LDL cholesterol(LDL-C) has been the cornerstone measurement for assessing cardiovascular risk for nearly 10 years.Recent data demonstrate that apolipoprotein B (Apo-B) is a better measure of circulating LDL and the concentration is a more reliable indicator of risk than LDL-C.In this report,we review the studies of a apo B and LDL-C reported to date,discuss potential advantages of their measurement over that of LDL-C and the present information related to standardization. In line with recently guidelines,the addition of apo B represents a next most important step. Thus,it appears to consider using apo B along with LDL-C to asses LDL related risk for an period until the superiority of apo B is generally recognized. Recent genome-mitochondrial DNA association studies have pinpointed many loci associated with neurovegetative disease's. We have studied the association between genetic mutation factors on a whole mtDNA in longitudinal study design has enabled the investigation of genetic variation influencing trait values over time.
EMOSTASI E TROMBOFILIA.POLIMORFISMI GENETICI ASSOCIATI ALLE PATOLOGIE CARDIOVASCOLARI E NEUROVEGETATIVE
Lepore M. A.
Writing – Review & Editing
2016
Abstract
LDL cholesterol(LDL-C) has been the cornerstone measurement for assessing cardiovascular risk for nearly 10 years.Recent data demonstrate that apolipoprotein B (Apo-B) is a better measure of circulating LDL and the concentration is a more reliable indicator of risk than LDL-C.In this report,we review the studies of a apo B and LDL-C reported to date,discuss potential advantages of their measurement over that of LDL-C and the present information related to standardization. In line with recently guidelines,the addition of apo B represents a next most important step. Thus,it appears to consider using apo B along with LDL-C to asses LDL related risk for an period until the superiority of apo B is generally recognized. Recent genome-mitochondrial DNA association studies have pinpointed many loci associated with neurovegetative disease's. We have studied the association between genetic mutation factors on a whole mtDNA in longitudinal study design has enabled the investigation of genetic variation influencing trait values over time.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
