1. 1. The effect of a single injection of ethane-1,2-dimethane sulfonate (EDS) was studied in the teleost fish, Gobius paganellus in two different periods of the year. 2. 2. During June EDS did not induce any change, while during December the drug was highly effective in promoting testicular activity. 3. 3. Nucleus/cytoplasm ratio of interstitial cells strongly decreased concomitantly with the detection of high testicular androgen levels. 4. 4. The germinal compartment was well developed showing the appearance of all spermatogenic stages and the cavity of lobular compartments filled of spermatozoa. 5. 5. Our data are the first evidence of a stimulatory activity of EDS on testes of a vertebrate species. © 1992.
Resumption of testicular activity in Gobius paganellus after administration of ethane 1,2-dimethane sulfonate (EDS)
MINUCCI S;CHIEFFI BACCARI Gabriella;DI MATTEO;
1992
Abstract
1. 1. The effect of a single injection of ethane-1,2-dimethane sulfonate (EDS) was studied in the teleost fish, Gobius paganellus in two different periods of the year. 2. 2. During June EDS did not induce any change, while during December the drug was highly effective in promoting testicular activity. 3. 3. Nucleus/cytoplasm ratio of interstitial cells strongly decreased concomitantly with the detection of high testicular androgen levels. 4. 4. The germinal compartment was well developed showing the appearance of all spermatogenic stages and the cavity of lobular compartments filled of spermatozoa. 5. 5. Our data are the first evidence of a stimulatory activity of EDS on testes of a vertebrate species. © 1992.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
