Several studies have shown the efficacy of rituximab (RTX) in preventing relapses in patients suffering from Neuromyelitis Optica spectrum disorder (NMSOD) and have explored different therapeutic schemes. Given the extreme inter-individual variability of the disease course, there is the need to identify biomarkers to tailor the retreatment schedule and dosage. This review aimed to identify the most useful biomarker to guide reinfusion and, in turn, the optimal retreatment schedule of RTX for NMSOD.

Optimal retreatment schedule of rituximab for neuromyelitis optica spectrum disorder: A systematic review

Abbadessa, Gianmarco;Miele, Giuseppina;Maida, Elisabetta;Minervini, Giuseppe;Bonavita, Simona
2022

Abstract

Several studies have shown the efficacy of rituximab (RTX) in preventing relapses in patients suffering from Neuromyelitis Optica spectrum disorder (NMSOD) and have explored different therapeutic schemes. Given the extreme inter-individual variability of the disease course, there is the need to identify biomarkers to tailor the retreatment schedule and dosage. This review aimed to identify the most useful biomarker to guide reinfusion and, in turn, the optimal retreatment schedule of RTX for NMSOD.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11591/484453
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