When bioactive coatings are applied to medical implants by means of sol-gel dip coating technique, the biological proprieties of the implant surface can be modified to match the properties of the surrounding tissues. In this study, sol-gel method is used to synthesized organic-inorganic nanocomposites materials consisting of an inorganic titania matrix in which 10 wt% of a biodegradable polymer, the poly-ε-caprolactone (PCL), was incorporated. The synthesized materials, in sol phase, were used to dip-coat a commercially pure titanium grade 4 substrate in order to improve its surface biological properties. Materials were characterized using Fourier transform infrared spectroscopy (FT-IR) and a morphological analysis of the obtained films was performed via scanning electron microscopy (SEM). Coating bioactivity was investigated by soaking coated substrates in a fluid simulating the human blood plasma (SBF) and successively evaluating the formation of a hydroxyapatite layer on their surface by means of SEM/EDX (energy dispersive X-ray).
TiO2/PCL Hybrid Layers Prepared via Sol-Gel Dip Coating for the Surface Modification of Titanium Implants: Characterization and Bioactivity Evaluation
CATAURO, Michelina;BOLLINO, Flavia;PAPALE, FERDINANDO;LAMANNA, Giuseppe
2015
Abstract
When bioactive coatings are applied to medical implants by means of sol-gel dip coating technique, the biological proprieties of the implant surface can be modified to match the properties of the surrounding tissues. In this study, sol-gel method is used to synthesized organic-inorganic nanocomposites materials consisting of an inorganic titania matrix in which 10 wt% of a biodegradable polymer, the poly-ε-caprolactone (PCL), was incorporated. The synthesized materials, in sol phase, were used to dip-coat a commercially pure titanium grade 4 substrate in order to improve its surface biological properties. Materials were characterized using Fourier transform infrared spectroscopy (FT-IR) and a morphological analysis of the obtained films was performed via scanning electron microscopy (SEM). Coating bioactivity was investigated by soaking coated substrates in a fluid simulating the human blood plasma (SBF) and successively evaluating the formation of a hydroxyapatite layer on their surface by means of SEM/EDX (energy dispersive X-ray).I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
