Migraine arises from a primary brain dysfunction that leads to episodic activation and sensitization of the trigeminovascular pain pathway. About one third of patients with migraine experiences transient neurological symptoms during attacks, so-called “aura”, among which the most common is visual aura [1]. In our previous fMRI study, we had observed a significantly increased resting-state visual network (RS-VN) functional connectivity in patients with migraine with aura (MwA) compared to patients with migraine without aura (MwoA) during the interictal period [2]. Nevertheless, both whole-brain and visual pathways microstructural white matter (WM) abnormalities in patients with MwA and MwoA is still under debate.
P020. No evidence of microstructural changes in visual network in patients with migraine with aura: a diffusion tensor tract-based spatial statistic (TBSS) study
RUSSO, Antonio;CONFORTI, Renata;Esposito, Fabrizio;TESSITORE, Alessandro;TEDESCHI, Gioacchino
2015
Abstract
Migraine arises from a primary brain dysfunction that leads to episodic activation and sensitization of the trigeminovascular pain pathway. About one third of patients with migraine experiences transient neurological symptoms during attacks, so-called “aura”, among which the most common is visual aura [1]. In our previous fMRI study, we had observed a significantly increased resting-state visual network (RS-VN) functional connectivity in patients with migraine with aura (MwA) compared to patients with migraine without aura (MwoA) during the interictal period [2]. Nevertheless, both whole-brain and visual pathways microstructural white matter (WM) abnormalities in patients with MwA and MwoA is still under debate.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
