We present niobium-based Josephson devices as prototypes for applications to quantum computation with flux qubits. The most interesting feature of this device is the use of a Josephson vertical interferometer for a fine tuning of flux qubit and interquibit coupling. These devices allow a control of the off-diagonal Hamiltonian terms of flux qubit and of the flux transfer function of a superconducting transformer. In the vertical interferometer, the Josephson current is precisely modulated from a maximum to zero with fine control and precision by a small transversal magnetic field parallel to the radio-frequency superconducting loop plane and to the flux transformer. © 2005 American Institute of Physics. *DOI: 10.1063/1.2115083*