In this concise review, we highlight the importance of the use of MSCs in bone diseases, focusing on the role of histone deacetylases and Wnt pathways involved in osteogenesis. A better understanding of MSC biology and osteogenesis is needed in order to develop new and targeted therapeutic strategies for the treatment of bone diseases/disorders
In questa review viene stressata l'importanza dell'uso delle MSCs per la rigenerazione ossea e valutati gli effetti delle deacetilasi istoniche e del pathway di Wnt per l'ossificazione.
Bone defects: molecular and cellular therapeutic targets.
DESIDERIO, Vincenzo;TIRINO, Virginia;PAPACCIO, Gianpaolo;PAINO, Francesca
2014
Abstract
In this concise review, we highlight the importance of the use of MSCs in bone diseases, focusing on the role of histone deacetylases and Wnt pathways involved in osteogenesis. A better understanding of MSC biology and osteogenesis is needed in order to develop new and targeted therapeutic strategies for the treatment of bone diseases/disordersFile in questo prodotto:
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