A biomimetic sensor based on molecularly imprinted polymer (MIP) and surface plasmon resonance(SPR) transduction, in connection with tapered plastic optical fiber (POF), has been developed for themarker-free, direct and selective detection of low molecular weight substances. The device has beenexperimentally tested for l-nicotine ((−)-1-methyl-2-(3-pyridyl)pyrrolidine, MW = 162.24). The sensorsystem developed made the selective and fast detection of l-nicotine possible, with a low cost, easy torealize and small sample volume procedure. The sensor can discriminate between l- and d-nicotine. Thelinearity range was from 0 to 10−3M, and the sensitivity strongly depended on the characteristics of thetapered fiber, ranging from 1.3 × 104nm/M, for a taper ratio 1.8, to 1.7 × 103nm/M for a taper ratio 1, i.e.a not-tapered fiber.
High selectivity and sensitivity sensor based on MIP and SPR in tapered plastic optical fibers for the detection of l-nicotine
N. Cennamo;ZENI, Luigi
2014
Abstract
A biomimetic sensor based on molecularly imprinted polymer (MIP) and surface plasmon resonance(SPR) transduction, in connection with tapered plastic optical fiber (POF), has been developed for themarker-free, direct and selective detection of low molecular weight substances. The device has beenexperimentally tested for l-nicotine ((−)-1-methyl-2-(3-pyridyl)pyrrolidine, MW = 162.24). The sensorsystem developed made the selective and fast detection of l-nicotine possible, with a low cost, easy torealize and small sample volume procedure. The sensor can discriminate between l- and d-nicotine. Thelinearity range was from 0 to 10−3M, and the sensitivity strongly depended on the characteristics of thetapered fiber, ranging from 1.3 × 104nm/M, for a taper ratio 1.8, to 1.7 × 103nm/M for a taper ratio 1, i.e.a not-tapered fiber.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
