P1007 IMPACT OF TRAPEZIOMETACARPAL OSTEOARTHRITIS SEVERITY ON FOREARM BMD IN A COHORT OF POSTMENOPAUSALWOMEN

Objective: Osteoarthritis (OA) and osteoporosis are common diseases in older people but it is still not clear whether there is a correlation between them [1]. Trapeziometacarpal (TMC) OA is a common age-related degenerative disorder that might negatively influence the upper limb functioning. Aim of our study was to evaluate the influence of TMC OA severity on forearm BMD in a cohort postmenopausal women. Methods: We included postmenopausal women, aged ≥50 years, with a diagnosis of TMC OA (according to EULAR recommendations), with an Eaton-Glickel staging ≥2 [2]. We divided our cohort in 2 groups: mild TMC OA group (Eaton-Glickel staging 2) andmoderate-severe TMC OA group (Eaton-Glickel staging 3-4). Outcome measures were: ultradistal radius (UDR) BMD, 33% radius BMD, lumbar spine (LS) BMD, and femoral neck (FN) BMD. Results:We included 20 postmenopausal women, mean aged 68.65±6.63 years, 11 with mild TMC OA and 9 with moderate-severe TMC OA. The moderate-severe TMC OA group had a significantly lower UDR BMD (0.313±0.052 g/cm2 vs. 0.436±0.095 g/cm2; p=0.0088) and a significantly lower 33% radius BMD (0.584±0.130 g/cm2 vs. 0.778±0.166 g/cm2; p=0.0062). No statistically significant differences were found in LSBMD and FN BMD between the two groups. Conclusion: Our data reported that TMC OA might have a negative impact on forearm bone health, as showed by the significantly lower UDR and 33% radius BMD in patients affected by moderate-severe TMC OA. On the other hand, no differences were found in the other skeletal sites. References: 1. Dillon CF et al. Am J Phys Med Rehabil 2007;86:12 2. Eaton RG, Littler JW. J Bone Joint Surg Am 1973;55:1655