Dermoscopy of Pigmented Lesions of the Vulva: A Retrospective Morphological Study

Ferrari, A; Zalaudek, I; Argenziano, Giuseppe; Buccini, P; De Simone, P; Silipo, V; Eibenschutz, L; Mariani, G; Covello, R; Sperduti, I; Mariani, L; Catricala, C.

doi:10.1159/000323409

Background: The dermoscopic patterns of pigmented skin tumors are influenced by the body site. Objective: To evaluate the clinical and dermoscopic features associated with pigmented vulvar lesions. Methods: Retrospective analysis of clinical and dermoscopic images of vulvar lesions. The chi(2) test was used to test the association between clinical data and histopathological diagnosis. Results: A total of 42 (32.8%) melanocytic and 86 (67.2%) nonmelanocytic vulvar lesions were analyzed. Nevi significantly prevailed in younger women compared with melanomas and melanosis and exhibited most commonly a globular/cobblestone (51.3%) and a mixed (21.6%) pattern. Dermoscopically all melanomas showed a multicomponent pattern. Melanotic macules showed clinical overlapping features with melanoma, but their dermoscopic patterns differed significantly from those observed in melanomas. Conclusion: The diagnosis and management of pigmented vulvar lesions should be based on a good clinicodermoscopic correlation. Dermoscopy may be helpful in the differentiation of solitary melanotic macules from early melanoma. Copyright (C) 2011 S. Karger AG, Basel

Titolo:	Dermoscopy of Pigmented Lesions of the Vulva: A Retrospective Morphological Study
Autori:	Ferrari A Zalaudek I ARGENZIANO, Giuseppe Buccini P De Simone P Silipo V Eibenschutz L Mariani G Covello R Sperduti I Mariani L Catricala C. mostra contributor esterni nascondi contributor esterni
Data di pubblicazione:	2011
Rivista:	DERMATOLOGY
Abstract:	Background: The dermoscopic patterns of pigmented skin tumors are influenced by the body site. Objective: To evaluate the clinical and dermoscopic features associated with pigmented vulvar lesions. Methods: Retrospective analysis of clinical and dermoscopic images of vulvar lesions. The chi(2) test was used to test the association between clinical data and histopathological diagnosis. Results: A total of 42 (32.8%) melanocytic and 86 (67.2%) nonmelanocytic vulvar lesions were analyzed. Nevi significantly prevailed in younger women compared with melanomas and melanosis and exhibited most commonly a globular/cobblestone (51.3%) and a mixed (21.6%) pattern. Dermoscopically all melanomas showed a multicomponent pattern. Melanotic macules showed clinical overlapping features with melanoma, but their dermoscopic patterns differed significantly from those observed in melanomas. Conclusion: The diagnosis and management of pigmented vulvar lesions should be based on a good clinicodermoscopic correlation. Dermoscopy may be helpful in the differentiation of solitary melanotic macules from early melanoma. Copyright (C) 2011 S. Karger AG, Basel
Handle:	http://hdl.handle.net/11591/184647
Appare nelle tipologie:	1.1 Articolo in rivista

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