Two new ursolic acid triterpene derivatives, compounds 2 and 3, have been isolated from cv. Annurca apple fruit, a high-quality apple variety widely cultivated in southern Italy, together with the known 2-oxopomolic acid (1). The new compounds were identified by means of different spectroscopic techniques as 3-epi-2-oxopomolic acid (=(3α)-3,19-dihydroxy-2-oxours-12-en-28-oic acid; 2) and (1α)-1-hydroxy-3-oxours-12-en-28-oic acid (3). Compounds 1-3 were tested for their radical-scavenging activities with the aid of a 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay (Fig. 2). All three constituents showed activities similar to that of the reference antioxidant α-tocopherol (vitamin E). © 2005 Verlag Helvetica Chimica Acta AG, Zürich.
Titolo: | Radical-scavenging activities of new hydroxylated ursane triterpenes from cv. Annurca apples |
Autori: | |
Data di pubblicazione: | 2005 |
Rivista: | |
Abstract: | Two new ursolic acid triterpene derivatives, compounds 2 and 3, have been isolated from cv. Annurca apple fruit, a high-quality apple variety widely cultivated in southern Italy, together with the known 2-oxopomolic acid (1). The new compounds were identified by means of different spectroscopic techniques as 3-epi-2-oxopomolic acid (=(3α)-3,19-dihydroxy-2-oxours-12-en-28-oic acid; 2) and (1α)-1-hydroxy-3-oxours-12-en-28-oic acid (3). Compounds 1-3 were tested for their radical-scavenging activities with the aid of a 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay (Fig. 2). All three constituents showed activities similar to that of the reference antioxidant α-tocopherol (vitamin E). © 2005 Verlag Helvetica Chimica Acta AG, Zürich. |
Handle: | http://hdl.handle.net/11591/189437 |
Appare nelle tipologie: | 1.1 Articolo in rivista |