A versatile synthesis of 1,6 - d-oligomannosides featuring the 1,4-disubstituted triazole ring as interglycosidic tether is presented via iterative copper(I)-catalyzed azide-alkyne cycloaddition. Free hydroxy hexamannoside and decamannoside featuring a capping 6-deoxymannose fragment have been prepared and characterized.

Studies toward the synthesis of inhibitors of mycobacterium tuberculosis cell-wall biosynthesis: The assembly of triazole-linked 1,6-a-D-oligomannosides via click CuAAC

CHAMBERY, Angela;
2009

Abstract

A versatile synthesis of 1,6 - d-oligomannosides featuring the 1,4-disubstituted triazole ring as interglycosidic tether is presented via iterative copper(I)-catalyzed azide-alkyne cycloaddition. Free hydroxy hexamannoside and decamannoside featuring a capping 6-deoxymannose fragment have been prepared and characterized.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11591/233498
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