Pezzolla A., Marzaioli R., Docimo G., Thyroglossal duct carcinoma (TDCa) is a rare, malignant tumor arising in a thyroglossal duct remnant (TDR) or a thyroglossal duct cyst (TDC). Controversies exist regarding origin as to whether it represents a metastatic lesion of a primary thyroid cancer versus its de novo origin. The case concerns a man with a visible and palpable subhyoid mass. Preoperative ultrasound scan and US-guided fine-needle aspiration cytology revealed suspicious papillary carcinoma in the TDC and thyroid nodules. Surgery consisted in removal of the hyoid bone and total thyroidectomy. Histopathologic examination revealed papillary TDCa and a focus of papillary var. follicular microcarcinoma in the thyroid gland. Ultrasound scan with fine-needle aspiration cytology has beneficial in the preoperative diagnosis of carcinoma in TDC. Surgery is an adequate treatment for TDCa and the prognosis is excellent. Adjuvant radioiodine and postoperative L-thiroxine sup- pressive therapy are appropriate in these cases. Our experience confirms the controversies about the origin of TDCa.
Thyroglossal duct carcinoma: report of a case
CONZO, Giovanni;
2014
Abstract
Pezzolla A., Marzaioli R., Docimo G., Thyroglossal duct carcinoma (TDCa) is a rare, malignant tumor arising in a thyroglossal duct remnant (TDR) or a thyroglossal duct cyst (TDC). Controversies exist regarding origin as to whether it represents a metastatic lesion of a primary thyroid cancer versus its de novo origin. The case concerns a man with a visible and palpable subhyoid mass. Preoperative ultrasound scan and US-guided fine-needle aspiration cytology revealed suspicious papillary carcinoma in the TDC and thyroid nodules. Surgery consisted in removal of the hyoid bone and total thyroidectomy. Histopathologic examination revealed papillary TDCa and a focus of papillary var. follicular microcarcinoma in the thyroid gland. Ultrasound scan with fine-needle aspiration cytology has beneficial in the preoperative diagnosis of carcinoma in TDC. Surgery is an adequate treatment for TDCa and the prognosis is excellent. Adjuvant radioiodine and postoperative L-thiroxine sup- pressive therapy are appropriate in these cases. Our experience confirms the controversies about the origin of TDCa.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
