Sleep pressure score and neuropsychological impairment in childhood migraine

Introduction Migraine is recognized as a primarily neural condition, with changes in neural physiology. Several reports suggest relationship and/or comorbidity between sleep disorders and headache, linked to common pathophysiological substrates. Moreover, sleep-disordered breathing (SDB) and excessive daytime sleepiness (EDS) are more frequent compared to children from a normative community sample. It is well known that in SDB, reciprocal changes in the frequency of spontaneous and respiratoryrelated arousals occur with increasing SDB severity in children and that a sleep pressure score (SPS) could be developed to potentially reflect mounting sleep pressure in children who breath abnormally during sleep and could explain their neuropsychological impairment