This article has been corrected: In Figure 3B, the caspase 3 blot in the SW-48 column is an accidental duplicate of the caspase 3 blot in the HC-15 column. The corrected Figure 3B, obtained using the original data, is shown below. The authors declare that these corrections do not change the results or conclusions of this paper. Original article: Oncotarget. 2017; 8:68305–68316. https://doi.org/10.18632/oncotarget.20054 Figure 3: Effects of regorafenib in combination with silybin on induction of apoptosis in SW48, SW48-CR, HCT15 and SW480 colon cancer cells. (A) Apoptosis was evaluated with Annexin-V-FITC staining and 7-Amino-Actinomycin D (7-AAD) detection assays using flow cytometry in SW48, SW48-CR, HCT15 and SW480 cancer cells after 24 hours of incubation with silybin (90 μM) or regorafenib (2 μM) and their combination. Histogram of data expressed as percentage of apoptotic cells.*p < 0.05 compared to single treatment. (B) Colon cancer cells were treated with silybin (90 μM) or regorafenib (2 μM) and their combination for 24 hours. Expression of PARP, caspase 3 and 9 were evaluated by immunoblotting as described in Materials and Methods. α-Tubulin was used as the loading control.

Correction: Regorafenib in combination with silybin as a novel potential strategy for the treatment of metastatic colorectal cancer

Martinelli, Erika;Napolitano, Stefania;Morgillo, Floriana;Tuccillo, Concetta;Federico, Alessandro;Dallio, Marcello;Loguercio, Carmelina;Gravina, Antonietta Gerarda;Palma, Raffaele De;Ciardiello, Fortunato;Troiani, Teresa
2025

Abstract

This article has been corrected: In Figure 3B, the caspase 3 blot in the SW-48 column is an accidental duplicate of the caspase 3 blot in the HC-15 column. The corrected Figure 3B, obtained using the original data, is shown below. The authors declare that these corrections do not change the results or conclusions of this paper. Original article: Oncotarget. 2017; 8:68305–68316. https://doi.org/10.18632/oncotarget.20054 Figure 3: Effects of regorafenib in combination with silybin on induction of apoptosis in SW48, SW48-CR, HCT15 and SW480 colon cancer cells. (A) Apoptosis was evaluated with Annexin-V-FITC staining and 7-Amino-Actinomycin D (7-AAD) detection assays using flow cytometry in SW48, SW48-CR, HCT15 and SW480 cancer cells after 24 hours of incubation with silybin (90 μM) or regorafenib (2 μM) and their combination. Histogram of data expressed as percentage of apoptotic cells.*p < 0.05 compared to single treatment. (B) Colon cancer cells were treated with silybin (90 μM) or regorafenib (2 μM) and their combination for 24 hours. Expression of PARP, caspase 3 and 9 were evaluated by immunoblotting as described in Materials and Methods. α-Tubulin was used as the loading control.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11591/585473
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