Background and Aim: Current literature regarding insulin pump-associated adverse events including pump malfunction, infusion set/site issues is discussed. We evaluated metabolic and non–metabolic adverse events in a large cohort of children and adolescents with type 1 diabetes (T1D), using insulin pump therapy. Methods: Data have been collected on patients younger than 19 years, starting insulin pump therapy before December 31 2013. For each patient age, disease duration, date of insulin pump therapy initiation, insulin pump model, breakdown/malfunction/pump replacement yes/no and reason, catheter/infusion set failures have been considered prospectively for the calendar year 2014. Results: Data have been returned by 20 pediatric Centers belonging to the Italian Diabetes Study Group about 916 T1D children and adolescents using insulin pump. During 2014, the most frequent infusion set and site problems were bubbles (38.2%), kinking (13%), leakage (10.3%), tunneling (10.2%), blockage (8.8%), bleeding (11%), lipohypertrophy (7.1%), infection (1.4%). Pump device has been replaced in 19.2% of patients: 82% for pump breakdown/malfunctions and 18% for ‘physiologic’ replacement after warranty. HbA1C mean value was 7.6% for the whole population. No relationship between pump replacement and HbA1C value was found. Only 1 DKA has been recorded due to pump failure. No severe hypoglycemia has been recorded due to pump or infusion set malfunction. Conclusions: Despite frequent infusion set problems, pump breakdown/malfunction and consequent replacement and metabolic adverse events in a large cohort of pediatric Italian patients with T1D are not as frequent as previously reported. Continuous educational programs are necessary for pump therapy management.

PUMP FAILURE AND MALFUNCTIONS IN CHILDREN AND ADOLESCENTS WITH TYPE 1 DIABETES IN INSULIN PUMP THERAPY: AN ITALIAN PROSPECTIVE STUDYin 9th International Conference on Advanced Technologies & Treatment of Diabetes (ATTD) Barcellona 2016

Iafusco D.
Conceptualization
;
2016

Abstract

Background and Aim: Current literature regarding insulin pump-associated adverse events including pump malfunction, infusion set/site issues is discussed. We evaluated metabolic and non–metabolic adverse events in a large cohort of children and adolescents with type 1 diabetes (T1D), using insulin pump therapy. Methods: Data have been collected on patients younger than 19 years, starting insulin pump therapy before December 31 2013. For each patient age, disease duration, date of insulin pump therapy initiation, insulin pump model, breakdown/malfunction/pump replacement yes/no and reason, catheter/infusion set failures have been considered prospectively for the calendar year 2014. Results: Data have been returned by 20 pediatric Centers belonging to the Italian Diabetes Study Group about 916 T1D children and adolescents using insulin pump. During 2014, the most frequent infusion set and site problems were bubbles (38.2%), kinking (13%), leakage (10.3%), tunneling (10.2%), blockage (8.8%), bleeding (11%), lipohypertrophy (7.1%), infection (1.4%). Pump device has been replaced in 19.2% of patients: 82% for pump breakdown/malfunctions and 18% for ‘physiologic’ replacement after warranty. HbA1C mean value was 7.6% for the whole population. No relationship between pump replacement and HbA1C value was found. Only 1 DKA has been recorded due to pump failure. No severe hypoglycemia has been recorded due to pump or infusion set malfunction. Conclusions: Despite frequent infusion set problems, pump breakdown/malfunction and consequent replacement and metabolic adverse events in a large cohort of pediatric Italian patients with T1D are not as frequent as previously reported. Continuous educational programs are necessary for pump therapy management.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11591/436065
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