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Risultati 291 - 300 di 20423 (tempo di esecuzione: 0.022 secondi).
Titolo Data di pubblicazione Autore(i) File
[The Ponseti approach for the treatment of congenital clubfoot]. 1-gen-2012 Riccio, Ilaria; Riccio, V; Riccardi, D; Esposito, M; Riccardi, Giovanni
[THU0309] CLINICAL MANIFESTATIONS IN LATE VS EARLY –ONSET SYSTEMIC SCLEROSIS (SSC) G. Cuomo, M. Iudici, G. Abignano, G. Valentini. Second Universty of Naples, Rheumatology Unit, Naples, Italy Background: Differences have been so far pointed out in the clinical manifestations and disease course in patients with a number of autoimmune rheumatic diseases and different age at onset (1-3). Objectives: To investigate the occurrence of differences between early and late onset SSc. Methods: 260 SSc patients (233 females) with a median age at the onset of the disease of 40.5 years (range 8-74) were consecutively admitted to a tertiary centre from November 1st 2000 to October 31st 2008. They were divided into 2 groups: early onset (<40.5 years) and late onset (≥40.5 years). Differences in each of the epidemiological, clinical and serological aspects collected in all the patients at admission were analysed. Results: Table 1 lists the significant differences detected between the 2 groups. Early onset patients were found to have a longer disease duration at presentation, a higher prevalence of anti-Scl70 positivity and a higher prevalence of scleroderma renal crisis; a lower prevalence of antinucleolar antibody positivity; a lower percentage of pulmonary hypertension; a lower HAQ-DI and a lower prevalence of heart involvement. No difference was detected in clinical subset distribution. Late onset (138) Early onset (122) p Disease duration mean (sd) 6 (6) 10 (10) 0.003 Range (median) 0.5-26 (5) 0.5-45 (6) Serological subset Scl70 43 54 0.04 Nucleolar 9 23 0.004 PAPs ≥40mmHG (echocardiography) 14/124 3/119 0.01 HAQ-DI mean (sd) 0.65 (0.7) 0.5 (0.7) 0.037 Range (median) 0-0.275 (0.375) 0-0.25 (0.125) Severity scale Late onset (138) Early onset(122) p 0-1 2-3-4 0-1 2-3-4 Heart 117 21 121 1 <0.0001 Kidney 138 0 117 5 0.02 Conclusion: Our study demonstrate that similarly to systemic lupus erithematosus and rheumatoid arthritis, distinct differences related to age at onset also occur in SSc patients. References: • Calvo-Alen J. et al, Clin Rheumatol 2005 • Lalani S. et al, J Rheumatol 2010 • Ho CT et al, Ann Rheum 1998 Disclosure of Interest: None declared Citation: Ann Rheum Dis 2010;69(Suppl3):247 Session: Scleroderma, Myositis and related syndromes 1-gen-2010 Cuomo, Giovanna; Iudici, M.; Abignano, G.; Valentini, G.
[Unclear clinical change on the glans penis leads to different dermoscopic diagnoses.] 1-gen-2013 Blum, A; Kittler, H; Zalaudek, I; Simionescu, O; Marghoob, Aa; Hofmann Wellenhof, R; Argenziano, Giuseppe; Soyer, Hp
[Use of ECG-EC in the positioning of central venous catheters]. 1-gen-2012 Calabria, M; Zamboli, Pasquale; D'Amelio, A; Granata, A; Di Lullo, L; Floccari, F; Logias, F; Fiorini, F; Gruppo di Studio di Ecografia Renale della Societa' Italiana di, Nefrologia
A combined fermentative-chemical approach for the scalable production of pure E. coli monophosphoryl lipid A. 1-gen-2014 Pieretti, G; Cipolletti, M; D'Alonzo, D; Alfano, A; Cimini, Donatella; Cammarota, M; Palumbo, G; Giuliano, M; DE ROSA, Mario; Schiraldi, Chiara; Parrilli, M; Bedini, E; Corsaro, M. M.
A "new" indication for the insulin pump: poor compliance of the teachers 1-gen-2010 Iafusco, Dario; Galderisi, A; Russo, L; Casaburo, F; Prisco, F.
A "systems medicine" approach to the study of non-alcoholic fatty liver disease 1-gen-2016 Petta, S; Valenti, L; Bugianesi, E; Targher, G; Bellentani, S; Bonino, F; Ferrannini, E; Loguercio, Carmelina; Lonardo, A; Marra, F; Mancini, M; Miele, L; Nobili, V; Baroni, Gs; Federico, Alessandro; Ballestri, S; Rossana Brunetto, M; Coco, B; Grieco, A; Fargion, S; Kondili, L; Nascimbeni, F; Prinster, A; Romagnoli, D; Taddei, S; Vanni, E; Vella, S.
A 'Geo-Pedo-Fingerprint' (GPF) as a tracer to detect univocal parent material-to-wine production chain in high quality vineyard districts, Campi Flegrei (Southern Italy) 1-gen-2014 Mercurio, M; Grilli, E; Odierna, P; Morra, V; Prohaska, T; Coppola, Elio; Grifa, C; Buondonno, Andrea; Langella, A.
A 2-year comparative open label randomized study of efficacy and safety of etanercept and infliximab in patients with ankylosing spondylitis 1-gen-2010 Giardina, A.; Ferrante, Angelo; Ciccia, Francesco; Impastato, Rosalia; Miceli, M.; Principato, A.; Triolo, Giovanni
A 3D electromagnetic model of the iron core in JET 1-gen-2017 Chiariello, A. G.; Ledda, F.; Martone, R.; Murari, A.; Pizzo, F.; Rimini, F.
Risultati 291 - 300 di 20423 (tempo di esecuzione: 0.022 secondi).
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