Objective. Osteoarthritis (OA) and osteoporosis are common diseases in older people but it is still not clear whether there is a correlation between them [1]. Trapeziometacarpal (TMC) OA is a common age-related degenerative disorder that might negatively influence the upper limb functioning. Aim of our study was to evaluate the influence of TMC OA severity on forearm bone mineral density (BMD) in a cohort post-menopausal women. Material and Methods. We included post-menopausal women, aged ≥50 years, with a diagnosis of TMC OA (according to the European League Against Rheumatism, EULAR, recommendations), with an Eaton-Glickel staging ≥2 [2]. We divided our cohort in 2 groups: mild TMC OA group (Eaton-Glickel staging 2) and moderate-severe TMC OA group (Eaton-Glickel staging 3-4). Outcome measures were: ultradistal radius (UDR) BMD, 33% radius BMD, lumbar spine (LS) BMD, and femoral neck (FN) BMD. Result s. We included 20 post-menopausal women, mean aged 68.65 ± 6.63 years, 11 with mild TMC OA and 9 with moderatesevere TMC OA. The moderate-severe TMC OA group had a significantly lower UDR BMD (0.313 ± 0.052 g/cm2 vs 0.436 ± 0.095 g/cm2; p=0.0088) and a significantly lower 33% radius BMD (0.584 ± 0.130 g/cm2 vs 0.778 ± 0.166 g/cm2; p=0.0062). No statistically significant differences were found in LS BMD and FN BMD between the two groups. Conclusion. Our data reported that TMC OA might have a negative impact on forearm bone health, as showed by the significantly lower UDR and 33% radius BMD in patients affected by moderate-severe TMC OA. On the other hand, no differences were found in the other skeletal sites. References 1. Dillon CF, Hirsch E, Rasch EK, Gu Q. Symptomatic hand osteoarthritis in the United States: prevalence and functional impairment estimates from the third U.S. National Health and Nutrition Examination Survey, 1991-1994. Am J Phys Med Rehabil 2007; 86:12-21. 2. Eaton RG, Littler JW. Ligament reconstruction for the painful thumb carpometacarpal joint. J Bone Joint Surg Am. 1973 Dec; 55(8):1655- 66.
IMPACT OF TRAPEZIOMETACARPAL OSTEOARTHRITIS SEVERITY ON FOREARM BONE MINERAL DENSITY IN A COHORT OF POSTMENOPAUSAL WOMEN
M. Paoletta;MORETTI A;F. Gimigliano;G. Iolascon
2018
Abstract
Objective. Osteoarthritis (OA) and osteoporosis are common diseases in older people but it is still not clear whether there is a correlation between them [1]. Trapeziometacarpal (TMC) OA is a common age-related degenerative disorder that might negatively influence the upper limb functioning. Aim of our study was to evaluate the influence of TMC OA severity on forearm bone mineral density (BMD) in a cohort post-menopausal women. Material and Methods. We included post-menopausal women, aged ≥50 years, with a diagnosis of TMC OA (according to the European League Against Rheumatism, EULAR, recommendations), with an Eaton-Glickel staging ≥2 [2]. We divided our cohort in 2 groups: mild TMC OA group (Eaton-Glickel staging 2) and moderate-severe TMC OA group (Eaton-Glickel staging 3-4). Outcome measures were: ultradistal radius (UDR) BMD, 33% radius BMD, lumbar spine (LS) BMD, and femoral neck (FN) BMD. Result s. We included 20 post-menopausal women, mean aged 68.65 ± 6.63 years, 11 with mild TMC OA and 9 with moderatesevere TMC OA. The moderate-severe TMC OA group had a significantly lower UDR BMD (0.313 ± 0.052 g/cm2 vs 0.436 ± 0.095 g/cm2; p=0.0088) and a significantly lower 33% radius BMD (0.584 ± 0.130 g/cm2 vs 0.778 ± 0.166 g/cm2; p=0.0062). No statistically significant differences were found in LS BMD and FN BMD between the two groups. Conclusion. Our data reported that TMC OA might have a negative impact on forearm bone health, as showed by the significantly lower UDR and 33% radius BMD in patients affected by moderate-severe TMC OA. On the other hand, no differences were found in the other skeletal sites. References 1. Dillon CF, Hirsch E, Rasch EK, Gu Q. Symptomatic hand osteoarthritis in the United States: prevalence and functional impairment estimates from the third U.S. National Health and Nutrition Examination Survey, 1991-1994. Am J Phys Med Rehabil 2007; 86:12-21. 2. Eaton RG, Littler JW. Ligament reconstruction for the painful thumb carpometacarpal joint. J Bone Joint Surg Am. 1973 Dec; 55(8):1655- 66.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
