Resistance to tyrosine kinase inhibitors (TKI) of EGF receptor (EGFR) is often related to activation of other signaling pathways and evolution through a mesenchymal phenotype.
SMO Gene Amplification and Activation of the Hedgehog Pathway as Novel Mechanisms of Resistance to Anti-Epidermal Growth Factor Receptor Drugs in Human Lung Cancer
Della Corte, Carminia Maria;VICIDOMINI, Giovanni;ACCARDO, Marina;FIORELLI, Alfonso;MARTINELLI, Erika;TROIANI, Teresa;SANTINI, Mario;CIARDIELLO, Fortunato;MORGILLO, Floriana
2015
Abstract
Resistance to tyrosine kinase inhibitors (TKI) of EGF receptor (EGFR) is often related to activation of other signaling pathways and evolution through a mesenchymal phenotype.File in questo prodotto:
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