We have investigated the role of bovine lactoferrin in protecting the intestinal epithelium from bacterial invasion. In particular, Caco-2, Chang Liver cells and primary culture hepatocytes were infected with L. monocytogenes (M.O.I. 100) in the presence of noncytotoxic, nonbactericidal concentrations of lactoferrin. The number of internalized bacteria was reduced by 50 to 100 fold in the presence of 1 mg/ml of bovine lactoferrin.

The effect of bovine lactoferrin on the invasiveness of Listeria monocytogenes in cultured cells

DONNARUMMA, Giovanna;
1998

Abstract

We have investigated the role of bovine lactoferrin in protecting the intestinal epithelium from bacterial invasion. In particular, Caco-2, Chang Liver cells and primary culture hepatocytes were infected with L. monocytogenes (M.O.I. 100) in the presence of noncytotoxic, nonbactericidal concentrations of lactoferrin. The number of internalized bacteria was reduced by 50 to 100 fold in the presence of 1 mg/ml of bovine lactoferrin.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11591/234522
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