Malignant peripheral nerve sheath tumors (MPNSTs) are sarcomas originating from the cells constituting the nerve sheaths such as Schwann cells, perineural cells or fibroblasts. They represent approximately 5-10% of all soft tissue sarcomas. They have been rarely observed in the lung. We describe a rare case of primary lung MPNST in an elderly male patient, in which surgical approach has obtained a good control of the disease. Immuno-histochemical and molecular analyses have been required on the surgical specimen due to inadequate possibility of recognition through morphology alone.
Primary intrapulmonary malignant peripheral nerve sheath tumor mimicking lung cancer
FRANCO, Renato;
2013
Abstract
Malignant peripheral nerve sheath tumors (MPNSTs) are sarcomas originating from the cells constituting the nerve sheaths such as Schwann cells, perineural cells or fibroblasts. They represent approximately 5-10% of all soft tissue sarcomas. They have been rarely observed in the lung. We describe a rare case of primary lung MPNST in an elderly male patient, in which surgical approach has obtained a good control of the disease. Immuno-histochemical and molecular analyses have been required on the surgical specimen due to inadequate possibility of recognition through morphology alone.File in questo prodotto:
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