Vitamin E is a lipid-soluble vitamin naturally synthesized by photosynthetic organisms (Yerin et al., 1984). The term “vitamin E” refers to a group of chemical compounds, tocols, and tocotrienols that act as antioxidant compounds and maintain the stability of cell membranes against oxidative stress. The antioxidant activity of vitamin E seems to be correlated with their capacity to quench free radicals and, in particular, reactive oxygen species produced by the cell metabolism. Vitamin E was discovered by Evans and Bishop (1922) and called “substance X” because it was essential to maintain rat fertility. The most active vitamer of vitamin E is α-tocopherol (from the Greek tokos = child, phero = to bear, and -ol indicating that the substance is an alcohol), isolated for the ‚rst time from wheat germ oil (Evans et al., 1936). © 2012 by Taylor & Francis Group, LLC.

Tocopherols, tocotrienols, and their bioactive analogs

PACIFICO, Severina;Scognamiglio M;D'ABROSCA, Brigida;MONACO, Pietro;FIORENTINO, Antonio
2012

Abstract

Vitamin E is a lipid-soluble vitamin naturally synthesized by photosynthetic organisms (Yerin et al., 1984). The term “vitamin E” refers to a group of chemical compounds, tocols, and tocotrienols that act as antioxidant compounds and maintain the stability of cell membranes against oxidative stress. The antioxidant activity of vitamin E seems to be correlated with their capacity to quench free radicals and, in particular, reactive oxygen species produced by the cell metabolism. Vitamin E was discovered by Evans and Bishop (1922) and called “substance X” because it was essential to maintain rat fertility. The most active vitamer of vitamin E is α-tocopherol (from the Greek tokos = child, phero = to bear, and -ol indicating that the substance is an alcohol), isolated for the ‚rst time from wheat germ oil (Evans et al., 1936). © 2012 by Taylor & Francis Group, LLC.
Pacifico, Severina; Scognamiglio, M; D'Abrosca, Brigida; Monaco, Pietro; Fiorentino, Antonio
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11591/321604
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