The 4-substituted pyrimidine 2′,3′-dideoxy-2′,3′-didehydronucleosides 3 - 10 have been synthesized and the activity of compounds 8 - 10 against HIV evaluated. The synthesis of the 5′-phosphate derivatives 13 - 14 was also reported. © 1994.
SYNTHESIS OF 2',3'-DIDEOXY-2',3'-DIDEHYDRONUCLEOSIDE ANALOGS AS POTENTIAL ANTI-HIV AGENTS
MESSERE, Anna;
1992
Abstract
The 4-substituted pyrimidine 2′,3′-dideoxy-2′,3′-didehydronucleosides 3 - 10 have been synthesized and the activity of compounds 8 - 10 against HIV evaluated. The synthesis of the 5′-phosphate derivatives 13 - 14 was also reported. © 1994.File in questo prodotto:
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