LIPOMA DEL CORPO CALLOSO:CASO CLINICO E REVISIONE DELLA LETTERATURA

Intracranial lipomas are very rare congenital malformative lesions, being less than 0.1% of intracranial tumors. They originate from abnormal differentiation of mesenchimal tissue of meninx primitiva. Most of cases are asymptomatic pericallosal lesions, often associated with other defects of differentiation of the midline. Association with hypogenesis/agenesis of corpus callosum is frequent, being present in 90% of anterior lipomas and in 30% of posterior lipomas. We report a case of asymptomatic lipoma of corpus callosum associated with hypogenesis of corpus callosum, accidentally found, during diagnostic imaging of a female patient with early headache and no neurologic symptoms. Corpus callosum pure lesions are asymptomatic, that is they don’t affect commisural functions, so there’s no indication to surgical treatment. Other midline defects, that can be associated with pericallosal lipomas, are most frequently symptomatics. In lipomas of corpus callosum prognosis and symptoms depends on associated malformations.