated Fatty Liver Disease (MAFLD) Induced by High-Fat Feeding 38
Combined cDNA array/RT-PCR analysis of gene expression profile in rat gastrocnemius muscle: relation to its adaptive function in energy metabolism during fasting. 37
Thyroid: biological actions of 'nonclassical' thyroid hormones 37
Age-related changes in renal and hepatic cellular mechanisms associated with variations in rat serum thyroid hormone levels 36
The Thyroid Hormone-target Gene Rhes a Novel Crossroad for Neurological and Psychiatric Disorders: New Insights from Animal Models 36
Nonthyrotoxic Prevention of Diet-Induced Insulin Resistance by 3,5-Diiodo-L-Thyronine in Rats 36
Differential effects of 3,5-Diiodo-L-Thyronine and 3,5,3'-Triiodo-L-Thyronine on mitochondrial respiratory pathways in liver from hypothyroid rats 36
Acute administration of 3,5-diiodo-l-thyronine to hypothyroid rats affects bioenergetic parameters in rat skeletal muscle mitochondria 36
Fuel economy in food-deprived skeletal muscle: signaling pathways and regulatory mechanisms 35
Non genomic effects of 3,5,3-L-triiodothyronina through AMPK/ACC and AKT/PKB signaling: relation to changes in fuel metabolism and myosin heavy chain protein content in rat gastrocnemius muscle in vivo 35
Rapid activation by 3,5,3’-L-triiodothyronine of AMPK/ACC and Akt/PKB signaling pathways in rat gastrocnemius muscle in vivo 35
Role of AMPK in the organ-specific responses to 3,5-diiodo-L-thyronine in high-fat diet-fed rats 35
Rapid activation by 3,5,3′-L-triiodothyronine of adenosine 5′-monophosphate-activated protein kinase/acetyl-coenzyme A carboxylase and Akt/protein kinase B signaling pathways: Relation to changes in fuel metabolism and myosin heavy-chain protein content in rat gastrocnemius muscle in vivo 34
Human adrenocorticotropin-secreting pituitary adenomas show frequent loss of heterozygosity at the glucocorticoid receptor gene locus 34
Prevention of diet-induced insulin resistance by 3,5-Diiodo-L-Thyronine in rats involves SIRT1 34
High fat diet-induced insulin resistance: effects of 3,5-diiodo-L-thyronine on muscle mitochondrial proteome and function. 34
Thyroid Hormone and Metabolites: Central Versus Peripheral Effects 34
Sequential changes in the signal transduction responses of skeletal muscle following food deprivation 33
Effect of 3,5-Diiodo-L-Thyronine on high-fat diet-induced visceral adiposity in the rat 33
Uncoupling protein 3 expression levels influence insulin sensitivity, fatty acid oxidation, and related signaling pathways 33
Studies of complex biological systems with applications to molecular medicine: The need to integrate transcriptomic and proteomic approaches 33
Mammalian mitochondrial proteome and its functions: Current investigative techniques and future perspectives on ageing and diabetes 32
Five patients with biochemical and/or clinical generalized glucocorticoid resistance without alterations in the glucocorticoid receptor gene 32
Both 3,5-Diiodo-L-Thyronine and 3,5,3'-Triiodo-L-Thyronine Prevent Short-term Hepatic Lipid Accumulation via Distinct Mechanisms in Rats Being Fed a High-Fat Diet 32
Decreased ligand affinity rather than glucocorticoid receptor down-regulation in patients with endogenous Cushing's syndrome 31
Peroxisome proliferator-activated receptor delta: A conserved director of lipid homeostasis through regulation of the oxidative capacity of muscle 31
Non-nuclear actions of thyroid hormones: the case of T2 31
UCP3 activation: Mutual relationship between superoxides and polyunsaturated fatty acids 31
Organ-specific response to high-fat diet and 3,5-diiodothyronine (T2) treatment; a possible involvement of the AMP-activated protein kinase (AMPK) 31
Uncoupling protein 3 (UCP3) participates in the translocation of lipid hydroperoxides (LOOH) across the mitochondrial inner membrane and in the LOOH-dependent mitochondrial uncoupling 31
USE OF GENETIC-ENGINEERING TO IMPROVE YIELDS IN CELL-CULTURES, EG (ANTI)SENSE DNA TECHNOLOGY 30
The thyroid hormone metabolite 3,5-diiodo-l-thyronine prevents hepatic fat accumulation and systemic insulin resistance through direct activation of sirtuin 1 (SIRT1) 30
Totale 4.567
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Categoria #
all - tutte 20.930
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 20.930
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020695 129 107 16 25 132 6 120 31 48 27 42 12
2020/2021788 81 5 98 31 129 6 117 96 16 108 87 14
2021/2022768 53 3 6 9 229 135 8 24 25 19 53 204
2022/20231.537 154 66 11 127 184 108 10 79 724 14 29 31
2023/2024594 50 29 13 50 188 66 6 18 5 5 41 123
2024/20258 8 0 0 0 0 0 0 0 0 0 0 0
Totale 5.092