Defects of the skeletal system are an impediment to the normal function of the human organism. Problems still arise concerning the optimal therapy of bony defects after trauma or tumor resection. Today, biomaterials may be designed with the aim that once implanted they will help the body to heal itself. In particular, temporary matrices named scaffold with tailored morphological and functional properties may provide a specific environment and architecture able to promote the bone in-growth. Current work proposes a critical assessment of the most famous and recently used scaffold preparation strategies to emboss lights and shadows of the current bone regeneration in comparison with traditional approaches based on the tissue substitution.
Synthetic scaffolds: lights and shadows
RONCA, Dante;
2008
Abstract
Defects of the skeletal system are an impediment to the normal function of the human organism. Problems still arise concerning the optimal therapy of bony defects after trauma or tumor resection. Today, biomaterials may be designed with the aim that once implanted they will help the body to heal itself. In particular, temporary matrices named scaffold with tailored morphological and functional properties may provide a specific environment and architecture able to promote the bone in-growth. Current work proposes a critical assessment of the most famous and recently used scaffold preparation strategies to emboss lights and shadows of the current bone regeneration in comparison with traditional approaches based on the tissue substitution.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
