The Authors report two cases of sudden deaths in young women by giant cell myocarditis (GCM). The autopsies showed areas of myocardial necrosis at the left ventricle associated only in one case with thrombosis of a coronary artery. Microscopically, at the above areas of myocardial necrosis, myocyte degeneration and necrosis were adjacent to an interstitial inflammatory infiltrate made by several giant cells. The anatomically findings were both the result of a myocarditis damage as supported by granulomatous reaction and non-occlusive coronary thrombosis. based on the two cases illustrated in this article and on the review of the literature the Authors suggest a complete post-mortem exam focusing on the criteria for the diagnosis of giant cell myocarditis (GCM).

Miocardite a cellule giganti e morte improvvisa

CAMPOBASSO, Carlo Pietro;
2002

Abstract

The Authors report two cases of sudden deaths in young women by giant cell myocarditis (GCM). The autopsies showed areas of myocardial necrosis at the left ventricle associated only in one case with thrombosis of a coronary artery. Microscopically, at the above areas of myocardial necrosis, myocyte degeneration and necrosis were adjacent to an interstitial inflammatory infiltrate made by several giant cells. The anatomically findings were both the result of a myocarditis damage as supported by granulomatous reaction and non-occlusive coronary thrombosis. based on the two cases illustrated in this article and on the review of the literature the Authors suggest a complete post-mortem exam focusing on the criteria for the diagnosis of giant cell myocarditis (GCM).
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11591/369074
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