Large local reactions (LLRs) caused by insect stings are frequent in adults [1] and are usually induced by an IgE-dependent late-phase reaction [2]. A number of cases of acquired cold urticaria/anaphylaxis after LLRs have been reported, whereas cases of delayed anaphylaxis caused by insect stings have proved to be merely anecdotal [3-5]. Although vibratory angioedema is a rare disorder, cases resulting from mast-cell degranulation have been reported [6,7]. We evaluated serum tryptase level (as a marker of mast cell degranulation [8]) and vibration sensitivity in a patient who experienced severe anaphylaxis 18 hours after a wasp sting.

Venom-dependent vibration-induced anaphylaxis: A new hazard following large local reactions from hymenoptera stings

ASTARITA, Corrado;
2014

Abstract

Large local reactions (LLRs) caused by insect stings are frequent in adults [1] and are usually induced by an IgE-dependent late-phase reaction [2]. A number of cases of acquired cold urticaria/anaphylaxis after LLRs have been reported, whereas cases of delayed anaphylaxis caused by insect stings have proved to be merely anecdotal [3-5]. Although vibratory angioedema is a rare disorder, cases resulting from mast-cell degranulation have been reported [6,7]. We evaluated serum tryptase level (as a marker of mast cell degranulation [8]) and vibration sensitivity in a patient who experienced severe anaphylaxis 18 hours after a wasp sting.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11591/343123
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