Two new ursolic acid triterpene derivatives, compounds 2 and 3, have been isolated from cv. Annurca apple fruit, a high-quality apple variety widely cultivated in southern Italy, together with the known 2-oxopomolic acid (1). The new compounds were identified by means of different spectroscopic techniques as 3-epi-2-oxopomolic acid (=(3α)-3,19-dihydroxy-2-oxours-12-en-28-oic acid; 2) and (1α)-1-hydroxy-3-oxours-12-en-28-oic acid (3). Compounds 1-3 were tested for their radical-scavenging activities with the aid of a 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay (Fig. 2). All three constituents showed activities similar to that of the reference antioxidant α-tocopherol (vitamin E). © 2005 Verlag Helvetica Chimica Acta AG, Zürich.

Radical-scavenging activities of new hydroxylated ursane triterpenes from cv. Annurca apples

D'ABROSCA, Brigida;FIORENTINO, Antonio;MONACO, Pietro;PACIFICO, Severina
2005

Abstract

Two new ursolic acid triterpene derivatives, compounds 2 and 3, have been isolated from cv. Annurca apple fruit, a high-quality apple variety widely cultivated in southern Italy, together with the known 2-oxopomolic acid (1). The new compounds were identified by means of different spectroscopic techniques as 3-epi-2-oxopomolic acid (=(3α)-3,19-dihydroxy-2-oxours-12-en-28-oic acid; 2) and (1α)-1-hydroxy-3-oxours-12-en-28-oic acid (3). Compounds 1-3 were tested for their radical-scavenging activities with the aid of a 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay (Fig. 2). All three constituents showed activities similar to that of the reference antioxidant α-tocopherol (vitamin E). © 2005 Verlag Helvetica Chimica Acta AG, Zürich.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11591/189437
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