POROTTO, Matteo
POROTTO, Matteo
Dipartimento di Medicina Sperimentale
A broad-spectrum antiviral targeting entry of enveloped viruses
2010 Wolf, Mike C.; Freiberg, Alexander N.; Zhang, Tinghu; Akyol-Ataman, Zeynep; Grock, Andrew; Hong, Patrick W.; Li, Jianrong; Watson, Natalya F.; Fang, Angela Q.; Aguilar, Hector C.; Porotto, Matteo; Honko, Anna N.; Damoiseaux, Robert; Miller, John P.; Woodson, Sara E.; Chantasirivisal, Steven; Fontanes, Vanessa; Negrete, Oscar A.; Krogstad, Paul; Dasgupta, Asim; Moscona, Anne; Hensley, Lisa E.; Whelan, Sean P.; Faull, Kym F.; Holbrook, Michael R.; Jung, Michael E.; Lee, Benhur
A general strategy to endow natural fusion-protein-derived peptides with potent antiviral activity
2012 Pessi, Antonello; Langella, Annunziata; Capitã², Elena; Ghezzi, Silvia; Vicenzi, Elisa; Poli, Guido; Ketas, Thomas; Mathieu, Cyrille; Cortese, Riccardo; Horvat, Branka; Moscona, Anne; Porotto, Matteo
A neutralizing antibody prevents postfusion transition of measles virus fusion protein
2024 Zyla, Dawid S; Della Marca, Roberta; Niemeyer, Gele; Zipursky, Gillian; Stearns, Kyle; Leedale, Cameron; Sobolik, Elizabeth B; Callaway, Heather M; Hariharan, Chitra; Peng, Weiwei; Parekh, Diptiben; Marcink, Tara C; Diaz Avalos, Ruben; Horvat, Branka; Mathieu, Cyrille; Snijder, Joost; Greninger, Alexander L; Hastie, Kathryn M; Niewiesk, Stefan; Moscona, Anne; Porotto, Matteo; Ollmann Saphire, Erica
A rapid high-throughput assay for the identification of neutralizing antibodies and antiviral molecules against SARS-CoV-2 virus
2020 Stelitano, D; Bovier, F T; Mathieu, C; Horvat, B; Zannella, C; Folliero, V; Franci, G; Cennamo, M; Portella, G; Galdiero, M; Porotto, M
A recombinant sialidase fusion protein effectively inhibits human parainfluenza viral infection in vitro and in vivo
2010 Moscona, Anne; Porotto, Matteo; Palmer, Samantha; Tai, Caroline; Aschenbrenner, Lori; Triana-Baltzer, Gallen; Li, Qi-Xiang; Wurtman, David; Niewiesk, Stefan; Fang, Fang
A second receptor binding site on human parainfluenza virus type 3 hemagglutinin-neuraminidase contributes to activation of the fusion mechanism
2007 Porotto, Matteo; Fornabaio, Micaela; Kellogg, Glen E.; Moscona, Anne
A single amino acid alteration in the human parainfluenza virus type 3 hemagglutinin-neuraminidase glycoprotein confers resistance to the inhibitory effects of zanamivir on receptor binding and neuraminidase activity
2001 Murrell, M. T.; Porotto, M.; Greengard, O.; Poltoratskaia, N.; Moscona, A.
A three-dimensional model of human lung development and disease from pluripotent stem cells
2017 Chen, Ya-Wen; Huang, Sarah Xuelian; De Carvalho, Ana Luisa Rodrigues Toste; Ho, Siu-Hong; Islam, Mohammad Naimul; Volpi, Stefano; Notarangelo, Luigi D.; Ciancanelli, Michael; Casanova, Jean-Laurent; Bhattacharya, Jahar; Liang, Alice F.; Palermo, Laura M.; Porotto, Matteo; Moscona, Anne; Snoeck, Hans-Willem
Absence of COVID-19-associated changes in plasma coagulation proteins and pulmonary thrombosis in the ferret model
2022 Kreft, Iris C; Winiarczyk, Roy R A; Tanis, Fric J; van der Zwaan, Carmen; Schmitz, Katharina S; Hoogendijk, Arie J; de Swart, Rik L; Moscona, Anne; Porotto, Matteo; Salvatori, Daniela C F; de Vries, Rory D; de Maat, Moniek P M; van den Biggelaar, Maartje; van Vlijmen, Bart J M
Adaptation of human parainfluenza virus to airway epithelium reveals fusion properties required for growth in host tissue
2012 Palmer, Samantha G.; Porotto, Matteo; Palermo, Laura M.; Cunha, Luis F.; Greengard, Olga; Moscona, Anne
Analysis of a subacute sclerosing panencephalitis (SSPE) Genotype B3 virus from the 2009/10 South African measles epidemic shows hyperfusogenic F proteins contribute to measles virus infection in the brain
2019 Angius, Fabrizio; Smuts, Heidi; Rybkina, Ksenia; Stelitano, Debora; Eley, Brian; Wilmshurst, Jo; Ferren, Marion; Lalande, Alexandre; Mathieu, Cyrille; Moscona, Anne; Horvat, Branka; Hashiguchi, Takao; Porotto, Matteo; Hardie, Diana
Antiviral activity of gliotoxin, gentian violet and brilliant green against Nipah and Hendra virus in vitro
2009 Aljofan, Mohamad; Sganga, Michael L.; Lo, Michael K.; Rootes, Christina L.; Porotto, Matteo; Meyer, Adam G.; Saubern, Simon; Moscona, Anne; Mungall, Bruce A.
Antiviral activity of nitazoxanide against Morbillivirus infections
2023 Stelitano, Debora; La Frazia, Simone; Ambrosino, Annalisa; Zannella, Carla; Tay, Daniel; Iovane, Valentina; Montagnaro, Serena; De Filippis, Anna; Santoro, Maria Gabriella; Porotto, Matteo; Galdiero, Massimiliano
Antiviral Lipopeptide-Cell Membrane Interaction Is Influenced by PEG Linker Length
2017 Augusto, Marcelo T; Hollmann, Axel; Porotto, Matteo; Moscona, Anne; Santos, Nuno C.
Authentic modeling of human respiratory virus infection in human pluripotent stem cell-derived lung organoids
2019 Porotto, M.; Ferren, M.; Chen, Y. -W.; Siu, Y.; Makhsous, N.; Rima, B.; Briese, T.; Greninger, A. L.; Snoeck, H. -W.; Moscona, A.
Biophysical properties and antiviral activities of measles fusion protein derived peptide conjugated with 25-hydroxycholesterol
2017 Gomes, Bã¡rbara; Santos, Nuno C.; Porotto, Matteo
Broad spectrum antiviral activity for paramyxoviruses is modulated by biophysical properties of fusion inhibitory peptides
2017 Mathieu, Cyrille; Augusto, Marcelo T; Niewiesk, Stefan; Horvat, Branka; Palermo, Laura M; Sanna, Giuseppina; Madeddu, Silvia; Huey, Devra; Castanho, Miguel A. R. B; Porotto, Matteo; Santos, Nuno C; Moscona, Anne
Capturing a fusion intermediate of influenza hemagglutinin with a cholesterol-conjugated peptide, a new antiviral strategy for influenza virus
2011 Lee, Kelly K.; Pessi, Antonello; Gui, Long; Santoprete, Alessia; Talekar, Aparna; Moscona, Anne; Porotto, Matteo
Circulating clinical strains of human parainfluenza virus reveal viral entry requirements for in vivo infection
2014 Palmer, Samantha G.; Devito, Ilaria; Jenkins, Stephen G.; Niewiesk, Stefan; Porotto, Matteo; Moscona, Anne
Decreased differentiation of erythroid cells exacerbates ineffective erythropoiesis in β-thalassemia
2008 Libani, Ilaria V.; Guy, Ella C.; Melchiori, Luca; Schiro, Raffaella; Ramos, Pedro; Breda, Laura; Scholzen, Thomas; Chadburn, Amy; Liu, Yifang; Kernbach, Margrit; Baron-Lühr, Bettina; Porotto, Matteo; De Sousa, Maria; Rachmilewitz, Eliezer A.; Hood, John D.; Cappellini, M. Domenica; Giardina, Patricia J.; Grady, Robert W.; Gerdes, Johannes; Rivella, Stefano
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| A broad-spectrum antiviral targeting entry of enveloped viruses | 1-gen-2010 | Wolf, Mike C.; Freiberg, Alexander N.; Zhang, Tinghu; Akyol-Ataman, Zeynep; Grock, Andrew; Hong, Patrick W.; Li, Jianrong; Watson, Natalya F.; Fang, Angela Q.; Aguilar, Hector C.; Porotto, Matteo; Honko, Anna N.; Damoiseaux, Robert; Miller, John P.; Woodson, Sara E.; Chantasirivisal, Steven; Fontanes, Vanessa; Negrete, Oscar A.; Krogstad, Paul; Dasgupta, Asim; Moscona, Anne; Hensley, Lisa E.; Whelan, Sean P.; Faull, Kym F.; Holbrook, Michael R.; Jung, Michael E.; Lee, Benhur | |
| A general strategy to endow natural fusion-protein-derived peptides with potent antiviral activity | 1-gen-2012 | Pessi, Antonello; Langella, Annunziata; Capitã², Elena; Ghezzi, Silvia; Vicenzi, Elisa; Poli, Guido; Ketas, Thomas; Mathieu, Cyrille; Cortese, Riccardo; Horvat, Branka; Moscona, Anne; Porotto, Matteo | |
| A neutralizing antibody prevents postfusion transition of measles virus fusion protein | 1-gen-2024 | Zyla, Dawid S; Della Marca, Roberta; Niemeyer, Gele; Zipursky, Gillian; Stearns, Kyle; Leedale, Cameron; Sobolik, Elizabeth B; Callaway, Heather M; Hariharan, Chitra; Peng, Weiwei; Parekh, Diptiben; Marcink, Tara C; Diaz Avalos, Ruben; Horvat, Branka; Mathieu, Cyrille; Snijder, Joost; Greninger, Alexander L; Hastie, Kathryn M; Niewiesk, Stefan; Moscona, Anne; Porotto, Matteo; Ollmann Saphire, Erica | |
| A rapid high-throughput assay for the identification of neutralizing antibodies and antiviral molecules against SARS-CoV-2 virus | 1-gen-2020 | Stelitano, D; Bovier, F T; Mathieu, C; Horvat, B; Zannella, C; Folliero, V; Franci, G; Cennamo, M; Portella, G; Galdiero, M; Porotto, M | |
| A recombinant sialidase fusion protein effectively inhibits human parainfluenza viral infection in vitro and in vivo | 1-gen-2010 | Moscona, Anne; Porotto, Matteo; Palmer, Samantha; Tai, Caroline; Aschenbrenner, Lori; Triana-Baltzer, Gallen; Li, Qi-Xiang; Wurtman, David; Niewiesk, Stefan; Fang, Fang | |
| A second receptor binding site on human parainfluenza virus type 3 hemagglutinin-neuraminidase contributes to activation of the fusion mechanism | 1-gen-2007 | Porotto, Matteo; Fornabaio, Micaela; Kellogg, Glen E.; Moscona, Anne | |
| A single amino acid alteration in the human parainfluenza virus type 3 hemagglutinin-neuraminidase glycoprotein confers resistance to the inhibitory effects of zanamivir on receptor binding and neuraminidase activity | 1-gen-2001 | Murrell, M. T.; Porotto, M.; Greengard, O.; Poltoratskaia, N.; Moscona, A. | |
| A three-dimensional model of human lung development and disease from pluripotent stem cells | 1-gen-2017 | Chen, Ya-Wen; Huang, Sarah Xuelian; De Carvalho, Ana Luisa Rodrigues Toste; Ho, Siu-Hong; Islam, Mohammad Naimul; Volpi, Stefano; Notarangelo, Luigi D.; Ciancanelli, Michael; Casanova, Jean-Laurent; Bhattacharya, Jahar; Liang, Alice F.; Palermo, Laura M.; Porotto, Matteo; Moscona, Anne; Snoeck, Hans-Willem | |
| Absence of COVID-19-associated changes in plasma coagulation proteins and pulmonary thrombosis in the ferret model | 1-gen-2022 | Kreft, Iris C; Winiarczyk, Roy R A; Tanis, Fric J; van der Zwaan, Carmen; Schmitz, Katharina S; Hoogendijk, Arie J; de Swart, Rik L; Moscona, Anne; Porotto, Matteo; Salvatori, Daniela C F; de Vries, Rory D; de Maat, Moniek P M; van den Biggelaar, Maartje; van Vlijmen, Bart J M | |
| Adaptation of human parainfluenza virus to airway epithelium reveals fusion properties required for growth in host tissue | 1-gen-2012 | Palmer, Samantha G.; Porotto, Matteo; Palermo, Laura M.; Cunha, Luis F.; Greengard, Olga; Moscona, Anne | |
| Analysis of a subacute sclerosing panencephalitis (SSPE) Genotype B3 virus from the 2009/10 South African measles epidemic shows hyperfusogenic F proteins contribute to measles virus infection in the brain | 1-gen-2019 | Angius, Fabrizio; Smuts, Heidi; Rybkina, Ksenia; Stelitano, Debora; Eley, Brian; Wilmshurst, Jo; Ferren, Marion; Lalande, Alexandre; Mathieu, Cyrille; Moscona, Anne; Horvat, Branka; Hashiguchi, Takao; Porotto, Matteo; Hardie, Diana | |
| Antiviral activity of gliotoxin, gentian violet and brilliant green against Nipah and Hendra virus in vitro | 1-gen-2009 | Aljofan, Mohamad; Sganga, Michael L.; Lo, Michael K.; Rootes, Christina L.; Porotto, Matteo; Meyer, Adam G.; Saubern, Simon; Moscona, Anne; Mungall, Bruce A. | |
| Antiviral activity of nitazoxanide against Morbillivirus infections | 1-gen-2023 | Stelitano, Debora; La Frazia, Simone; Ambrosino, Annalisa; Zannella, Carla; Tay, Daniel; Iovane, Valentina; Montagnaro, Serena; De Filippis, Anna; Santoro, Maria Gabriella; Porotto, Matteo; Galdiero, Massimiliano | |
| Antiviral Lipopeptide-Cell Membrane Interaction Is Influenced by PEG Linker Length | 1-gen-2017 | Augusto, Marcelo T; Hollmann, Axel; Porotto, Matteo; Moscona, Anne; Santos, Nuno C. | |
| Authentic modeling of human respiratory virus infection in human pluripotent stem cell-derived lung organoids | 1-gen-2019 | Porotto, M.; Ferren, M.; Chen, Y. -W.; Siu, Y.; Makhsous, N.; Rima, B.; Briese, T.; Greninger, A. L.; Snoeck, H. -W.; Moscona, A. | |
| Biophysical properties and antiviral activities of measles fusion protein derived peptide conjugated with 25-hydroxycholesterol | 1-gen-2017 | Gomes, Bã¡rbara; Santos, Nuno C.; Porotto, Matteo | |
| Broad spectrum antiviral activity for paramyxoviruses is modulated by biophysical properties of fusion inhibitory peptides | 1-gen-2017 | Mathieu, Cyrille; Augusto, Marcelo T; Niewiesk, Stefan; Horvat, Branka; Palermo, Laura M; Sanna, Giuseppina; Madeddu, Silvia; Huey, Devra; Castanho, Miguel A. R. B; Porotto, Matteo; Santos, Nuno C; Moscona, Anne | |
| Capturing a fusion intermediate of influenza hemagglutinin with a cholesterol-conjugated peptide, a new antiviral strategy for influenza virus | 1-gen-2011 | Lee, Kelly K.; Pessi, Antonello; Gui, Long; Santoprete, Alessia; Talekar, Aparna; Moscona, Anne; Porotto, Matteo | |
| Circulating clinical strains of human parainfluenza virus reveal viral entry requirements for in vivo infection | 1-gen-2014 | Palmer, Samantha G.; Devito, Ilaria; Jenkins, Stephen G.; Niewiesk, Stefan; Porotto, Matteo; Moscona, Anne | |
| Decreased differentiation of erythroid cells exacerbates ineffective erythropoiesis in β-thalassemia | 1-gen-2008 | Libani, Ilaria V.; Guy, Ella C.; Melchiori, Luca; Schiro, Raffaella; Ramos, Pedro; Breda, Laura; Scholzen, Thomas; Chadburn, Amy; Liu, Yifang; Kernbach, Margrit; Baron-Lühr, Bettina; Porotto, Matteo; De Sousa, Maria; Rachmilewitz, Eliezer A.; Hood, John D.; Cappellini, M. Domenica; Giardina, Patricia J.; Grady, Robert W.; Gerdes, Johannes; Rivella, Stefano |