Multicentric basal cell carcinoma of the penis and scrotum: a rare case report

Genital BCC (Basal Cell Carcinoma) tends to present at a more advanced stage due to delayed diagnosis, often exacerbated by patient embarrassment, misdiagnosis, or lack of symptoms. We present an extremely rare case of multicentric BCC involving the penis and scrotum in a 66-year-old Caucasian male, presented with progressive and recurrent genital skin lesions causing discomfort and an ulcerated lesion of the glans. Surgical treatment included en-bloc wide local excision of the skin with glansectomy and reconstruction using Singapore and Keystone flaps, along with skin grafting. Histopathological analysis revealed infiltrative BCC with vascular and perineural invasion and extension into the corpus spongiosum of glans. The residual stump preserved spontaneous erectile function. Follow-up is ongoing every 3 months. This case underscores the diagnostic and therapeutic challenges of genital BCC, particularly when presenting in advanced, multicentric forms.