Bisphenol A (BPA) is one of the highest volume chemicals produced worldwide. It has recognized activity as an endocrine disrupting chemical and has suspected roles as a neurological and reproductive toxicant. It interferes in steroid signaling, induces oxidative stress, and affects gene expression epigenetically. Gestational, perinatal and neonatal exposures to BPA affect developmental processes, including brain development and gametogenesis, with consequences on brain functions, behavior, and fertility.
Neuro-toxic and reproductive effects of BPA.
Chianese, Rosanna;Fasano, Silvia;Pierantoni, Riccardo;
2019
Abstract
Bisphenol A (BPA) is one of the highest volume chemicals produced worldwide. It has recognized activity as an endocrine disrupting chemical and has suspected roles as a neurological and reproductive toxicant. It interferes in steroid signaling, induces oxidative stress, and affects gene expression epigenetically. Gestational, perinatal and neonatal exposures to BPA affect developmental processes, including brain development and gametogenesis, with consequences on brain functions, behavior, and fertility.File in questo prodotto:
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