Objective: Many observational studies and some clinical trials suggested a role of vitamin D counteracting bone and muscle loss in aging. Low serum levels of 25- hydroxyvitamin D (25OHD) seem to be associated with reduced muscle strength and physical performance. The aim of our study was to compare physical performance and muscle strength in subjects with different serum levels of vitamin D. Materials and methods:We compared 40 patients with vitamin D deficiency (25 OHD <30 ng/ml) to 37 subjects with normal serum levels of 25 OHD (≥30 ng/ml). The muscle strength and muscle performance were, respectively, assessed with the Jamar handheld dynamometer and the Short Physical Performance Battery (SPPB). Results: Shown in the table. Parameters Vitamin D deficiency subjects Normal subjects p-value (n=40) (n=37) Age (year) 66.9±7.27 67.54±8.29 NS Body Mass Index (BMI) (kg/m2) 25.37±3.59 25.72±3.25 NS HGS (kg) 12.81±5.10 15.70±6.89 0.038 Gait speed <1 m/s: 25/40 (62.5 %) <1 m/s: 20/37 (54.1 %) NS >1 m/s: 15/40 (37.5 %) >1 M/s: 17/37 (45.9 %) SPPB score <8: 17/40: (42.5 %) <8: 10/37 (27 %) NS >8: 23/40 (57.5 %) >8: 20/37 (73 %) Conclusion: Subjects with hypovitaminosis D resulted to have a reduction in SPPB score, gait speed, and handgrip strength, but only for the latter there is a statistical significant between-group difference. References: Tomlinson PB et al., J Sci Med Sport. 2014 Aug 11 pii: S1440- 2440(14)00163-7.
|Titolo:||P515 MUSCLE STRENGTH AND PHYSICAL PERFORMANCE IN PATIENTS WITH VITAMIN D DEFICIENCY|
|Data di pubblicazione:||2015|
|Appare nelle tipologie:||1.5 Abstract in rivista|