MEGCHELENBRINK, Wouter Leonard
MEGCHELENBRINK, Wouter Leonard
Dipartimento di Medicina di Precisione
Deregulation of new cell death mechanisms in Leukemia
2024 Favale, Gregorio; Donnarumma, Federica; Capone, Vincenza; DELLA TORRE, Laura; Beato, Antonio; Carannante, Daniela; Verrilli, Giulia; Nawaz, Asmat; Grimaldi, Francesco; Carla De Simone, Maria; DEL GAUDIO, Nunzio; Megchelenbrink, Wouter Leonard; Caraglia, Michele; Benedetti, Rosaria; Altucci, Lucia; Carafa, Vincenzo
Divergent WNT signaling and drug sensitivity profiles within hepatoblastoma tumors and organoids
2024 Kluiver, Thomas A; Lu, Yuyan; Schubert, Stephanie A; Kraaier, Lianne J; Ringnalda, Femke; Lijnzaad, Philip; Demartino, Jeff; Megchelenbrink, Wouter L; Amo-Addae, Vicky; Eising, Selma; de Faria, Flavia W; Münter, Daniel; van de Wetering, Marc; Kerl, Kornelius; Duiker, Evelien; van den Heuvel, Marius C; de Meijer, Vincent E; de Kleine, Ruben H; Molenaar, Jan J; Margaritis, Thanasis; Stunnenberg, Hendrik G; de Krijger, Ronald R; Zsiros, József; Clevers, Hans; Peng, Weng Chuan
Dynamic CpG methylation delineates subregions within super-enhancers selectively decommissioned at the exit from naive pluripotency
2020 Bell, E.; Curry, E. W.; Megchelenbrink, W.; Jouneau, L.; Brochard, V.; Tomaz, R. A.; Mau, K. H. T.; Atlasi, Y.; de Souza, R. A.; Marks, H.; Stunnenberg, H. G.; Jouneau, A.; Azuara, V.
Epigenetic modulation of a hardwired 3D chromatin landscape in two naive states of pluripotency
2019 Atlasi, Y.; Megchelenbrink, W.; Peng, T.; Habibi, E.; Joshi, O.; Wang, S. -Y.; Wang, C.; Logie, C.; Poser, I.; Marks, H.; Stunnenberg, H. G.
Epigenomic machinery regulating pediatric AML: clonal expansion mechanisms, therapies, and future perspectives
2023 Chianese, Ugo; Papulino, Chiara; Megchelenbrink, Wout; Tambaro, Francesco Paolo; Ciardiello, Fortunato; Benedetti, Rosaria; Altucci, Lucia
Estimating metabolic fluxes using a maximum network flexibility paradigm
2015 Megchelenbrink, W.; Rossell, S.; Huynen, M. A.; Notebaart, R. A.; Marchiori, E.
Extensive epigenomic integration of the glucocorticoid response in primary human monocytes and in vitro derived macrophages
2019 Wang, C.; Nanni, L.; Novakovic, B.; Megchelenbrink, W.; Kuznetsova, T.; Stunnenberg, H. G.; Ceri, S.; Logie, C.
Extensive patient-to-patient single nucleus transcriptome heterogeneity in pheochromocytomas and paragangliomas
2022 Brazda, Peter; Ruiz-Moreno, Cristian; Megchelenbrink, Wout L; Timmers, Henri J L M; Stunnenberg, Hendrik G
Inverse FASN and LDHA correlation drives metabolic resistance in breast cancer
2024 Papulino, Chiara; Chianese, Ugo; Ali, Ahmad; Favale, Gregorio; Tuccillo, Concetta; Ciardiello, Fortunato; Di Mauro, Annabella; Mignogna, Chiara; Ferrara, Gerardo; Budillon, Alfredo; Megchelenbrink, Wouter Leonard; Del Gaudio, Nunzio; Conte, Mariarosaria; Merciai, Fabrizio; Campiglia, Pietro; Altucci, Lucia; Carafa, Vincenzo; Sommella, Eduardo; Benedetti, Rosaria
Involvement of regulated cell deaths in aging and age-related pathologies
2024 Della Torre, Laura; Beato, Antonio; Capone, Vincenza; Carannante, Daniela; Verrilli, Giulia; Favale, Gregorio; Del Gaudio, Nunzio; Megchelenbrink, Wouter Leonard; Benedetti, Rosaria; Altucci, Lucia; Carafa, Vincenzo
Longitudinal single-cell transcriptomics reveals distinct patterns of recurrence in acute myeloid leukemia
2022 Zhai, Yanan; Singh, Prashant; Dolnik, Anna; Brazda, Peter; Atlasy, Nader; del Gaudio, Nunzio; Döhner, Konstanze; Döhner, Hartmut; Minucci, Saverio; Martens, Joost; Altucci, Lucia; Megchelenbrink, Wout; Bullinger, Lars; Stunnenberg, Hendrik G.
NOVEL GENES INVOLVED IN NEUROPATHIC PAIN IN PATIENTS
2016 Szklarczyk, R; Megchelenbrink, W; Cizek, P; Ledent, M; Velemans, G; Szklarczyk, D; Huynen, M; Momani, R; Gerrits, M; Faber, K; Smeets, B
optGpSampler: An improved tool for uniformly sampling the solution-space of genome-scale metabolic networks
2014 Megchelenbrink, W.; Huynen, M.; Marchiori, E.
PC: Epigenetic modulation of a hardwired 3D chromatin landscape in two naive states of pluripotency
2019 Atlasi, Yaser; Megchelenbrink, Wout; Peng, Tianran; Habibi, Ehsan; Joshi, Onkar; Wang, Shuang-Yin; Wang, Cheng; Logie, Colin; Poser, Ina; Marks, Hendrik; Stunnenberg, Hendrik G
Predicting human genetic interactions from cancer genome evolution
2015 Lu, X.; Megchelenbrink, Wouter Leonard; Notebaart, R. A.; Huynen, M. A.
SPATIAL ORGANIZATION OF THE PEDIATRIC HIGH-GRADE GLIOMA TUMOR-IMMUNE LANDSCAPE
2023 van den Broek, T; Hoogendijk, R; Kranendonk, M; Ruiz, C; Megchelenbrink, Wl; Lammers, J; Ries, Mg; Hoving, E; van der Lugt, J; Rios, Ac; Stunnenberg, H; van Vuurden, D; Zomer, A
STARR-seq identifies active, chromatin-masked, and dormant enhancers in pluripotent mouse embryonic stem cells
2020 Peng, Tianran; Zhai, Yanan; Atlasi, Yaser; Ter Huurne, Menno; Marks, Hendrik; Stunnenberg, Hendrik G; Megchelenbrink, Wout
Synthetic dosage lethality in the human metabolic network is highly predictive of tumor growth and cancer patient survival
2015 Megchelenbrink, W.; Katzir, R.; Lu, X.; Ruppin, E.; Notebaart, R. A.
The m6A-independent role of epitranscriptomic factors in cancer
2024 Bove, Guglielmo; Crepaldi, Marco; Amin, Sajid; Megchelenbrink, Wouter Leonard; Nebbioso, Angela; Carafa, Vincenzo; Altucci, Lucia; DEL GAUDIO, Nunzio
Trained innate immunity, long-lasting epigenetic modulation, and skewed myelopoiesis by heme
2021 Jentho, E; Ruiz-Moreno, C; Novakovic, B; Kourtzelis, I; Megchelenbrink, Wl; Martins, R; Chavakis, T; Soares, Mp; Kalafati, L; Guerra, J; Roestel, F; Bohm, P; Godmann, M; Grinenko, T; Eugster, A; Beretta, M; Joosten, Lab; Netea, Mg; Bauer, M; Stunnenberg, Hg; Weis, S
Titolo | Data di pubblicazione | Autore(i) | File |
---|---|---|---|
Deregulation of new cell death mechanisms in Leukemia | 1-gen-2024 | Favale, Gregorio; Donnarumma, Federica; Capone, Vincenza; DELLA TORRE, Laura; Beato, Antonio; Carannante, Daniela; Verrilli, Giulia; Nawaz, Asmat; Grimaldi, Francesco; Carla De Simone, Maria; DEL GAUDIO, Nunzio; Megchelenbrink, Wouter Leonard; Caraglia, Michele; Benedetti, Rosaria; Altucci, Lucia; Carafa, Vincenzo | |
Divergent WNT signaling and drug sensitivity profiles within hepatoblastoma tumors and organoids | 1-gen-2024 | Kluiver, Thomas A; Lu, Yuyan; Schubert, Stephanie A; Kraaier, Lianne J; Ringnalda, Femke; Lijnzaad, Philip; Demartino, Jeff; Megchelenbrink, Wouter L; Amo-Addae, Vicky; Eising, Selma; de Faria, Flavia W; Münter, Daniel; van de Wetering, Marc; Kerl, Kornelius; Duiker, Evelien; van den Heuvel, Marius C; de Meijer, Vincent E; de Kleine, Ruben H; Molenaar, Jan J; Margaritis, Thanasis; Stunnenberg, Hendrik G; de Krijger, Ronald R; Zsiros, József; Clevers, Hans; Peng, Weng Chuan | |
Dynamic CpG methylation delineates subregions within super-enhancers selectively decommissioned at the exit from naive pluripotency | 1-gen-2020 | Bell, E.; Curry, E. W.; Megchelenbrink, W.; Jouneau, L.; Brochard, V.; Tomaz, R. A.; Mau, K. H. T.; Atlasi, Y.; de Souza, R. A.; Marks, H.; Stunnenberg, H. G.; Jouneau, A.; Azuara, V. | |
Epigenetic modulation of a hardwired 3D chromatin landscape in two naive states of pluripotency | 1-gen-2019 | Atlasi, Y.; Megchelenbrink, W.; Peng, T.; Habibi, E.; Joshi, O.; Wang, S. -Y.; Wang, C.; Logie, C.; Poser, I.; Marks, H.; Stunnenberg, H. G. | |
Epigenomic machinery regulating pediatric AML: clonal expansion mechanisms, therapies, and future perspectives | 1-gen-2023 | Chianese, Ugo; Papulino, Chiara; Megchelenbrink, Wout; Tambaro, Francesco Paolo; Ciardiello, Fortunato; Benedetti, Rosaria; Altucci, Lucia | |
Estimating metabolic fluxes using a maximum network flexibility paradigm | 1-gen-2015 | Megchelenbrink, W.; Rossell, S.; Huynen, M. A.; Notebaart, R. A.; Marchiori, E. | |
Extensive epigenomic integration of the glucocorticoid response in primary human monocytes and in vitro derived macrophages | 1-gen-2019 | Wang, C.; Nanni, L.; Novakovic, B.; Megchelenbrink, W.; Kuznetsova, T.; Stunnenberg, H. G.; Ceri, S.; Logie, C. | |
Extensive patient-to-patient single nucleus transcriptome heterogeneity in pheochromocytomas and paragangliomas | 1-gen-2022 | Brazda, Peter; Ruiz-Moreno, Cristian; Megchelenbrink, Wout L; Timmers, Henri J L M; Stunnenberg, Hendrik G | |
Inverse FASN and LDHA correlation drives metabolic resistance in breast cancer | 1-gen-2024 | Papulino, Chiara; Chianese, Ugo; Ali, Ahmad; Favale, Gregorio; Tuccillo, Concetta; Ciardiello, Fortunato; Di Mauro, Annabella; Mignogna, Chiara; Ferrara, Gerardo; Budillon, Alfredo; Megchelenbrink, Wouter Leonard; Del Gaudio, Nunzio; Conte, Mariarosaria; Merciai, Fabrizio; Campiglia, Pietro; Altucci, Lucia; Carafa, Vincenzo; Sommella, Eduardo; Benedetti, Rosaria | |
Involvement of regulated cell deaths in aging and age-related pathologies | 1-gen-2024 | Della Torre, Laura; Beato, Antonio; Capone, Vincenza; Carannante, Daniela; Verrilli, Giulia; Favale, Gregorio; Del Gaudio, Nunzio; Megchelenbrink, Wouter Leonard; Benedetti, Rosaria; Altucci, Lucia; Carafa, Vincenzo | |
Longitudinal single-cell transcriptomics reveals distinct patterns of recurrence in acute myeloid leukemia | 1-gen-2022 | Zhai, Yanan; Singh, Prashant; Dolnik, Anna; Brazda, Peter; Atlasy, Nader; del Gaudio, Nunzio; Döhner, Konstanze; Döhner, Hartmut; Minucci, Saverio; Martens, Joost; Altucci, Lucia; Megchelenbrink, Wout; Bullinger, Lars; Stunnenberg, Hendrik G. | |
NOVEL GENES INVOLVED IN NEUROPATHIC PAIN IN PATIENTS | 1-gen-2016 | Szklarczyk, R; Megchelenbrink, W; Cizek, P; Ledent, M; Velemans, G; Szklarczyk, D; Huynen, M; Momani, R; Gerrits, M; Faber, K; Smeets, B | |
optGpSampler: An improved tool for uniformly sampling the solution-space of genome-scale metabolic networks | 1-gen-2014 | Megchelenbrink, W.; Huynen, M.; Marchiori, E. | |
PC: Epigenetic modulation of a hardwired 3D chromatin landscape in two naive states of pluripotency | 1-gen-2019 | Atlasi, Yaser; Megchelenbrink, Wout; Peng, Tianran; Habibi, Ehsan; Joshi, Onkar; Wang, Shuang-Yin; Wang, Cheng; Logie, Colin; Poser, Ina; Marks, Hendrik; Stunnenberg, Hendrik G | |
Predicting human genetic interactions from cancer genome evolution | 1-gen-2015 | Lu, X.; Megchelenbrink, Wouter Leonard; Notebaart, R. A.; Huynen, M. A. | |
SPATIAL ORGANIZATION OF THE PEDIATRIC HIGH-GRADE GLIOMA TUMOR-IMMUNE LANDSCAPE | 1-gen-2023 | van den Broek, T; Hoogendijk, R; Kranendonk, M; Ruiz, C; Megchelenbrink, Wl; Lammers, J; Ries, Mg; Hoving, E; van der Lugt, J; Rios, Ac; Stunnenberg, H; van Vuurden, D; Zomer, A | |
STARR-seq identifies active, chromatin-masked, and dormant enhancers in pluripotent mouse embryonic stem cells | 1-gen-2020 | Peng, Tianran; Zhai, Yanan; Atlasi, Yaser; Ter Huurne, Menno; Marks, Hendrik; Stunnenberg, Hendrik G; Megchelenbrink, Wout | |
Synthetic dosage lethality in the human metabolic network is highly predictive of tumor growth and cancer patient survival | 1-gen-2015 | Megchelenbrink, W.; Katzir, R.; Lu, X.; Ruppin, E.; Notebaart, R. A. | |
The m6A-independent role of epitranscriptomic factors in cancer | 1-gen-2024 | Bove, Guglielmo; Crepaldi, Marco; Amin, Sajid; Megchelenbrink, Wouter Leonard; Nebbioso, Angela; Carafa, Vincenzo; Altucci, Lucia; DEL GAUDIO, Nunzio | |
Trained innate immunity, long-lasting epigenetic modulation, and skewed myelopoiesis by heme | 1-gen-2021 | Jentho, E; Ruiz-Moreno, C; Novakovic, B; Kourtzelis, I; Megchelenbrink, Wl; Martins, R; Chavakis, T; Soares, Mp; Kalafati, L; Guerra, J; Roestel, F; Bohm, P; Godmann, M; Grinenko, T; Eugster, A; Beretta, M; Joosten, Lab; Netea, Mg; Bauer, M; Stunnenberg, Hg; Weis, S |