Protein S is a vitamin K-dependent glycoprotein synthetized in the liver. It plays a majior anticoagulative role:it is the cofactor of the activated Protein C and controls coagulation, degrading the thrombin-activated factors V and VIII. The complex protein S/activated protein C also plays a role in controlling fibrinolysis. Protein S has two different forms: the free one(represents 40%) endowed with anticoagulative activity and the bound one, linked to the inhibitor of C4b complement(represents 60%);the latter has no anticoagulative function.
IL DOSAGGIO DELLA PROTEINA S NELLE DONNE GRAVIDE E NEGLI EPATOPATICI:TECNICHE ANALITICHE A CONFRONTO
LEPORE, Maria Antonietta
2000
Abstract
Protein S is a vitamin K-dependent glycoprotein synthetized in the liver. It plays a majior anticoagulative role:it is the cofactor of the activated Protein C and controls coagulation, degrading the thrombin-activated factors V and VIII. The complex protein S/activated protein C also plays a role in controlling fibrinolysis. Protein S has two different forms: the free one(represents 40%) endowed with anticoagulative activity and the bound one, linked to the inhibitor of C4b complement(represents 60%);the latter has no anticoagulative function.File in questo prodotto:
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