A novel antioxidant prenylated stilbenoid, distachyasin, has been isolated from the leaves of Carex distachya. Its structure has been elucidated on the basis of the spectroscopic characteristics. Bidimensional NMR, and crystallographic data and computational calculations have furnished important data useful for the characterization and the stereochemistry of the molecule. The compound has a tetracyclic skeleton derived from carexane. The compound has been assayed, for the antioxidant activity, by measuring its capacity to scavenge the H2O2, nitric oxide, superoxide radical and to inhibit formation of TBARS (thiobarbituric acid reactive species). © 2006 Elsevier Ltd. All rights reserved.
Distachyasin: A new antioxidant metabolite from the leaves of Carex distachya
FIORENTINO, Antonio;D'ABROSCA, Brigida;PACIFICO, Severina;IACOVINO, Rosa;MONACO, Pietro
2006
Abstract
A novel antioxidant prenylated stilbenoid, distachyasin, has been isolated from the leaves of Carex distachya. Its structure has been elucidated on the basis of the spectroscopic characteristics. Bidimensional NMR, and crystallographic data and computational calculations have furnished important data useful for the characterization and the stereochemistry of the molecule. The compound has a tetracyclic skeleton derived from carexane. The compound has been assayed, for the antioxidant activity, by measuring its capacity to scavenge the H2O2, nitric oxide, superoxide radical and to inhibit formation of TBARS (thiobarbituric acid reactive species). © 2006 Elsevier Ltd. All rights reserved.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
