A first solid phase approach to obtain monosubstituted CD conjugates to different labels has been developed. A new solid support has been designed to get a variety of C-6 monofunctionalized CDs (α, β, MeβCD and HPβCD) covalently linked through a phosphodiester bridge to different labels, in highly pure form and under very mild detachment conditions. © The Royal Society of Chemistry 2012.
A novel synthetic strategy for monosubstituted cyclodextrin derivatives
MALGIERI, Gaetano;ISERNIA, Carla;MESSERE, Anna;
2012
Abstract
A first solid phase approach to obtain monosubstituted CD conjugates to different labels has been developed. A new solid support has been designed to get a variety of C-6 monofunctionalized CDs (α, β, MeβCD and HPβCD) covalently linked through a phosphodiester bridge to different labels, in highly pure form and under very mild detachment conditions. © The Royal Society of Chemistry 2012.File in questo prodotto:
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